An ovarian cyst is not the same as ovarian cancer. Benign ovarian cysts are extremely common, while ovarian cancer is rare. They do share symptoms, such as abdominal bloating, pressure, pain, or swelling. A gynecologist can help you determine if you have a benign ovarian cyst and if you need treatment. Many cysts go away … Read more
The same way you can predict whether a family is away, getting ready for work, or cooking dinner by observing which lights are on in the house, scientists can gaze into a cell and predict its state based on which genes are on or off. Normal liver cells, for instance, have a predictable and recognizable … Read more
Results of several phase 3 trials and dozens of other studies led by Dana-Farber researchers were presented online and in person June 3-7 at the 2022 Annual Meeting of the American Society of Clinical Oncology (ASCO), the world’s largest clinical cancer research meeting. Some of the research reports presented by Dana-Farber investigators include: Improved progression-free … Read more
Scientists are beginning to make inroads into treating cholangiocarcinoma, a rare, lethal cancer of the bile ducts, with precision drugs. Last year, the first targeted drug for some patients with the disease was approved. Now, Dana-Farber scientists say they have identified another genetic alteration in a small percentage of cholangiocarcinoma patients that can be attacked … Read more
Khiem Tran’s response to drug therapy for advanced colorectal cancer seemed to defy the severity of his disease. After just a few doses of chemotherapy and a targeted drug, the cancer, which had spread from his rectum to his liver, was in full retreat, with a key marker of tumor burden dropping from stratospheric levels … Read more
As one of three family members with the same first and last name, John E. Duggan found individuality through initials while growing up — becoming universally known as “Jed.” Having survived both stage III colon cancer and thyroid cancer before age 30, he is refusing to let another familial tie get him down. Duggan has MUTYH-associated polyposis (or MAP), … Read more
It was a decade that began with the electrifying results of a clinical trial for a revolutionary new cancer therapy and ended with a Nobel Prize in Medicine for very different cancer-related research. In between those dramatic bookends, the 2010s were packed with progress, with discoveries leading to the FDA’s 2017 approval of the first … Read more
Medically reviewed by Jeffrey A. Meyerhardt, MD, MPH Colorectal cancer forms in the tissues of the colon or rectum, which make up the large intestine. The colon and rectum are part of the body’s digestive system, which is made up of the esophagus, stomach, and the small and large intestines. The first six feet of … Read more
Genetic testing provided a father and son with a proper diagnosis for their rare colon condition.
There are a number of steps people can take to reduce their risk of colon cancer, including screening and adjustments in diet and lifestyle.
Studies show that men are often less likely than women to keep up with regular doctor’s visits, or be honest about their symptoms, which may contribute to worse health outcomes. Learn More: Make an Appointment at Dana-Farber What is Genetic Testing? Being vigilant about health care screenings is one of the best things you can … Read more
Most cases of pancreatic cancer develop for unknown reasons, but about 10 percent occur in families that have a strong history of the disease. That doesn’t mean that if you are a member of such a family you will develop pancreatic cancer, but rather that you are at a higher risk for it. “Research has … Read more
As with many cancers, screening is a crucial step in preventing colorectal cancer. In fact, colorectal cancer is one of the most treatable forms of cancer if it is found early. “There are many different ways we can prevent colorectal cancer, ranging from medical tests to dietary and lifestyle behaviors, to taking certain medications,” says … Read more
Updated April 13, 2015 While one of the most common cancers in both men and women, colorectal cancer remains a very preventable disease, says Jeffrey Meyerhardt, MD, MPH, clinical director of Dana-Farber’s Center for Gastrointestinal Oncology. “Most of these cancers develop over a period of years,” he says. “While not preventable in everyone, the earlier … Read more
By Christine Hensel Triantos On a cold winter day in 2002, Sharon Goyette stepped into Dana-Farber’s Center for Cancer Genetics and Prevention. She was a 21-year-old college student, and this was the last place she wanted to be. But her mother had insisted. After developing colon cancer, Goyette’s mother had been diagnosed with Lynch syndrome … Read more
Mimi Gallagher never missed a gynecologist appointment. Her maternal grandmother died from ovarian cancer in her early 70s, and Gallagher, at 46, was well aware of her risk. Despite her diligence, and years of worry-free trips to the gynecologist, the mother of two was diagnosed with stage III c ovarian cancer. Troubling symptoms in July … Read more
Medically reviewed by Peter C. Enzinger, MD Although not a common type of cancer in the United States, stomach (gastric) cancer is the second leading cancer death worldwide, and affects more men than women. “The United States’ risk is much less because of hygiene and the safety of foods we eat, and more to do … Read more
If the new era of “targeted” cancer drugs and personalized treatments for patients realizes its promise, the power of genomics will get a lot of the credit. Genomics is one of the most commonly heard terms in cancer research and biotech companies today – but what does it really mean? What is genomics? Most people … Read more
For a while, Stephanie Dobson attributed her gastrointestinal issues to her pregnancy. It was her second, a girl born in May 2023, a baby sister to her son. But when the symptoms persisted for the 34-year-old mother, she raised the issue with her primary care provider. She was encouraged to see a gastroenterologist. On an … Read more
Breast cancer survivor Jennifer Perry is at high risk of additional cancers during her lifetime because she carries an inherited mutation for Li-Fraumeni syndrome (LFS). But experts at the new Li-Fraumeni Syndrome and TP53+ Center at Dana-Farber Cancer Institute can help her manage that risk. While there is no treatment for LFS — a familial … Read more