Acute myeloid - AML , Blood Cancer , Coping with Cancer , General interest
Doctor and Nurse Team Up for Blood Cancers Support Group

By Ronni Gordon When my year of isolation ended after a stem cell transplant at Dana-Farber/Brigham and Women’s Cancer Center in 2003, I looked for a blood cancer support group near my home in western Massachusetts. I found support groups for just about everyone except patients like me with acute […]

April 18, 2017
0
Blood Cancer , Care for adults
What Are the Most Common Blood Cancers in Adults?

Someone in the United States is diagnosed with a blood cancer every three minutes. The most commonly diagnosed blood cancers are non-Hodgkin lymphoma, chronic lymphocytic leukemia, acute myeloid leukemia, acute lymphoblastic leukemia, and multiple myeloma.   Non-Hodgkin Lymphoma   Non-Hodgkin lymphoma (NHL) is a type of cancer that forms in […]

September 19, 2016
0
Blood Cancer , Blood disorders , Cancer research , Research
The Genomics Behind Blood Cancers and Other Blood Disorders

Many of the secrets of why precancerous conditions sometimes become cancerous are hidden in cells’ genes. At Dana-Farber, researchers are collecting tissue samples to see if they can pry open those secrets and unlock new treatment options for certain types of blood cancers and other blood disorders. They’re also exploring […]

September 13, 2016
0
Blood Cancer , Cancer research
The Latest Research in Multiple Myeloma, Leukemia and Other Blood Cancers

The last two years have been very exciting for blood cancer research; many new targeted therapies and immunotherapies are improving treatment outcomes for patients with lymphoma, leukemia and multiple myeloma. “We’re starting to see a lot of hematologic malignancies benefit from immunotherapy,” says Irene Ghobrial, MD. “The excitement is there […]

February 11, 2016
0
Blood Cancer , Care for adults , Treatments and Procedures
New, Faster Test Speeds Up Treatment for Blood Cancers

  Rapid Heme Panel, a new quick-turnaround genetic diagnostic test, at Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC), offers some patients with aggressive blood cancers faster diagnoses, and treatments. Instead of sending blood samples to different laboratories for tests that return results in two weeks or more, Rapid Heme Panel puts […]

December 29, 2014
0
Blood Cancer , Cancer research , Research , Treatments and Procedures
The Latest Research and Treatment for Blood Cancers and Disorders

In the treatment of blood cancers and disorders, doctors and researchers are focusing their sights on the immune system and how to bolster its ability to fight off diseases like leukemia, lymphoma and multiple myeloma. “Understanding how you control the immune system is a big theme in treatment for these […]

December 26, 2014
0
Blood Cancer
What Are the Symptoms of The Rare Blood Cancer BPDCN?

Blastic plasmacytoid dendritic cell neoplasm, or BPDCN, is a rare, aggressive blood cancer, with features of both lymphoma and leukemia. While it is somewhat similar to acute myeloid leukemia (AML), its unique characteristics include abnormal tumor cells that can be found in the blood, bone marrow, lymph nodes, or skin. […]

August 31, 2017
0
Blood Cancer , Cancer research , Leukemias , Lymphomas , Multiple Myeloma , Research , Stem cell/Bone marrow transplant
The Latest Advances Against Hematologic Cancers

Treatment of blood-related, or hematologic, cancers is seizing on insights into the basic genetic wiring of cancer cells and the body’s system for finding and attacking those cells. Research presentations at the annual American Society of Hematology (ASH) meeting in December gave evidence of how broad, and rapid, the progress […]

April 21, 2017
2
Cancer research , Risk and Prevention , Treatments and Procedures
How Does Radiation Raise the Risk of Other Cancers?

Along with chemotherapy, radiation therapy is a common method for treating cancer; about half of patients receive the therapy, which uses high-energy radiation to shrink tumors and kill cancer cells, during the course of their treatment. While radiation therapy is effective against cancer cells, it also leaves its mark on […]

April 14, 2017
0
Cervical Cancer , General interest , Risk and Prevention
What Are AIDS-Related Cancers?

People infected with human immunodeficiency virus (HIV) or AIDS are more susceptible to certain types of cancer than people who are not infected. In fact, some types of cancers are so common in people with HIV that they are referred to as AIDS-related or AIDS-defining cancers – including Kaposi’s sarcoma, […]

December 1, 2016
0
Cancer research , Care for adults , Patient Stories, Adult , Research
Precursor Blood Condition Patient Pays it Forward

When Lori Kauzlarich discovered that she had a precursor blood condition in August 2013, she sprang into action. “I was stunned,” she says. “But I decided to advocate for myself.” Precursor conditions are blood disorders that may evolve into cancers such as leukemia, Waldenström’s macroglobulinemia, and multiple myeloma. They are […]

September 2, 2016
0
Blood Cancer , Blood disorders , Care for adults
What is a Benign Blood Disorder?

It might sound counterintuitive, but not every patient comes to Dana-Farber for cancer treatment. For example, the Institute’s experts regularly see patients seeking help with benign (non-cancerous) blood disorders. Benign blood disorders such as anemia and sickle cell disease are often treated at cancer centers because such institutions are home […]

August 4, 2016
0
Blood Cancer , Cancer research , Treatments and Procedures
What Are Precursor Blood Conditions and How Are They Treated?

Precursor conditions are early phases of blood diseases that may develop into cancers such as lymphoma, leukemia, Waldenström’s macroglobulinemia, and multiple myeloma. Most people do not experience symptoms, and since doctors rarely screen for precursor conditions, they are often diagnosed after routine blood tests. “Many diagnoses are purely incidental,” says […]

July 15, 2016
0
Cancer research , Immunotherapy , Susan F. Smith Center , Treatments and Procedures
Fighting Women’s Cancers from Within

Traditionally, the war on cancer has been waged from the outside in, with therapies such as surgery, radiation, and drugs entering the body from external sources. For more than 100 years, however, a notion has persisted that the most formidable tool against cancer may come from within: the immune system. […]

June 27, 2016
0
Care for adults , Research , Risk and Prevention
What Are the Most Common Cancers in Men?

Information about cancer risk can help you make informed decisions about screening and prevention strategies. As we recognize National Men’s Health Week, learn about the most common cancers in men in the United States and the options for prevention and treatment. 1. Prostate cancer There will be an estimated 180,890 new […]

June 13, 2016
0
General interest , Health Topics , Research
What Are the Most Common Cancers in Women?

While there is no sure method for avoiding cancer, understanding risk factors can help you make decisions about prevention and screening for early signs of disease. As we recognize National Women’s Health Week, here’s a look at the five most common cancers in women* and steps you can take to […]

May 9, 2016
0
Cancer Genetics , Care for children , Patient Stories, Pediatric
How Genetics Can Help Predict — and Sometimes Stop — Childhood Cancers

Amy Kindstedt hates cancer, but the 9-year-old is very thankful for one thing: Because genetic testing on her baby brother Hunter revealed he had the same genetic mutation she did, his cancer was caught much earlier –  possibly sparing him the same level of intense treatment she endured. The mapping […]

February 26, 2016
0
Blood Cancer , Care for adults , Research , Treatments and Procedures
What’s New in Research for Blood Cancer Treatments?

The past two years have seen a surge of new treatments for blood cancers, such as lymphoma, leukemia and multiple myeloma. Research on the genetic flaws underlying specific cancer types has led to new precision drugs such as ibrutinib and idelalisib and new immunotherapy agents that are improving outcomes in […]

September 30, 2015
2
General interest , Risk and Prevention
What Are the Most Common Cancers in Each Age Group? [Infographic]

As we age, the overall risk of cancer increases. However, the type of cancer for which we are at risk varies. For example, the likelihood of someone younger than 20 years old developing cancer is quite low; only 0.19 cases will be diagnosed per 1,000 children annually. If they do develop […]

August 7, 2015
1
Treatments and Procedures , Uncategorized , Waldenstrom’s macroglobulinemia
New Treatment Option for Patients with Rare Blood Cancer

It’s commonly thought that targeted therapy for cancer requires the development of separate drugs for each type and subtype of cancer. The recent approval of the drug ibrutinib (Imbruvica®), however, for Waldenström’s macroglobulinemia (a rare form of lymphoma) shows the opposite to be true: a single agent can be effective against […]

February 18, 2015
1
General interest , Survivorship
Can Cancer Survivors Donate Blood or Platelets?

Blood products like whole blood and platelets are lifesaving for cancer patients at Dana-Farber and elsewhere. It comes as no surprise, then, that many cancer survivors want to return the favor by donating at the Kraft Family Blood Donor Center, which collects blood products to benefit patients at both Dana-Farber […]

January 16, 2015
4
Care for adults , Gynecologic Cancer
What are the Main Types of Gynecologic Cancers?

Close to 100,000 women are diagnosed with a gynecologic cancer in the United States each year. In recognition of Gynecologic Cancer Awareness Month, we’re taking a look at the main types of gynecologic cancers and their symptoms. Cervical cancer In cervical cancer, cancer cells form in the tissues of the […]

September 15, 2014
2
Care for adults , General interest
How Donated Blood and Platelets Help Cancer Patients [Infographic]

If you’ve ever donated blood or platelets, there’s a reasonable chance that your donation went to help a cancer patient. That’s because cancer and certain treatments can damage blood cells, which means some patients may need transfusions of one or more types of blood components:

January 24, 2014
1
Cancer research , Diet and Nutrition , General interest , Health Topics
New Study: Nuts Linked to Reduced Risk of Pancreatic and Other Cancers

An analysis of data from the decades-long Nurses’ Health Study revealed that women who ate a one-ounce serving of nuts – any kind of nuts – two or more times a week had a 35 percent lower risk of pancreatic cancer than women who abstained from them. That’s a significant […]

December 18, 2013
1
Blood Cancer , Cancer research
Blood cancer research may lead to new treatments

At this year’s American Society of Hematology Annual Meeting, Dana-Farber scientists presented major findings that could one day improve diagnosis and treatment of blood cancers, extend life, or even cure some diseases. Among the highlights: Steven Treon, MD, PhD, and his colleagues identified a gene mutation that underlies the vast […]

December 13, 2011
0
Blood Cancer
What is a Bone Marrow Biopsy and How Does it Work?

In a bone marrow biopsy, a doctor uses a needle to remove and examine a small amount of bone marrow, the spongy tissue inside some of the body’s larger bones. Bone marrow, which generates all the different kinds of cells within the blood, has the consistency of a gel in […]

December 4, 2017
0
Research
What is CRISPR and How Can It Help Cancer Research?

CRISPR, a powerful new tool for editing the DNA instruction manual in animals and humans, is proving a boon to cancer research. Scientists say CRISPR has dramatically accelerated the process of making animal models of cancer and is speeding the search for new molecular targets for cancer drugs. The technique […]

November 17, 2017
0
Stem cell/Bone marrow transplant
What’s the Process Involved in a Stem Cell Transplant?

A stem cell transplant is an infusion of healthy stem cells. Stem cells are located within the bone marrow and are the cells from which all other blood cells and the immune system are created. Introducing healthy stem cells into the blood enables the production of all of the different […]

November 2, 2017
2
CAR T-cell therapy , Non-Hodgkin lymphoma
FDA Approves CAR T-Cell Therapy for Non-Hodgkin Lymphoma

A drug called Axicabtagene ciloleucel (KTE-C19) has become the first chimeric antigen receptor (CAR) T-cell therapy approved to treat a form of cancer in adults, the Food and Drug Administration (FDA) announced today. The decision means the drug, known as Yescarta, can now be used for some adults with refractory aggressive non-Hodgkin lymphoma […]

October 18, 2017
0
CAR T-cell therapy , Patient Stories, Adult , Research
CAR T-Cell Therapy Gives Cancer Patients New Hope

Judy Wilkins tried four different chemotherapy regiments over 18 grueling months to try to put her lymphoma into remission. Her team never could. But thanks to CAR T-cell therapy, an emerging immunotherapy treatment that is showing great promise in clinical trials nationwide, Wilkins is cancer-free. CAR (Chimeric Antigen Receptor) T-cell therapy […]

September 19, 2017
1
CAR T-cell therapy , Stem cell/Bone marrow transplant
Stem Cell Transplants and Cellular Therapies: What’s the Difference?

Donor stem cell transplants and other cellular therapies are treatment approaches that harness the immune system to fight cancer using cells from the patient or from healthy donors. Stem cell transplants are used to treat blood-related cancers such as leukemia, lymphoma, and multiple myeloma, as well as certain non-cancerous blood […]

September 7, 2017
0
Cancer research , Immunotherapy
What’s New in Treatment of Adult Histiocytic Disorders?

While blood cancers known as adult histiocytic disorders are very rare and many patients do well with today’s treatments, researchers are working to improve outcomes with therapies targeted to newly discovered mutations – and they are about to begin testing immunotherapies, too. Histiocytic disorders involved overproduction of immune white cells, […]

June 29, 2017
0
Cancer research , CAR T-cell therapy , General interest
CAR T-Cell Therapy: How Does It Work?

CAR T-cell therapy is a kind of cellular therapy, which uses a patient’s own immune system cells to rally an attack on cancer. They’re made by removing a specific set of cells from the blood, modifying them in a lab to intensify the immune system’s natural response to cancer, and […]

June 2, 2017
2
Lymphomas , Non-Hodgkin lymphoma , Patient Stories, Adult
Pregnant with Non-Hodgkin Lymphoma, This Mom Found Care and Comfort at Dana-Farber

Elizabeth Larcom has six children, but it’s the youngest that she calls her “miracle baby” – and with good reason. In August 1997, the Army moved the Larcom family to Alaska with five kids under 12 and mom Elizabeth pregnant with the sixth. Soon after, husband and dad, Chuck, left […]

May 11, 2017
0
Cancer research , General interest , Immunotherapy
The Progress of Cancer Immunotherapy: The Tip of the Iceberg

If the human immune system was a powerful racing car, you could say that scientists in the past few years have gained unprecedented control over how to make it accelerate, and what causes it to slow or stop. This knowledge has spawned new immunotherapy drugs that are delivering dramatic benefits […]

May 9, 2017
2
General interest , Multiple Myeloma
Signs and Symptoms of Multiple Myeloma

Multiple myeloma, also called Kahler’s disease, is a type of cancer that begins in plasma cells – white blood cells that produce antibodies. Plasma cells usually work in the body’s immune defense system and help produce antibodies. In cases of multiple myeloma, however, too many plasma cells build up in the […]

March 21, 2017
0
Care for adults , Stem cell/Bone marrow transplant
Tips for Celebrating the Holidays after a Stem Cell Transplant

The holidays can be a happy time of family gatherings and traditions, but the combination of extended family and friends and cold and flu season can be dangerous for patients who are immunocomprised following recent stem cell transplants to treat blood cancers including multiple myeloma, leukemia, lymphoma, and related disorders. […]

December 21, 2016
0
Cancer research , Immunotherapy , Research
What’s New in Cancer Immunotherapy?

Keeping up with progress in the field of cancer immunotherapy requires paying close attention. The number of approved drugs that help the body’s immune system fight cancer continues to grow, as does the list of different cancers in which immunotherapy is proving effective – in some cases yielding dramatically longer-lasting […]

September 27, 2016
1
Care for adults , Histiocytosis
What Are Adult Histiocyte Disorders?

Adult histiocyte disorders are a group of rare diseases that involve an over-production of white blood cells known as histiocytes, which destroy foreign substances and protect the body from infection. In adults, Langerhans cell histiocytosis (LCH) is the most common of these diseases. LCH arises when specialized histiocytes called dendritic […]

September 26, 2016
0
General interest , Health and Wellness , Risk and Prevention
Is Itching a Sign of Cancer?

Itchy skin has many causes, including dryness and allergies, but only rarely does it signal that a person has cancer. This symptom may occur as a result of complications of the disease, and itchy, flaky skin and rashes are common side effects of some cancer drugs. Most skin cancers, such as […]

August 25, 2016
6
Care for adults , Research , Treatments and Procedures
What is an Angiogenesis Inhibitor and How Can It Be Used to Treat Cancer?

Tumors can’t grow any larger than the size of a pinhead unless the body generates a network of new blood vessels to nourish them – a process known as angiogenesis. So using drugs called angiogenesis inhibitors to block this process is an ingenious strategy with many potential advantages over standard […]

July 25, 2016
0
Care for adults , Chronic lymphocytic - CLL , Chronic myelogenous - CML , Leukemias
What Are the Differences Between Lymphocytic and Myelogenous Leukemia?

Leukemia arises from malfunctions in stem cells within the bone marrow that cause abnormal white blood cells to flood into the bloodstream. Leukemias are classified as either myelogenous (also called myeloid) or lymphocytic depending on which types of white blood cells are affected. If the abnormal cells are primarily granulocytes […]

July 19, 2016
0
Leukemias , Multiple Myeloma , Podcasts
Cancer Conversations Podcast – Episode #4: The Latest Research in Multiple Myeloma and Leukemia

With new research in immunotherapy and targeted therapy, treatment options for blood cancer patients are rapidly expanding. Combination therapies have also caused much excitement among researchers and physicians, and ongoing clinical trials are continuing to look at new strategies that use multiple drugs for fighting these diseases. In this Cancer […]

February 26, 2016
0
Cancer research , Treatments and Procedures
Know Your Surroundings: How Cancer Treatments Can Keep Cells From Supporting Tumors

By Eric Bender Multiple myeloma is a poster child for recent advances in treatment: In the past decade, the U.S. Food and Drug Administration (FDA) approved no fewer than nine treatments for the blood cancer, and several more drug approvals appear to be near. Not coincidentally, multiple myeloma is also […]

June 19, 2015
2
Cancer research , Immunotherapy , Treatments and Procedures
Immunotherapy, Targeted Drugs, Brain Cancer Research Among Highlights at Cancer Meeting

Eagerly awaited new data from trials of immunotherapy drugs, vaccines to treat brain tumors, and improved treatments for blood cancers sparked waves of optimism at the year’s biggest cancer meeting. The 2015 annual meeting of the American Society of Clinical Oncology (ASCO) drew about 30,000 cancer specialists to Chicago May […]

June 5, 2015
0
General interest
Doctor’s Journey Out of Saigon Inspires Clinical Career

For some patients with blood cancers and related disorders, a stem cell transplant offers the possibility of a new beginning. Vincent Ho, MD, clinical director of the Stem Cell Transplantation Program at Dana-Farber/Brigham and Women’s Cancer Center, is no stranger to this feeling of starting fresh. He had his own […]

May 29, 2015
2
Cancer research , Immunotherapy
What is the Science of PD-1 and Immunotherapy?

This is a story about the velocity of an idea – a discovery whose potential to improve cancer treatment practically leapt from the test tube. The groundwork was laid in the 1990s, when scientists learned that human cells carry certain proteins on their surface that enable them to escape attack […]

May 13, 2015
1
Care for adults , Care for children , Stem cell/Bone marrow transplant
Answers to Common Questions About Stem Cell Transplants

Stem cell transplantation can be a life-saving treatment option for patients with blood cancers or disorders. The procedure, sometimes called bone marrow transplantation, replaces bone marrow that doesn’t work correctly or has been damaged by disease. We spoke with Joseph Antin, MD, chief of the Stem Cell Transplantation Program at […]

March 27, 2015
6
Brain tumors , Cancer research , Care for adults , Treatments and Procedures
Collaborative Effort Helps Develop More Effective Treatment for Brain Tumors

The information used in diagnosing a brain tumor takes many forms. At Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC), patients’ brain tumor tissue undergoes a broad range of diagnostic tests: not only standard pathology exams in which tumor cells are viewed under a microscope, but also next-generation scans for mutated genes […]

February 4, 2015
0
Chemotherapy , General interest , Immunotherapy
How Does Chemotherapy Work? Including Oral Chemotherapy and Immunotherapy

More than half of all people with cancer will get chemotherapy – powerful drugs that kill cancer cells to cure the disease, slow its growth, or reduce its symptoms. There are more than 100 different drugs used in chemotherapy, sometimes alone, but more often in combinations that have proven effective […]

November 10, 2014
5
Care for adults , Care for children , Patient Stories, Adult
Mother and Son, Both Cancer Survivors, Share Their Story on Radio-Telethon

When Lisa Robert is interviewed at Fenway Park  for the WEEI/NESN Jimmy Fund Radio-Telethon presented by Arbella Insurance Foundation (Aug 19-20), her mind will no doubt drift back to 1976, when she was a 7-year-old leukemia patient at Dana-Farber and had the thrill of her life. She threw out the […]

August 20, 2014
0
General interest , Health Topics
Can Coloring Our Hair Cause Cancer?

The use of hair dyes is widespread. It’s estimated that more than a third of women over age 18 and 10 percent of men over age 40 – a group that numbers in the millions in the U.S. alone – color their hair. Even if exposure to hair dye increases […]

August 14, 2013
1
Cancer research , Treatments and Procedures
Clinical Trials for Cancer Patients

By Ian Krop, MD, PhD Clinical trials are scientific studies in which new treatments – drugs, diagnostic procedures, and other therapies – are tested in people to find out if they are safe and effective. Nearly all cancer drugs in use today were tested in clinical trials.

June 10, 2013
4
Care for children , Treatments and Procedures
Treating childhood cancer worldwide

On International Childhood Cancer Day, it’s important to remember that global support, research, and treatment are vital to ensuring that children in developing countries have the same chance at survival as their peers in the U.S. Physicians such as Dr. Leslie Lehmann from Dana-Farber/Boston Children’s Cancer and Blood Disorders Center travel […]

February 14, 2012
0
Hodgkin lymphoma , Lymphomas , Non-Hodgkin lymphoma
What Are the Different Stages of Lymphoma?

After a patient is diagnosed with lymphoma, doctors determine the stage of the disease – or how widespread the cancer is – and then come up with a treatment plan. As with most cancers, there are generally four different stages of lymphoma: I, II, III, and IV. In stage I […]

December 14, 2017
0
Pancreatic cancer
Why is Pancreatic Cancer So Difficult to Treat?

Pancreatic cancer is seldom detected early enough for curative treatment to be performed – and even if it were, it would still be very difficult to vanquish. The pancreas, a narrow, six-inch-long gland that makes digestive juices and hormones such as insulin, is tucked away deep inside the body behind […]

December 13, 2017
0
Blood Cancer , Immunotherapy
What Does It Mean to Have Inoperable Cancer?

A cancer can be inoperable for a variety of reasons. “Liquid cancers,” such as leukemia, lymphoma, and multiple myeloma, are considered inoperable by nature, because they involve cells or tissues that are dispersed throughout the body. Leukemia and multiple myeloma, for example, originate in abnormal cells of the bone marrow, […]

December 1, 2017
0
Blood disorders, childhood , Immunotherapy , Uncategorized
CRISPR Enables Cancer Immunotherapy Drug Discovery

This originally appeared on Vector, Boston Children’s Hospital’s blog. A novel screening method using CRISPR-Cas9 genome editing technology has revealed new drug targets that could potentially enhance the effectiveness of PD-1 checkpoint inhibitors, a promising new class of cancer immunotherapy. The method, developed by a team at Dana-Farber/Boston Children’s Cancer and […]

November 30, 2017
0
Childhood , Patient Stories, Pediatric , Precision Cancer Medicine
How Precision Medicine Turned Jesus’ Unique Tumor into an Operable One

This post originally appeared on Thriving, Boston Children’s Hospital’s pediatric health blog. On a hot, August day in a Boston park, Jesus Apolinaris Cruz cooled off with a water squirt gun fight with his mother and sister. As he nimbly ran and dodged their aim, he twisted around to sneak shots […]

November 29, 2017
0
Pancreatic cancer
Pancreatic Cancer: What are the Signs and Symptoms?

Pancreatic tumors are sometimes discovered during imaging studies — such as an MRI or CT scan — performed to investigate the onset of new symptoms or during evaluation for another condition. They may also be identified during screening for families with a known history of pancreatic cancer. The pancreas produces […]

November 28, 2017
0
Research
When Research Into One Cancer Sheds Light on Another: A Scientist’s Story

Whenever an advance against cancer is reported, it’s easy to imagine that it came about in an orderly and straightforward manner.

November 27, 2017
0
Prostate cancer
Benign Prostatic Hyperplasia (BPH) and Prostate Cancer: What’s the Difference?

Benign prostatic hyperplasia (BPH) and prostate cancer both involve enlargement of the prostate, the walnut-sized gland that produces fluid that makes up a portion of semen. The prostate sits below the bladder and surrounds the urethra, the tube that carries urine out of the body. When the prostate increases in […]

November 9, 2017
0
Bladder cancer , Breast cancer , CAR T-cell therapy , Childhood , Colon Cancer , Hodgkin lymphoma , Immunotherapy , Kidney cancer , Liver cancer , Melanoma , Prostate cancer
Cancer Treatment: A Look at How It Has Evolved in 70 Years

In 1947, when Dana-Farber Cancer Institute founder Sidney Farber, MD, set out to find a drug treatment for childhood leukemia, cancer treatment took two forms – surgery to cut out cancerous masses, and radiation therapy to burn them out. Cancers that couldn’t be removed or irradiated – either because of their […]

November 3, 2017
0
Childhood , Precision Cancer Medicine
MATCHing Precision Medicine to All Kids With Cancer

This originally appeared on Vector, Boston Children’s Hospital’s blog. A multi-center clinical trial is now offering nationwide genetic profiling services to pediatric and young adult cancer patients across the U.S. The goal is to identify gene mutations that can be individually matched with targeted drugs. “This is the first-ever nationwide […]

November 1, 2017
0
Liver cancer
Signs and Symptoms of Liver Cancer [Infographic]

Primary liver cancer is cancer that forms in the tissues of the liver. Secondary liver cancer is cancer that spreads to the liver from another part of the body. Most liver cancer is secondary or metastatic. Primary liver cancer, which starts in the liver, accounts for about 2 percent of […]

October 31, 2017
0
Exercise , Health Topics
Diabetes and Cancer: What’s the Link?

People with diabetes are at higher risk for some, but not all, forms of cancer. The relationship between the two diseases is complex and surrounded with unanswered questions. The strongest links are for cancers of the liver, pancreas, and endometrium, which are twice as likely to occur in people with […]

October 24, 2017
0
Brain tumors, childhood , Patient Stories, Pediatric
Pediatric Survivors and Parents Find School Liaison Program is a Lifeline

Harry Clark has faced many academic challenges in his dozen years of brain cancer treatment, but through surgeries, radiation, and chemotherapy, one person has always been there to guide and reassure the high school junior and his family on scholastic matters. School psychologist Marybeth Morris, EdM, is one half of […]

October 23, 2017
0
Leukemias, childhood , Patient Stories, Pediatric
Pediatric Patient and Social Worker Forge Bond From Clinic to College

Like many of Dana-Farber’s youngest patients, 3-year-old Hannah Packman brought a favorite plaything to each of her Jimmy Fund Clinic visits. Lulu the doll, however, was unique because of the extra attention she received from pediatric social worker Deborah Berk, LICSW. When Hannah had a blood draw, Berk arranged for […]

October 16, 2017
0
Immunotherapy , Lymphomas
How is Immunotherapy Used to Treat Lymphoma?

While new types of immunotherapy are being used to treat a wide variety of cancers, immunotherapy has been a front-line treatment for lymphoma for decades. Lymphoma occurs when white blood cells known as lymphocytes grow abnormally. There are nearly 70 subtypes of Hodgkin lymphoma and non-Hodgkin lymphoma that have been […]

September 14, 2017
0
Immunotherapy , Ovarian cancer , Uncategorized
Ovarian Cancer and Immunotherapy: An Update

Immunotherapy has revolutionized the treatment of many types of cancer and is now undergoing testing in ovarian cancer. Clinical trials of drugs known as immune checkpoint inhibitors, which can unleash a potent immune system attack on cancer cells, have produced remissions in about 10-15 percent of patients with advanced and […]

September 8, 2017
0
Hodgkin lymphoma , Lymphomas
Hodgkin Lymphoma Survivorship and Follow-Up Care

Adult Hodgkin lymphoma has one of the highest cure rates among all cancers. Still, the standard lymphoma therapies – including chemotherapy, radiation, surgery, and steroid therapy – may result in long-term side-effects beginning during treatment, and/or late-term effects arising years or decades after treatment. This is why check-ups and screenings […]

September 1, 2017
0
CAR T-cell therapy , Leukemias, childhood
FDA Gives First-Ever Approval to CAR T-Cell Therapy

The Food and Drug Administration (FDA) announced today that a drug called CTL019 has become the first chimeric antigen receptor (CAR) T-cell therapy approved to treat a form of cancer. The decision means the drug can be used as standard therapy for the treatment of pediatric and young adult patients with […]

August 30, 2017
0
Colon Cancer , Diet and Nutrition
Vitamin D: Can It Prevent or Slow Cancer?

Vitamin D may prevent or slow some types of cancer, according to some intriguing studies. However, the evidence is not yet definitive, and no recommendations currently exist on taking extra vitamin D to prevent cancer. Vitamin D is a nutrient that helps the body use calcium and phosphorus to build […]

August 29, 2017
0
Acute lymphoblastic - ALL , CAR T-cell therapy , Non-Hodgkin lymphoma , Research
What Are The Side Effects of CAR T-Cell Therapy?

CAR T-cell therapy is a form of immunotherapy in which patients’ T cells are modified to become better at tracking down and destroying tumor cells. CAR T cells are made by extracting thousands of a patient’s T cells, sending them to a lab where they’re outfitted with genes and proteins […]

August 17, 2017
0
General interest
Patrice Kelly’s Journey from Jimmy Fund Clinic Mom to Breast Cancer Patient

Charlotte Kelly hated having her chemotherapy port accessed, but her mother, Patrice, found a way to calm the toddler. Each time tears came, Patrice would rub her nose against Charlotte’s – and the pair would get past their fears together. Today the ritual continues, even though Charlotte’s last neuroblastoma checkup […]

June 28, 2017
0
General interest , Health Topics
How to Minimize Heart Problems Following Cancer Treatment

As more people are surviving cancer than ever before, greater attention is being focused on the cardiotoxicity of therapies and their long-term effects on the heart. Radiation therapy and a number of commonly used chemotherapy drugs can impair heart function, says Anju Nohria, MD, a cardiologist who leads the cardio-oncology […]

June 26, 2017
1
Cancer research , CAR T-cell therapy , Immunotherapy , Research
Catch Me if You Can: Finding Cancer Cells that Hide in Plain Sight

In the high-stakes contest of hide-and-seek between cancer cells and the human immune system, the advantage doesn’t always lie with the body’s defenders. A new approach to treatment, known as CAR T-cell therapy, may shift that balance of power. Cancer cells conceal themselves from the immune system not by barricading […]

June 21, 2017
0
Care for children
College Student Reconnects with the Oncologist Who Saved Her Life

This post originally appeared on Thriving, the Boston Children’s Hospital blog. Anna Protsiou was 5 when she was diagnosed with neuroblastoma in 2002. She remembers pain, and fruit-scented anesthesia masks that led her to stop eating cherries. She also remembers hospital arts and crafts projects. What she barely remembers is […]

June 20, 2017
0
General interest
What’s the Difference between Chemotherapy Drugs and Antibody Drugs?

Both chemotherapy and antibody agents are used in the treatment of cancer. In its broadest definition, cancer chemotherapy refers to any drug that destroys cancer cells or slows their growth and reproduction. As the “chemo” in their name suggests, however, true chemotherapy agents consist of chemicals that kill fast-growing cancer […]

June 9, 2017
0
Brain tumors , Care for adults , Glioblastoma , Immunotherapy , Patient Stories, Adult
A Brain Tumor Kept at Bay by Immunotherapy

It’s 19 months after being diagnosed with the aggressive brain tumor, glioblastoma, and Andrew Wall is itching to go back to work as a police officer. “Sitting around is not my thing,” says Wall, 53, who hasn’t yet been cleared to return to work as a police officer in Monroe, […]

May 29, 2017
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