Cancer research
Clinical Trials for Cancer Patients

By Ian Krop, MD, PhD Clinical trials are scientific studies in which new treatments – drugs, diagnostic procedures, and other therapies – are tested in people to find out if they are safe and effective. Nearly all cancer drugs in use today were tested in clinical trials.

June 10, 2013
4
Cancer research
Fertility Treatment and Cancer: Is There a Link?

By Wendy Chen, MD Dana-Farber Breast Oncology Center Susan F. Smith Center for Women’s Cancers Millions of women in the United States have sought treatment for fertility-related problems over the past 35 years. Because many of these treatments –including fertility drugs and in vitro fertilization (IVF) – use hormones to […]

June 5, 2013
2
Cancer research , Care for adults
Should You Donate Tissue for Cancer Research?

By Eric Schuller If you recently learned you have cancer, donating a sample of your cancer tissue to science is probably the last thing on your mind. But it’s a topic that you might discuss with someone on your health care team, because cancer researchers often rely on donated tissue […]

May 21, 2013
2
Cancer research , Care for children
Genetic Testing, Cancer Risk, and Angelina Jolie’s Choice

Actress Angelina Jolie is no stranger to the headlines, but she stunned the world with her Op-Ed in The New York Times, in which she shared her very private decision to have a preventive double mastectomy after testing positive for the BRCA1 gene mutation. “I hope that other women can benefit […]

May 14, 2013
5
Cancer research , Care for children
Five Reasons for Optimism about Pediatric Cancer Care and Research

By Stephen Sallan, MD Today, three quarters or more of all childhood cancer patients will be cured of their disease, a higher percentage than ever before. And the numbers will only get better as we learn more about the biology of childhood cancers and develop new ways of treating them.

May 2, 2013
0
Cancer research , Care for adults
Can Acupuncture Ease Cancer Symptoms?

by Richard Saltus One of the oldest healing practices in the world, acupuncture is beginning to have a role in alleviating pain and discomfort associated with cancer and its treatments. Acupuncturists use fine needles to penetrate the skin and stimulate – manually or electrically – specific points on the body. Stimulation […]

April 29, 2013
2
Cancer research
Turning Traditional Medicine Into Cancer Drugs

Quite a few substances used in traditional medicine in China or other countries have received Food and Drug Administration (FDA) approval as cancer drugs… and their numbers are growing.  Some examples are: Arsenic trioxide, made from arsenic sulfide ore, has been used therapeutically for more than 2,400 years. Following promising […]

April 23, 2013
1
Cancer research
Why We Need to Fund Cancer Research

One of the goals of the Rally for Medical Research, held in conjunction with the American Association for Cancer Research (AACR) 2013 Annual Meeting, earlier this month was to bring awareness to and education about the impact of the cuts in federal funding for medical research. Dana-Farber’s Kenneth C. Anderson, MD participated in the Rally. […]

April 18, 2013
1
Cancer research
Rally to Support Cancer Research Today

by Robert Levy More than 18,000 cancer scientists from around the world are in Washington, D.C., this week for the annual meeting of the American Association for Cancer Research (AACR). The meeting serves as a forum for the presentation and discussion of the latest discoveries in cancer research. The meeting […]

April 8, 2013
0
Cancer research
How Do Cancer Drugs Block Pathways?

by Richard Saltus    Cells are like young children – they need a lot of guidance on how to behave. Your body’s cells are constantly getting that help – in the form of hormones, growth factors, and other chemicals telling them when to rest, grow, duplicate their DNA, divide, or […]

March 19, 2013
1
Cancer research
Zeroing In On Dark Matter

By Richard Saltus If the human genome – the complete set of  DNA blueprints in a cell for building a human being — is truly “the book of life, ”  as it has been called, then 99 percent of life’s book is gobbledygook. Only 1 percent of the DNA contains […]

March 8, 2013
0
Cancer research
Sequestration Could Slow the Pace of Biomedical Research

By Edward J. Benz, Jr., MD The automatic budget cuts (or sequestration) that went into to effect as a result of the Budget Control Act of 2011, could have a chilling long-term effect on scientific research in the United States. The automatic cuts will slash 5.1 percent – or about […]

March 4, 2013
1
Cancer research
Cancer Researcher Values Teaching and Learning

By William Hahn, MD, PhD Every year, hundreds of postdoctoral fellows and graduate students study cancer research at Dana-Farber under some of the world’s leading scientists. The Dana-Farber Postdoc and Graduate Student Affairs Office recently named the first recipient of its Mentor-of-the-Year Award: William Hahn, MD, PhD, the Institute’s deputy […]

February 28, 2013
0
Cancer research , General interest
Managing Cancer Risk: Miss America Contestant’s Decision Puts Genetics and Cancer Center Stage

Win or lose, Miss America contestant Allyn Rose made news with her decision to undergo a double mastectomy. According to the Associated Press, Rose, who lost her mother to breast cancer, inherited a rare genetic mutation which might put her at greater risk for developing cancer. Her decision to have […]

January 12, 2013
0
Cancer research , Care for children
Pediatrics and Gene Therapy: A Conversation with David Williams

For David Williams, MD, the field of pediatrics offers two great attractions. “It is wonderful because of the kinds of patients you take care of,” he says. “But also because of the personalities of pediatricians – in pediatrics you find very compassionate and caring people.” Williams embodies that compassion and […]

January 3, 2013
0
Cancer research , Care for adults
Can Breast Cancer Patients Avoid Multiple Surgeries?

When Jane Davis was diagnosed with breast cancer last July, she began learning as much as she could about her disease. Davis quickly discovered one of the most startling statistics about breast cancer: Up to 40 percent of women who have a lumpectomy require a second surgery. That’s because surgeons often […]

January 2, 2013
4
Cancer research , Care for adults
Proton Therapy No Better Than Traditional Therapy for Prostate Cancer Patients

When it comes to treating prostate cancer, proton radiotherapy (PRT) is no better than traditional intensity-modulated radiation therapy (IMRT), according to a new study reported in the Journal of the National Cancer Institute on Friday. PRT is an advanced but expensive treatment option for some prostate cancer patients. However, the […]

December 18, 2012
0
Cancer research
Making Science Count: A Conversation with Ken Anderson

When Ken Anderson, MD, began working on multiple myeloma four decades ago, the disease, a cancer of the bone marrow, was untreatable. “People died within months,” says Anderson. Today, the story is very different. In the past decade, eight new multiple myeloma treatments have been approved. Survival has doubled. “When […]

November 29, 2012
1
Cancer research
What Evolution Can Teach Us About Cancer

Like wombats and wildebeests, cancer cells are continually adapting to their environment. If that environment includes drugs meant to kill cancer cells, some cells may adapt so well, they eventually gain the ability to grow and divide in spite of those drugs – a process known as drug resistance. The […]

November 1, 2012
1
Cancer research , Uncategorized
Why Do Scientists Use Zebrafish to Study Cancer?

Cancer scientists use a wide variety of techniques to study the growth and development of tumor cells. Laboratory research often focuses on individual cells or tissue samples, but to learn how cancers grow and respond to therapies in living organisms, scientists rely on other experimental models. In recent years, zebrafish […]

October 18, 2012
1
Cancer research , Care for adults
Doctor/patient team fight rare cancer

By Karen Lee Sobol I recently learned that the word “patient” shares a Latin root with the word “compassion.” Any one of us can become a patient, for a number of reasons. For me, hearing a diagnosis of Waldenström’s macroglobulinemia flipped a switch. I became a patient in a big way.

August 2, 2012
4
Cancer research , Care for adults , Care for children
Opening of cancer center in Rwanda is “privilege beyond words”

The dirt roads in northern Rwanda now lead to a cancer center where patients can receive care for a disease that was, until now, considered a death sentence there. The Butaro Cancer Center of Excellence, which was dedicated on July 18, has allowed Dana-Farber/Brigham and Women’s Cancer Center to extend a […]

July 19, 2012
3
Cancer research , Care for adults , Care for children
Teens and young adults overlook skin cancer risk

The call of the beach is hard to ignore on sunny summer days. Yet many teens and young adults do not follow protection tips when they hit the sand. They remain the most difficult age group to convince that ultraviolet (UV) rays, which come from the sun and indoor tanning […]

July 2, 2012
1
Cancer research , Care for adults , Health and wellness , Uncategorized
How are genes involved in cancer?

Genes don’t cause cancer, but genetic mutations can. Our cells have about 22,000 genes, which consist of DNA packed into chromosomes inside the cell nucleus. These genes control a wide range of functions, including cell growth and division. When the genes misbehave or mutate, cancer can develop.

June 28, 2012
0
Cancer research , Care for adults
Meningioma: A tumor on the edge of the brain

Musician Sheryl Crow announced on June 5 that she has a benign brain tumor known as a meningioma. Below, doctors from Dana-Farber’s Center for Neuro-Oncology describe this condition. The singer-songwriter, a breast cancer survivor, visited Dana-Farber in 2006. Meningiomas are tumors on the surface of the brain, spinal cord, and […]

June 15, 2012
3
Cancer research , Care for adults
Fact or Fiction: Symptoms of Inflammatory Breast Cancer

Inflammatory breast cancer (IBC) is a rare but aggressive form of breast cancer that affects young women more than older women.  Because it’s relatively uncommon — it represents less than five percent of all breast cancer cases — people are often confused about what inflammatory breast cancer is and how […]

June 12, 2012
4
Cancer research
What is immunotherapy for cancer?

Immunotherapy is one of the most technologically advanced yet basic forms of cancer treatment. It uses the body’s own defense mechanism, the immune system, to fight cancer. Immunotherapy is probably most familiar to you in the form of vaccinations for the flu, polio, chicken pox, and other contagious diseases. In […]

June 5, 2012
0
Cancer research
Five reasons to be optimistic about the future of cancer treatment

It’s not always easy to recognize that we live in a golden age. Too often we fail to appreciate the amazing things going on around us because we‘re so caught up in day-to-day activities and pressing demands that we presume that the extraordinary is rather ordinary. So it may be […]

May 31, 2012
2
Cancer research , Care for adults
A Life Saved by Second Opinions, Experimental Treatments, and a Touch of Luck

By James Bond “How long will I live?” I asked my oncologist in Ohio in 1992, when I was 44 and diagnosed with multiple myeloma. “Three years,” he answered. Instead, I enjoyed 10 more years of active living. Then my disease began to overtake me; my kidneys were failing, I […]

May 3, 2012
13
Cancer research , General interest
‘Encyclopedia’ charts genetics of cancer

The Encyclopedia Britannica may have published its last print edition, but a group of Dana-Farber scientists and their colleagues recently produced one of the first encyclopedias to help researchers determine which subtypes of cancer are likely to respond to current drugs. The freely available, online encyclopedia lists hundreds of cancer […]

May 1, 2012
2
Cancer research , General interest
How do genes get their names?

Chinese scientists recently found a gene that encourages the growth of a form of lung cancer by switching on a circuit that includes a gene called sonic hedgehog. How do genes get their names? When a scientist discovers a new human gene, he or she submits a proposed name to […]

April 17, 2012
0
Cancer research
Cancer research updates from AACR

The American Association for Cancer Research recently held its annual meeting in Chicago. Dr. Loren Walensky of Dana-Farber/Children’s Hospital Cancer Center talks about some of the highlights, including personalized medicine and a new grant that’s helping his team develop new technology to target cancer.

April 4, 2012
0
Cancer research , General interest
Counting cells at lightning speed

At many supermarkets, you can dump a pocketful of change into a machine that rapidly counts your coins, sorting them into pennies, nickels, dimes, and quarters and computing the total amount. Imagine something similar in a research lab. In the past, cells had to be manually studied and counted under […]

March 27, 2012
0
Cancer research , Care for adults
Men unite to cure women’s cancers

For most people, getting involved with a cause means thinking about what type of organization they’d like to support. But this is a story about what happens when a cause selects you – taps you on the shoulder and asks you to engage in battle. It began in 1998 when […]

March 20, 2012
0
Cancer research , General interest , Health and wellness
Alcohol and breast cancer: What’s the risk?

For many women who enjoy a glass of wine, research showing that relatively small amounts of alcohol can raise their risk of breast cancer are disconcerting, to say the least. And confusing, too. How much drinking is OK? Isn’t a glass of red wine a day good for your heart […]

March 15, 2012
7
Cancer research , Care for adults , Health and wellness
Specialists recommend regular colonoscopies

If you’re over 50, have you been screened for colorectal cancer?  If not, the month of March would be a great time to talk about screening with your doctor. Colorectal cancer is the third leading cause of cancer in men and women in theUnited States. In 2012, an estimated 141,210 […]

March 6, 2012
0
Cancer research
From old drugs, new cancer treatments

When it comes to finding better drugs for cancer, Dana-Farber oncologist Dr. David Frank is not a patient man. While new cancer science promises to bring novel, improved therapies to the bedside, it can take many years — and Frank isn’t willing to wait. “We need to get new treatments […]

March 1, 2012
0
Cancer research , Care for adults , General interest
When Doctors Encounter Diseases without Names

The complicated meaty machine that is the human body can break down in a remarkable variety of ways. The 9th edition of the International Classification of Diseases (ICD-9) includes more than 16,000 afflictions – everything from the bite of a venomous tropical millipede to injury by falling spacecraft debris. With all […]

January 31, 2012
0
Cancer research , Care for children
Genetic counseling now recommended for children with sarcoma

If your son or daughter has been diagnosed with a type of sarcoma – a tumor in connective tissue like muscles or bones – there are many questions: Will my child make a full recovery? What are the immediate and long-term side effects of treatment? Most parents don’t consider whether […]

January 26, 2012
5
Cancer research
The most talked about cancer stories of 2011

The face of cancer care in 2011 changed in encouraging and – in some cases – challenging ways. Here are some of the cancer stories that captured the most press attention in 2011.  A federal task force recommended against routine testing of healthy men for the prostate-specific antigen (PSA), which […]

January 24, 2012
0
Cancer research , General interest , Health and wellness
Obesity and cancer: What’s the link?

There are a lot of good reasons not to gain too much weight, but you might not be aware of this one: Growing evidence links obesity to a higher risk of developing cancer, and being overweight may worsen a cancer patient’s outlook. Although more and more studies are finding this […]

January 12, 2012
0
Cancer research , General interest
Dana-Farber’s Cancer Vaccine Center-Do Viruses Cause Cancer?

In 1958, when scientists linked an aggressive form of leukemia to infection with a particular virus, some researchers took the discovery as evidence that nearly all cancers are caused by viruses. A cover story in Life magazine in 1962 proclaimed, “Cancer may be infectious.” Today, it is estimated that viruses […]

December 29, 2011
0
Cancer research , Care for adults , Health and wellness
The benefits of vitamin D

Activated by sunlight and present in some foods and supplements, vitamin D has been associated with healthy bones and reducing the risk of diabetes and cancer. But a new study says that the recommended dose of vitamin D needed to reap these health benefits remains unclear. To help shed some […]

December 21, 2011
1
Cancer research , General interest
The War on Cancer, 40 years later

Friday, December 23, marks the 40th anniversary of President Richard Nixon’s declaration of a national “War on Cancer.” On that date in 1971, Nixon signed the National Cancer Act, which allocated $1.5 billion over three years for cancer research and control. He declared, “I hope that in the years ahead […]

December 20, 2011
0
Cancer research
Blood cancer research may lead to new treatments

At this year’s American Society of Hematology Annual Meeting, Dana-Farber scientists presented major findings that could one day improve diagnosis and treatment of blood cancers, extend life, or even cure some diseases. Among the highlights: Steven Treon, MD, PhD, and his colleagues identified a gene mutation that underlies the vast […]

December 13, 2011
0
Cancer research , Care for adults
Breast cancer specialist discusses treatment advances

Harold J. Burstein, MD, PhD, a Dana-Farber breast cancer specialist, discusses some of the important studies presented at the 2011 CTRC-AACR San Antonio Breast Cancer Symposium. The five-day meeting includes more than 1,000 scientific presentations, seminars, and posters, with a focus on emerging treatments in hard-to-treat populations, patients with metastatic […]

December 8, 2011
1

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