David Trueblood’s long career in journalism was shaped by new technology, including the rise of digital photography and the impact of online media. So, upon learning in early 2023 that he would need a stem cell transplant due to myelodysplastic syndrome (MDS), a rare blood disorder impacting his bone marrow, Trueblood appreciated the role innovation … Read more
In most ways, Bill Ross’s stem cell transplant for multiple myeloma at Dana-Farber Brigham Cancer Center (DFBCC) wasn’t out of the ordinary. He received chemotherapy to destroy the tumor cells in his body and then an infusion of his own hematopoietic stem cells, which flocked to his bone marrow and regenerated his blood supply. Over … Read more
Stem cell transplants are used to treat patients with a variety of blood-related cancers. The goal of a transplant is always the same: to cure the disease or significantly extend a patient’s life. Stem cell transplants can be used in the treatment of the following cancers: Why might a patient need a stem cell transplant? … Read more
A stem cell transplant is one of the most powerful tools doctors have for treating certain kinds of cancers and blood-related diseases. The “grafted” cells involved in a transplant are known as hematopoietic stem cells, meaning they’re able to develop into all types of blood cells — red blood cells, which deliver oxygen throughout the … Read more
Stem cell transplantation refers to transplants of blood-forming stem cells taken from the bone marrow or collected from the bloodstream. Autologous transplants use the patient’s own stem cells, while allogeneic transplants use stem cells provided by a donor. Stem cell transplants offer some patients with blood-related cancers such as leukemia, lymphoma, and multiple myeloma the … Read more
For many patients with lymphoma or multiple myeloma, a stem cell transplant with their own stem cells (an autologous transplant) or CAR T-cell therapy can extend life significantly or even cure the disease. A variety of factors influence which of these two treatments is recommended, including: What is the difference between stem cell transplant and … Read more
Both allogeneic and autologous stem cell transplants involve treating a patient with chemotherapy followed by an infusion of blood-forming stem cells, with a goal of curing the cancer or extending the time before the disease relapses. In adults, transplants are used to treat a range of blood-related cancers, myelodysplastic syndromes, and non-malignant blood disorders. Autologous … Read more
By Howard Brown As the Adult Stem Cell Transplant Program at Dana-Farber celebrates its 50th anniversary, one cancer survivor whose 1990 transplant came when the procedure was far more arduous — and far less successful — reflects on his experience. I have a four-by-three-inch plastic bag that I’ve saved for more than 32 years. It’s … Read more
The views discussed in this piece do not represent the U.S. Government. Sara Minkara lost her sight at the age of seven due to juvenile macular degeneration — a rare genetic condition — but she has never allowed that to slow her down. Once she grew up, she made her life’s goal helping the world … Read more
Every year, Nancy Demers celebrates two birthdays. The first marks the day she was born: August 6, 1943. The second — March 20, 2015 — is the day the then-71-year-old Connecticut resident received a stem cell transplant at Dana-Farber Brigham Cancer Center and the start of a healthy new life. Eighteen months prior, in September … Read more
As an economist specializing in statistical analysis, Dan Rosenbaum has done everything from help the federal government use more evidence in its decision-making to assist several National Basketball Association (NBA) teams in finding and signing the best players. Research and number-crunching are his expertise, so when Rosenbaum learned he needed a life-saving stem cell transplant … Read more
For Duane Witter, the most difficult part of his cancer treatment was recovering from his stem cell transplant and having to step away from teaching and coaching high school basketball in Farmington, CT. “Before all this, I used to say that my superpower was to never miss a day of school,” he says. “Stepping away … Read more
To see Tara Daniels today, with a corporate job in marketing and about to close on a house, you’d never know what she’s been through, how thrilled she is to be alive. This month marks five years since she received a high-risk bone marrow transplant for a life-threatening blood cancer. Tara woke up feeling sick … Read more
Although stem cell transplantation is the only current therapy with the potential to cure myelodysplastic syndromes (MDS), it is rarely used as an initial treatment for older patients because it hasn’t been proven superior to other therapies. New research by Dana-Farber Cancer Institute investigators stands to overturn that practice. In a clinical trial involving 384 … Read more
Dawn MacKerron realizes it might sound strange to say that getting hit in the eye with a basketball was a blessing. But an accident on the court helped inform treatment for a rare form of lymphoma and participation in a clinical trial at Dana-Farber that set her on a cancer-free path. It all started when … Read more
Ali Mercy was an eight-year-old with relapsed acute lymphocytic leukemia (ALL) in need of a stem cell transplant. First, however, his father Abrahim had to find a country willing to provide Ali with the life-saving procedure. Transplants were not performed in the United Arab Emirates (UAE), where Abrahim and Ali lived together in the city … Read more
When Liz Bowen first learned she would need a stem cell transplant, she had no idea she’d be making history as the first outpatient stem cell transplant patient in New England. Bowen, 55, was diagnosed with cutaneous T-cell lymphoma, a rare form of skin lymphoma, in 2017. Her care team at Dana-Farber/Brigham and Women’s Cancer Center … Read more
Reduced-intensity stem cell transplants, which don’t require the traditional week-long hospital stay, are offered to qualified patients at many cancer treatment centers across the country, including Dana-Farber/Brigham and Women’s Cancer Center. These outpatient transplants (also known as ambulatory transplants) are identical in virtually every respect to those performed on an inpatient basis, with the exception … Read more
A troublesome cough led Patty Reid on a nine-months-long medical odyssey that resulted in a diagnosis of non-Hodgkin lymphoma (NHL). Just as the then-60-year-old was preparing for a stem cell transplant in late 2016, a new research discovery prompted her doctors to change the type of transplant Reid received—greatly lessening her risk for another cancer … Read more
Alan Dynner was diagnosed with acute myeloid leukemia (AML) in 2016 at 76 years old. Treatment for the cancer would require a life-saving stem cell transplant, a procedure that most hospitals deemed too grueling for someone Dynner’s age. But thanks in large part to treatment options a short drive from his Boston home at Dana-Farber/Brigham … Read more