Cancer research , Podcasts
Cancer Mythbusters Episode #5: Cancer Clinical Trials

Clinical trials are scientific studies in which new treatments – drugs, diagnostic procedures, and other therapies – are tested to determine if they are safe and effective for patients. Nearly all cancer drugs in use today were tested and made available to patients through clinical trials, making them a crucial component of […]

June 1, 2017
0
Cancer research , General interest , Research
What Can Be Learned from Clinical Trials that Fail?

When a clinical trial shows that a new treatment is no better than the standard, it can be disappointing. But such outcomes yield valuable, potentially lifesaving information. Trials can “fail” if the experimental therapy doesn’t work better than current treatments. These “negative” outcomes are important for several reasons. They can […]

October 14, 2016
0
Cancer research , Care for adults
Five Common Myths About Clinical Trials

Better cancer treatments depend on clinical trials of new drugs and other therapies, but in the United States, only 3 percent of cancer patients participate in these investigations of new therapies. Patients often hesitate to participate because they don’t understand the process or have misconceptions about what it means for […]

March 9, 2015
2
Cancer research , Treatments and Procedures , Vulvar cancer
Clinical Trials Paving the Way for Improved Vulvar Cancer Treatment

Cancers of the vulva – the external portion of the female genitals – are diagnosed in approximately 4,700 women in the United States each year. While many patients can be cured by a combination of surgery, chemotherapy, and radiation therapy, others – particularly those whose cancer has metastasized to other […]

March 18, 2014
3
Cancer research , Care for adults , Lymphomas , Treatments and Procedures
Clinical Trials and the Future of Lymphoma Treatment

Current lymphoma therapies are a far cry from the mustard gas used more than 50 years ago. More treatment options, including ones that may be more effective and less toxic, are being studied in ongoing clinical trials. “Clinical trials really are the future of lymphoma treatment,” says Ann LaCasce, MD, […]

November 14, 2013
1
Cancer research , Treatments and Procedures
Clinical Trials for Cancer Patients

By Ian Krop, MD, PhD Clinical trials are scientific studies in which new treatments – drugs, diagnostic procedures, and other therapies – are tested in people to find out if they are safe and effective. Nearly all cancer drugs in use today were tested in clinical trials.

June 10, 2013
4
Cancer research
How Do I Find The Right Clinical Trial For Me?

Clinical trials are research studies that explore whether new treatments, diagnostic techniques, or disease-prevention strategies are safe and effective in patients. They may be an option when patients no longer benefit from standard therapies. They may also offer an alternative to standard therapies, particularly if the agent being tested is […]

January 17, 2017
0
Care for adults , Ovarian cancer , Patient Stories, Adult , Treatments and Procedures
Clinical Trial Helps Betsy Brauser Live with Ovarian Cancer

As researchers and clinicians in the Susan F. Smith Center for Women’s Cancers at Dana-Farber continue studying the benefits of a two-drug combination in slowing progression of recurrent ovarian cancer, one patient is as a beacon of hope for her caregivers – and for others facing the disease. Betsy Brauser, […]

July 7, 2016
0
Cancer research , Care for adults , Patient Stories, Adult
Individualized Clinical Trial Gives Patient with Rare Cancer Time to Celebrate

Kerri Antonuccio marked her 40th birthday this spring with a fresh lease on life. For the first time since 2012, she didn’t feel too sick from cancer treatment to enjoy her big day. She was also able to travel to Mexico and serve as matron of honor at her sister’s […]

June 20, 2016
2
Care for adults , Metastatic breast cancer , Treatments and Procedures
Choosing a Clinical Trial for Metastatic Breast Cancer

When facing a diagnosis of metastatic breast cancer, patients often have many questions about clinical trials: Is a clinical trial right for me? When is a good time to consider a clinical trial? What types of treatments might be available? While there may be many questions about the process, the […]

June 9, 2016
0
Care for adults , Treatments and Procedures
Can Cancer Patients Participate in More Than One Clinical Trial at a Time?

Clinical trials are a key part of medical science’s effort to improve treatments for cancer patients. There are a variety of different types of trials, including therapeutic clinical trials, which test the safety and effectiveness of potential new agents in patients. Some patients participate in several therapeutic clinical trials, in […]

December 22, 2015
0
Cancer research , Care for adults , Patient Stories, Adult
What Is It Like to Enroll in a Clinical Trial?

When Elizabeth Cahn was presented with her treatment options for triple-negative breast cancer, the decision was about more than just getting healthy; it was about “paying it forward.” “I know there are many people who participated in clinical trials before I came along and it was because of their participation […]

March 31, 2015
1
Cancer research , Treatments and Procedures
What is a Phase I Clinical Trial?

Nearly all cancer drugs in use today were developed through clinical trials. But before they are approved for use, they must go through multiple phases designed to test the drug’s safety and efficacy. These phases include preclinical, phase I, II, and III. In phase I clinical trials, investigators evaluate how […]

June 6, 2014
2
Research
What is CRISPR and How Can It Help Cancer Research?

CRISPR, a powerful new tool for editing the DNA instruction manual in animals and humans, is proving a boon to cancer research. Scientists say CRISPR has dramatically accelerated the process of making animal models of cancer and is speeding the search for new molecular targets for cancer drugs. The technique […]

November 17, 2017
0
Cancer Genetics , Immunotherapy , Precision Cancer Medicine
Treating Cancer by Location or Genetic Markers: Which is Better?

In the past, treating cancers involved classifying them primarily by the organ or tissue where they arose – like the skin, the lungs, the breast, or the colon. Today, it’s often possible to identify the genes and proteins responsible for a tumor’s growth, and, in some cases, to offer a […]

November 13, 2017
0
CAR T-cell therapy , Leukemias , Lymphomas , Multiple Myeloma
CAR T-Cell Therapy: Is It Right For You?

CAR T-cell therapy is a cancer treatment in which a patient’s immune system T cells are genetically modified to mount a more effective attack on cancer. To date, the therapy has been approved by the U.S. Food and Drug Administration (FDA) as standard therapy for just two groups of patients. […]

November 7, 2017
0
Bladder cancer , Breast cancer , CAR T-cell therapy , Childhood , Colon Cancer , Hodgkin lymphoma , Immunotherapy , Kidney cancer , Liver cancer , Melanoma , Prostate cancer
Cancer Treatment: A Look at How It Has Evolved in 70 Years

In 1947, when Dana-Farber Cancer Institute founder Sidney Farber, MD, set out to find a drug treatment for childhood leukemia, cancer treatment took two forms – surgery to cut out cancerous masses, and radiation therapy to burn them out. Cancers that couldn’t be removed or irradiated – either because of their […]

November 3, 2017
0
Childhood , Precision Cancer Medicine
MATCHing Precision Medicine to All Kids With Cancer

This originally appeared on Vector, Boston Children’s Hospital’s blog. A multi-center clinical trial is now offering nationwide genetic profiling services to pediatric and young adult cancer patients across the U.S. The goal is to identify gene mutations that can be individually matched with targeted drugs. “This is the first-ever nationwide […]

November 1, 2017
0
CAR T-cell therapy , Lymphomas
CAR T-Cell Therapy for Lymphoma: What You Need to Know

CAR T-cell therapy, like all forms of cancer immunotherapy, seeks to sharpen and strengthen the immune system’s inherent cancer-fighting powers. It involves treating patients with modified versions of their own immune system T cells ­– white blood cells that help protect the body from disease. The groundbreaking therapy recently became […]

October 30, 2017
0
Metastatic breast cancer
Living Well with Metastatic Breast Cancer

In early 2015, Kim Delling had put her 2009 bout with breast cancer behind her. Then, at a routine checkup, her doctor ordered an additional test. “I knew something was up,” recalls Delling, a 50-year-old real estate agent in Wilmington, Mass. The cancer had come back. It had spread to her lungs, […]

October 27, 2017
0
Breast cancer , Immunotherapy
What’s New in Immunotherapy and Breast Cancer?

Immunotherapy refers to treatments that use the body’s own immune system to combat diseases. While no immunotherapy drugs are currently approved for breast cancer, clinical trials at Dana-Farber and elsewhere are exploring the effectiveness of these drugs — and whether they could work in combination with other cancer therapies. “I […]

October 26, 2017
0
CAR T-cell therapy , Non-Hodgkin lymphoma
FDA Approves CAR T-Cell Therapy for Non-Hodgkin Lymphoma

A drug called Axicabtagene ciloleucel (KTE-C19) has become the first chimeric antigen receptor (CAR) T-cell therapy approved to treat a form of cancer in adults, the Food and Drug Administration (FDA) announced today. The decision means the drug, known as Yescarta, can now be used for some adults with refractory aggressive non-Hodgkin lymphoma […]

October 18, 2017
0
Cancer research , Endometrial (Uterine) cancer
Human Touch Surgeries, New Therapies Brighten the Picture in Endometrial Cancer

Although she had been fully prepped on what to expect, Barbara Losordo was a bit surprised at the ease and speed of her recovery from surgery for endometrial cancer. Discharged from the hospital the same day she had undergone the procedure, she needed no pain medication afterward. Within a week, she […]

1
Metastatic breast cancer
How Radiation Therapy Can Help in Metastatic Breast Cancer

When breast cancer spreads beyond the breast to other parts of the body, such as the bones, brain, and/or other organs, it is called metastatic breast cancer. Depending on their location, metastatic cancer growths can cause pain and neurologic symptoms such as numbness and weakness. Patients with metastatic breast cancer, […]

October 12, 2017
0
Brain tumors , Immunotherapy
What’s New in Immunotherapy for Brain Tumors?

Vaccines, drugs, and modified human cells that activate the immune system against cancer have improved outcomes and prolonged lives in some types of cancer in the past few years. For patients with glioblastoma, the most common primary brain tumor in adults, immunotherapy has shown some promise in clinical trials — […]

October 6, 2017
0
Prostate cancer
Can Immunotherapy Be Used to Treat Prostate Cancer?

Prostate cancer can be treated by immunotherapy, and it was the first form of cancer for which a vaccine therapy – a treatment that stimulates the immune system to attack a disease – was approved by the U.S. Food and Drug Administration (FDA). That vaccine, called Provenge, was cleared by the […]

September 27, 2017
0
Breast cancer , Patient Stories, Adult
Breast Cancer Patient is a One Woman Show – In More Ways Than One

“The jig is up.” At least, that’s what Christine Ernst thought as she waited for the mammogram technician to deliver the bad news that she knew was coming. What Ernst didn’t know was what exactly that bad news would be, but eventually it became clear: she had stage II HER2-positive […]

September 22, 2017
0
Ovarian cancer , Patient Stories, Adult
Advanced Ovarian Cancer: 4 Things to Know

By Linda Dzobiek I have been living with ovarian cancer for 13 years. I was diagnosed at age 53 with Stage 3C ovarian cancer, and after receiving care near my home in Providence, Rhode Island, my doctor referred me to Dana-Farber’s Susan F. Smith Center for Women’s Cancers for a […]

September 21, 2017
2
CAR T-cell therapy , Patient Stories, Adult , Research
CAR T-Cell Therapy Gives Cancer Patients New Hope

Judy Wilkins tried four different chemotherapy regiments over 18 grueling months to try to put her lymphoma into remission. Her team never could. But thanks to CAR T-cell therapy, an emerging immunotherapy treatment that is showing great promise in clinical trials nationwide, Wilkins is cancer-free. CAR (Chimeric Antigen Receptor) T-cell therapy […]

September 19, 2017
1
Immunotherapy , Lymphomas
How is Immunotherapy Used to Treat Lymphoma?

While new types of immunotherapy are being used to treat a wide variety of cancers, immunotherapy has been a front-line treatment for lymphoma for decades. Lymphoma occurs when white blood cells known as lymphocytes grow abnormally. There are nearly 70 subtypes of Hodgkin lymphoma and non-Hodgkin lymphoma that have been […]

September 14, 2017
0
Immunotherapy , Ovarian cancer , Uncategorized
Ovarian Cancer and Immunotherapy: An Update

Immunotherapy has revolutionized the treatment of many types of cancer and is now undergoing testing in ovarian cancer. Clinical trials of drugs known as immune checkpoint inhibitors, which can unleash a potent immune system attack on cancer cells, have produced remissions in about 10-15 percent of patients with advanced and […]

September 8, 2017
0
CAR T-cell therapy , Stem cell/Bone marrow transplant
Stem Cell Transplants and Cellular Therapies: What’s the Difference?

Donor stem cell transplants and other cellular therapies are treatment approaches that harness the immune system to fight cancer using cells from the patient or from healthy donors. Stem cell transplants are used to treat blood-related cancers such as leukemia, lymphoma, and multiple myeloma, as well as certain non-cancerous blood […]

September 7, 2017
0
CAR T-cell therapy , Leukemias, childhood
FDA Gives First-Ever Approval to CAR T-Cell Therapy

The Food and Drug Administration (FDA) announced today that a drug called CTL019 has become the first chimeric antigen receptor (CAR) T-cell therapy approved to treat a form of cancer. The decision means the drug can be used as standard therapy for the treatment of pediatric and young adult patients with […]

August 30, 2017
0
Colon Cancer , Diet and Nutrition
Vitamin D: Can It Prevent or Slow Cancer?

Vitamin D may prevent or slow some types of cancer, according to some intriguing studies. However, the evidence is not yet definitive, and no recommendations currently exist on taking extra vitamin D to prevent cancer. Vitamin D is a nutrient that helps the body use calcium and phosphorus to build […]

August 29, 2017
0
Breast cancer , Young women with breast cancer
Cancer-Free Triple Negative Breast Cancer Patient Looks to Future

Kristen Collins was 40 years old when she was diagnosed with triple negative breast cancer – the most difficult type of breast cancer to treat. It was a heart-wrenching moment for Collins, who is the mother of three small children. “My heart sank when I heard the news,” said Collins. […]

August 25, 2017
0
Chemotherapy
Biological Therapy and Chemotherapy: What Are the Differences?

Chemotherapy and biotherapy are both used to destroy cancer cells. So how are they different, and how are they similar? Traditional chemotherapy uses chemical substances to treat cancer. Biological therapy, by contrast, uses living organisms, substances derived from organisms, or laboratory-made versions of those substances to act against cancer cells. […]

August 24, 2017
0
Acute lymphoblastic - ALL , CAR T-cell therapy , Non-Hodgkin lymphoma , Research
What Are The Side Effects of CAR T-Cell Therapy?

CAR T-cell therapy is a form of immunotherapy in which patients’ T cells are modified to become better at tracking down and destroying tumor cells. CAR T cells are made by extracting thousands of a patient’s T cells, sending them to a lab where they’re outfitted with genes and proteins […]

August 17, 2017
0
Metastatic breast cancer , Patient Stories, Adult
How to Advocate for Yourself If You Have Metastatic Breast Cancer

  By Lisa J. Frank I am a five-time cancer survivor – four times breast, one time melanoma – and a patient at the Susan F. Smith Center for Women’s Cancers. I am also a full-time practicing attorney who is living life to the fullest with stage IV breast cancer […]

August 10, 2017
1
Immunotherapy , Uncategorized
Cancer Immunotherapy: Taking Aim with Neoantigens

It’s a compelling idea that has attracted scientists for decades: rather than poison tumors with chemicals and radiation, use a biological agent – a vaccine – to rally the body’s formidable immune defenders to kill cancer cells and shrink tumors. Yet, even as other forms of immunotherapy are showing promise […]

August 9, 2017
0
Breast cancer
The Latest in Triple Negative Breast Cancer [Webchat]

Triple-negative breast cancer (TNBC), which makes up about 10 to 15 percent of all breast cancers, describes breast cancer cells that do not have estrogen, progesterone, or HER2 receptors. In a recent Facebook Live webchat, Ann Partridge, MD, MPH, Director of the Program for Young Women with Breast Cancer in the Susan […]

August 7, 2017
0
Head and Neck Cancer , Patient Stories, Adult
Why I Walk: David Frank, MD, PhD

It has become a fall tradition in New England: thousands of people walking up to 26.2 miles in the Boston Marathon® Jimmy Fund Walk presented by Hyundai. Their ages, backgrounds, and circumstances vary, but all take to the course with a common goal: a world without cancer. One of them […]

July 26, 2017
0
General interest
Deciding to Make a Change in Cancer Treatment

The first treatment a patient receives for cancer is generally the one his or her oncologist believes has the best chance of curing the disease or holding it in check. But the time may come when it may be appropriate to make a change in the therapy. In the best […]

July 24, 2017
1
Stomach (Gastric) cancer
Volunteering at Pan-Mass Challenge Means Family and Fun for Stomach Cancer Survivor

Saul Heller has been a professional singer and a cantor, a grocer, travel agent, and even an activist blogger. These days, however, the 88-year-old grandfather is especially proud of two new roles: stomach cancer survivor and Pan-Mass Challenge (PMC) volunteer. Each August for 12 years – missing only the summer after his January 2014 […]

July 21, 2017
0
Ask the Nutritionist , General interest , Risk and Prevention
Can Antioxidants Prevent Cancer?

Antioxidants are substances that can help protect cells from damage caused by free radicals, or unstable molecules. That damage, called “oxidative stress,” is linked to the kind of damage in DNA mutations that can contribute to the risk of certain cancers, as well as diabetes, Alzheimer’s disease, and Parkinson’s disease. […]

July 20, 2017
0
Care for adults
What Is Brain Metastasis and How Is It Treated?

When cancer spreads from its original site to the brain, it’s known as brain metastasis. While a significant percentage of all patients with cancer develop brain metastases, the most common cancers to spread to the brain are lung, breast, melanoma, colon, and kidney tumors. Every year, an estimated 100,000-400,000 people […]

July 17, 2017
0
Care for adults , Colon Cancer , Rectal cancer
How Is Immunotherapy Used to Treat Colorectal Cancer?

Cancers of the colon and rectum haven’t yet been as effectively treated with immunotherapy as have melanoma and lung cancer, but researchers are increasingly identifying patients who do appear to benefit from the immunity-boosting drugs – and devising strategies they hope will expand the reach of immunotherapy in colorectal cancers. […]

July 14, 2017
0
Cancer research , Melanoma , Skin cancers (non-melanoma)
New Tanning Drug Could Protect Skin From the Sun

Scientists may have figured out a way to let people tan safely – without involving the sun. In an effort to further develop preventative measures for skin cancers like melanoma, researchers from Dana-Farber and other health care organizations have developed a potential topical cream that stimulates skin cells to produce […]

July 10, 2017
3
Immunotherapy
Who Should Be Treated with Immunotherapy?

There has been much excitement in recent years around new drugs that exploit the power of the body’s immune system to fight cancer. In some patients, even with advanced cancers, these immunotherapy treatments have slowed or halted the disease after standard treatments no longer worked, with remissions lasting several years […]

July 6, 2017
0
Cancer research , Immunotherapy
What’s New in Treatment of Adult Histiocytic Disorders?

While blood cancers known as adult histiocytic disorders are very rare and many patients do well with today’s treatments, researchers are working to improve outcomes with therapies targeted to newly discovered mutations – and they are about to begin testing immunotherapies, too. Histiocytic disorders involved overproduction of immune white cells, […]

June 29, 2017
0
Cancer research , Immunotherapy
In Check: Attacking Cancer from Many Fronts

As a pediatric dentist, Jay Schwab had a clear-cut enemy: dental disease in children and adolescents, and the apprehensions they faced in the dental environment. Cavities could neither hide from his drill nor fool his X-ray machine, and plaque could easily be scraped away. Generations of patients went away smiling […]

June 27, 2017
0
Cancer research , CAR T-cell therapy , Immunotherapy , Research
Catch Me if You Can: Finding Cancer Cells that Hide in Plain Sight

In the high-stakes contest of hide-and-seek between cancer cells and the human immune system, the advantage doesn’t always lie with the body’s defenders. A new approach to treatment, known as CAR T-cell therapy, may shift that balance of power. Cancer cells conceal themselves from the immune system not by barricading […]

June 21, 2017
0
Care for children
College Student Reconnects with the Oncologist Who Saved Her Life

This post originally appeared on Thriving, the Boston Children’s Hospital blog. Anna Protsiou was 5 when she was diagnosed with neuroblastoma in 2002. She remembers pain, and fruit-scented anesthesia masks that led her to stop eating cherries. She also remembers hospital arts and crafts projects. What she barely remembers is […]

June 20, 2017
0
Care for adults
What Is Chronic GVHD and How Can I Manage It?

Chronic graft-versus-host disease (GVHD) is a common and potentially life-threatening complication of stem cell transplants that use donor cells. It arises when the donor’s immune system cells treat the recipient’s body as foreign and raise an attack on certain organs and tissues, most often the skin, mouth, and eyes. The […]

June 15, 2017
0
Cancer research , Care for children
An Unclassified Tumor — with a Precisely Targeted Therapy

Early last year, at his home in San Juan, Puerto Rico, Jesus Apolinaris Cruz’s leg hurt so much he could barely sleep. “All day, it was constant pain,” the 13-year-old recalls. His parents took him to two local pediatricians, who examined him, drew blood, and tested his platelets. No diagnosis. […]

June 6, 2017
0
Cancer research , CAR T-cell therapy , General interest
CAR T-Cell Therapy: How Does It Work?

CAR T-cell therapy is a kind of cellular therapy, which uses a patient’s own immune system cells to rally an attack on cancer. They’re made by removing a specific set of cells from the blood, modifying them in a lab to intensify the immune system’s natural response to cancer, and […]

June 2, 2017
2
Brain tumors , Brain tumors, childhood , Immunotherapy , Research
Webchat: The Latest in Brain Tumor Research and Care

In honor of Brain Tumor Awareness Month, David Reardon, MD, and Patrick Wen, MD, of Dana-Farber’s Center for Neuro-Oncology, went live on Facebook to answer questions about brain cancer. The doctors discussed advice for brain tumor patients, answered audience questions, and described the difference between the two major categories of […]

May 26, 2017
0
Bladder cancer , Genitourinary Cancer , Immunotherapy
What Are the Symptoms of Bladder Cancer?

Bladder cancer accounts for only five percent of new cancer cases in America – a small piece of the pie – but considering it is the fourth most common cancer in men, it is important to be aware of the signs and symptoms of this disease. The most common sign […]

May 24, 2017
0
Immunotherapy , Research
What Is a PD-L1 Test?

A PD-L1 test helps doctors determine whether a patient is likely to benefit from cancer drugs known as immune checkpoint inhibitors. It involves sending a piece of tumor tissue to a lab for analysis. PD-L1 is a protein that allows some cells to escape an attack by the immune system. Extending […]

May 22, 2017
2
Treatments and Procedures
Who Are the Different Nurses on a Cancer Care Team?

Nurses play a critical role in caring for cancer patients. From administering therapies and managing side effects, to preparing patients and families for what to expect, they are often the providers who patients see the most. And because of the range of services they provide, there are often multiple nurses […]

May 12, 2017
0
Cancer research , General interest , Immunotherapy
The Progress of Cancer Immunotherapy: The Tip of the Iceberg

If the human immune system was a powerful racing car, you could say that scientists in the past few years have gained unprecedented control over how to make it accelerate, and what causes it to slow or stop. This knowledge has spawned new immunotherapy drugs that are delivering dramatic benefits […]

May 9, 2017
2
Blood disorders, childhood , Cancer research , Patient Stories, Pediatric
How Pediatric and Canine Cancer Similarities Can Help Both Children and Pets

In March 2016, Ollie the pug, a therapy dog at Boston Children’s Hospital, paid a bedside visit to 7-year-old Carter Mock. Both dog and boy lost limbs to osteosarcoma, a cancer of the bone. Ollie’s left front leg was amputated at the shoulder. After removing the tumor in Carter’s left […]

May 2, 2017
0
Cancer research , Care for adults , Head and Neck Cancer , Immunotherapy
What’s New in Immunotherapy for Head and Neck Cancer?

For patients with advanced head and neck cancers, immune-based therapies have started to show results against these hard-to-treat tumors. Two immunotherapy drugs were approved in 2016 for use when standard treatments failed, and many other agents are being tested in clinical trials. Immunotherapies work by enhancing the body’s natural defenses […]

April 20, 2017
0
Cancer research , Multiple Myeloma
What’s New in Multiple Myeloma? [Webchat]

In a recent Facebook Live webchat, Jacob Laubach, MD, MPP, Clinical Director of the Jerome Lipper Multiple Myeloma Center, discussed the different ways that patients can be treated with multiple myeloma, as well as exciting avenues of treatment, such as combination therapy.

April 4, 2017
2
Cancer research , Immunotherapy , Kidney cancer
What’s New in Immunotherapy for Kidney Cancer?

Kidney cancer is one of several cancers that has responded well to immunotherapy drugs, which can free the immune system from restraints that cancer cells can impose on it. The drug nivolumab (Opdivo), for example, which was recently approved, can extend survival in patients with metastatic kidney cancer after other […]

March 23, 2017
0
Care for adults , Kidney cancer
What Is Kidney Cancer?

Kidney cancer, or renal cancer, is a form of cancer in which cancer cells grow in the tissues of the kidneys. These two bean-shaped organs, located on each side of the body above the waist, are responsible for filtering and cleaning blood, removing waste, and producing urine. Kidney cancer generally […]

March 15, 2017
0
Biliary cancer , Gastrointestinal Cancer , General interest
What Is Biliary Cancer?

Biliary cancer is a form of cancer that develops in the bile duct system, which connects the liver, gallbladder, and small intestine, moving bile – a fluid that helps digest fats – to the small intestine. While relatively uncommon, approximately 15,000 people in the United States are diagnosed with this […]

February 10, 2017
0
Cancer research , Immunotherapy , Research
Can a Serum Biomarker Predict Response to Immunotherapy?

This post originally appeared on Cancer Research Catalyst, a blog from the American Association of Cancer Research (AACR). By Srivani Ravoori, PhD Immunotherapy, particularly a class of immunotherapeutics called immune checkpoint inhibitors, has transformed the treatment of several types of cancer in recent years. So far, the U.S. Food and […]

January 26, 2017
1
Cancer research , Immunotherapy , Precision Cancer Medicine , Research , Risk and Prevention
Experts Forecast Cancer Research and Treatment Advances in 2017

This post originally appeared on Cancer Research Catalyst, the official blog of the American Association for Cancer Research. It was originally published Jan. 10, 2017. By Srivani Ravoori, PhD As we step into 2017, a big question looming in the minds of all stakeholders in the cancer research arena is: […]

January 10, 2017
0
General interest , Research , Stem cell/Bone marrow transplant
What is Haploidentical Stem Cell Transplantation?

A treatment for patients with blood-related cancers and certain blood disorders, stem cell transplantation involves replacing a patient’s unhealthy blood-forming cells with healthy ones. Patients are first treated with chemotherapy, and sometimes radiation therapy, to wipe out or diminish the bone marrow and lymph nodes where cancers such as leukemia […]

January 9, 2017
0
Cancer research , General interest
21st Century Cures Act Will Support ‘Revolutionary’ Cancer Research

On Dec. 13, President Barack Obama signed into law the 21st Century Cures Act, legislation that includes significant funding to the National Institutes of Health (NIH) to further the Beau Biden Cancer Moonshot, and to the Food and Drug Administration (FDA) to speed the drug approval process. Laurie Glimcher, MD, […]

December 14, 2016
0
Brain tumors, childhood , Care for children , Patient Stories, Pediatric , Uncategorized
Pediatric Brain Tumor Patients Find Success with Targeted Drug

  At first, early intervention specialists told Christi Powers that her young son’s gross motor delays and poor balance were likely the result of weak muscle tone, but when Danny developed severe headaches at age 4, she took him to the emergency room. Soon the suburban Boston boy was diagnosed […]

December 13, 2016
0
Cancer research , Ovarian cancer , Treatments and Procedures
Drug Prolongs Remissions in Some Relapsed Ovarian Cancers

Ed. note: Niraparib (Zejula) was approved by the U.S. Food and Drug Administration (FDA) on March 28, 2017, as a maintenance therapy for women with ovarian, fallopian tube, or primary peritoneal cancer. This post was originally published on Oct. 21, 2016. For women with relapsed ovarian cancer that responds to platinum-based […]

October 21, 2016
0
Care for adults , Non-small cell lung cancer , Small cell lung cancer
What is the Difference Between Small Cell and Non-Small Cell Lung Cancer?

Lung cancer is divided into two general categories based on its appearance under the microscope: small cell and non-small cell. Non-small cell is the more common type and currently accounts for about 87 percent of lung cancers. Doctors make a distinction between the two types of lung cancers because treatment […]

October 7, 2016
0
Breast cancer , Care for adults , Treatments and Procedures
Breast Cancer: When is Less Treatment Better?

By Eric Winer, MD When a woman learns she has breast cancer, and she has cancer treatment available to her, it is only natural that she and her doctor would choose a powerful course of action. And in many cases, this approach makes sense. However, aggressive treatments often come with […]

October 3, 2016
3
Cancer research , Ovarian cancer
Ovarian Cancer: State of the Science

By Ursula Matulonis, MD This is an exciting time for those of us engaged in research and patient care for ovarian cancer. As we’ve learned more about this cancer – its early formation, molecular machinery, and the body’s defenses against it – we’ve also come to understand its weaknesses. An […]

September 29, 2016
0
Cancer research , Immunotherapy , Research
What’s New in Cancer Immunotherapy?

Keeping up with progress in the field of cancer immunotherapy requires paying close attention. The number of approved drugs that help the body’s immune system fight cancer continues to grow, as does the list of different cancers in which immunotherapy is proving effective – in some cases yielding dramatically longer-lasting […]

September 27, 2016
0
Blood Cancer , Care for adults
What Are the Most Common Blood Cancers in Adults?

Someone in the United States is diagnosed with a blood cancer every three minutes. The most commonly diagnosed blood cancers are non-Hodgkin lymphoma, chronic lymphocytic leukemia, acute myeloid leukemia, acute lymphoblastic leukemia, and multiple myeloma.   Non-Hodgkin Lymphoma   Non-Hodgkin lymphoma (NHL) is a type of cancer that forms in […]

September 19, 2016
0
Care for adults , Chemotherapy , Research , Treatments and Procedures
Can Marijuana Benefit Cancer Patients?

Marijuana occupies a complicated position among the substances used to alleviate symptoms associated with cancer and cancer treatment. On the one hand, nearly half of U.S. states, mostly in the far west, northeast, and upper midwest, have legalized Cannabis (the plant from which marijuana is derived) for medical purposes. Others […]

September 14, 2016
0
Care for children , Ewing sarcoma
What Is Ewing Sarcoma?

Ewing sarcoma is a cancer that grows in the bones and soft tissues, usually in the thigh or pelvis. It is most common in children and young adults between the ages of 5 and 20, and more common in boys than girls. Although most patients are teenagers, Ewing sarcoma can […]

August 31, 2016
0
Podcasts , Prostate cancer , Research , Treatments and Procedures
Cancer Conversations Podcast—Episode #16: The Latest in Prostate Cancer Treatment and Research

Prostate cancer affects 230,000 men each year. Although diagnoses are increasing worldwide, most people die with prostate cancer and not of prostate cancer, according to Mark Pomerantz, MD, a medical oncologist in Dana-Farber’s Lank Center for Genitourinary Oncology. In this Cancer Conversations podcast episode, Pomerantz discusses genetics, risk factors, and […]

August 26, 2016
0

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