Research
How Clinical Trials Move Cancer Treatment Forward

Dana-Farber's Geoffrey Shapiro, MD, PhD, answers common questions about clinical trials and how they help improve cancer treatment.

May 21, 2018
2
Cervical Cancer , Immunotherapy
New Clinical Trials Test Immunotherapy for Cervical Cancer

Researchers are applying the knowledge they’ve gained in previous clinical trials as they look into how immunotherapy might provide additional treatment options for patients with recurrent cervical cancer.

March 8, 2018
0
Metastatic breast cancer , Patient Stories, Adult
Clinical Trials and Canine Companion Help Metastatic Breast Cancer Patient

Each time the metastatic breast cancer spreads too deeply into Sayde Patel’s lungs, she changes clinical trials. And after six switches in 10 years, she maintains a glass-half-full attitude about the process.

February 23, 2018
0
Cancer research , Podcasts
Cancer Mythbusters Episode #5: Cancer Clinical Trials

Clinical trials are scientific studies in which new treatments – drugs, diagnostic procedures, and other therapies – are tested to determine if they are safe and effective for patients. Nearly all cancer drugs in use today were tested and made available to patients through clinical trials, making them a crucial component of […]

June 1, 2017
0
Cancer research , General interest , Research
What Can Be Learned from Clinical Trials that Fail?

When a clinical trial shows that a new treatment is no better than the standard, it can be disappointing. But such outcomes yield valuable, potentially lifesaving information. Trials can “fail” if the experimental therapy doesn’t work better than current treatments. These “negative” outcomes are important for several reasons. They can […]

October 14, 2016
0
Cancer research , Care for adults
Five Common Myths About Clinical Trials

Better cancer treatments depend on clinical trials of new drugs and other therapies, but in the United States, only 3 percent of cancer patients participate in these investigations of new therapies. Patients often hesitate to participate because they don’t understand the process or have misconceptions about what it means for […]

March 9, 2015
2
Cancer research , Treatments and Procedures , Vulvar cancer
Clinical Trials Paving the Way for Improved Vulvar Cancer Treatment

Cancers of the vulva – the external portion of the female genitals – are diagnosed in approximately 4,700 women in the United States each year. While many patients can be cured by a combination of surgery, chemotherapy, and radiation therapy, others – particularly those whose cancer has metastasized to other […]

March 18, 2014
3
Cancer research , Care for adults , Lymphomas , Treatments and Procedures
Clinical Trials and the Future of Lymphoma Treatment

Current lymphoma therapies are a far cry from the mustard gas used more than 50 years ago. More treatment options, including ones that may be more effective and less toxic, are being studied in ongoing clinical trials. “Clinical trials really are the future of lymphoma treatment,” says Ann LaCasce, MD, […]

November 14, 2013
1
Cancer research , Treatments and Procedures
Clinical Trials for Cancer Patients

By Ian Krop, MD, PhD Clinical trials are scientific studies in which new treatments – drugs, diagnostic procedures, and other therapies – are tested in people to find out if they are safe and effective. Nearly all cancer drugs in use today were tested in clinical trials.

June 10, 2013
4
Patient Stories, Adult
Rare Blood Cancer Patient is Cancer-Free After Clinical Trial

Keith Rohleder was diagnosed with a rare, aggressive blood cancer that most people have never heard of. But a new clinical trial put him into remission.

June 15, 2018
0
Research
Basic, Clinical and Translational Research: What’s the Difference?

“Research” is a broad stroke of a word, the verbal equivalent of painting a wall instead of a masterpiece. There are important distinctions among the three principal types of medical research — basic, clinical and translational. Whereas basic research is looking at questions related to how nature works, translational research […]

December 12, 2017
0
Cancer genetics, childhood , Care for children , Research
Gene Therapy Halts Progression of Cerebral Adrenoleukodystrophy in Clinical Trial

This originally appeared on Vector, Boston Children’s Hospital’s blog. Adrenoleukodystrophy — depicted in the 1992 movie “Lorenzo’s Oil” — is a genetic disease that most severely affects boys. Caused by a defective gene on the X chromosome, it triggers a build-up of fatty acids that damage the protective myelin sheaths of the […]

December 7, 2017
0
Cancer research
How Do I Find The Right Clinical Trial For Me?

Clinical trials are research studies that explore whether new treatments, diagnostic techniques, or disease-prevention strategies are safe and effective in patients. They may be an option when patients no longer benefit from standard therapies. They may also offer an alternative to standard therapies, particularly if the agent being tested is […]

January 17, 2017
0
Care for adults , Ovarian cancer , Patient Stories, Adult , Treatments and Procedures
Clinical Trial Helps Betsy Brauser Live with Ovarian Cancer

As researchers and clinicians in the Susan F. Smith Center for Women’s Cancers at Dana-Farber continue studying the benefits of a two-drug combination in slowing progression of recurrent ovarian cancer, one patient is as a beacon of hope for her caregivers – and for others facing the disease. Betsy Brauser, […]

July 7, 2016
0
Cancer research , Care for adults , Patient Stories, Adult
Individualized Clinical Trial Gives Patient with Rare Cancer Time to Celebrate

Kerri Antonuccio marked her 40th birthday this spring with a fresh lease on life. For the first time since 2012, she didn’t feel too sick from cancer treatment to enjoy her big day. She was also able to travel to Mexico and serve as matron of honor at her sister’s […]

June 20, 2016
2
Care for adults , Metastatic breast cancer , Treatments and Procedures
Choosing a Clinical Trial for Metastatic Breast Cancer

When facing a diagnosis of metastatic breast cancer, patients often have many questions about clinical trials: Is a clinical trial right for me? When is a good time to consider a clinical trial? What types of treatments might be available? While there may be many questions about the process, the […]

June 9, 2016
0
Care for adults , Treatments and Procedures
Can Cancer Patients Participate in More Than One Clinical Trial at a Time?

Clinical trials are a key part of medical science’s effort to improve treatments for cancer patients. There are a variety of different types of trials, including therapeutic clinical trials, which test the safety and effectiveness of potential new agents in patients. Some patients participate in several therapeutic clinical trials, in […]

December 22, 2015
0
Cancer research , Care for adults , Patient Stories, Adult
What Is It Like to Enroll in a Clinical Trial?

When Elizabeth Cahn was presented with her treatment options for triple-negative breast cancer, the decision was about more than just getting healthy; it was about “paying it forward.” “I know there are many people who participated in clinical trials before I came along and it was because of their participation […]

March 31, 2015
1
Cancer research , Treatments and Procedures
What is a Phase I Clinical Trial?

Nearly all cancer drugs in use today were developed through clinical trials. But before they are approved for use, they must go through multiple phases designed to test the drug’s safety and efficacy. These phases include preclinical, phase I, II, and III. In phase I clinical trials, investigators evaluate how […]

June 6, 2014
2
Childhood , Germ cell tumors, childhood
What to Know About Pediatric Germ Cell Tumors

Findings from clinical trials have increased survival rates significantly in the last several decades for children with germ cell tumors.

May 29, 2018
0

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