Cancer research , General interest
21st Century Cures Act Will Support ‘Revolutionary’ Cancer Research

On Dec. 13, President Barack Obama signed into law the 21st Century Cures Act, legislation that includes significant funding to the National Institutes of Health (NIH) to further the Beau Biden Cancer Moonshot, and to the Food and Drug Administration (FDA) to speed the drug approval process. Laurie Glimcher, MD, […]

December 14, 2016
0
Cancer research , Care for adults , Metastatic breast cancer , Treatments and Procedures
A New Approach to Understanding Breast Cancer Treatment Resistance

By Srivani Ravoori, PhD, American Association for Cancer Research This post first appeared on the Cancer Today website. In a study presented Dec. 7 at the San Antonio Breast Cancer Symposium, researchers conducted genomic analysis of estrogen receptor (ER)-positive metastatic breast cancer samples that had become resistant to therapies. They found […]

December 9, 2016
1
Breast cancer , Cancer research , General interest , Treatments and Procedures
What Is Adjuvant Therapy?

Adjuvant therapies are drug treatments that breast cancer patients receive after surgery to prevent cancer from returning. These treatments may include chemotherapy, anti-estrogen therapy, or anti-HER2 therapy. Watch More: Young and Strong Program Helps Young Women With Breast Cancer Life After Inflammatory Breast Cancer “This is now a widely established […]

December 2, 2016
0
Cancer research , Gastrointestinal Cancer , Immunotherapy , Pancreatic cancer
Can Immunotherapy Help Patients with Pancreatic Cancer?

Patients with pancreatic cancer often ask Dana-Farber’s Brian Wolpin, MD, MPH, about immunotherapy, the rising star of cancer treatment that’s making impressive gains against many types of malignancies. Immunotherapy drugs, which mobilize the patient’s immune defenses to recognize and attack tumor cells, have worked against lethal cancers such as melanoma […]

November 30, 2016
0
Cancer research , General interest , Neuroendocrine/Carcinoid tumors
What Are Carcinoid Tumors?

Carcinoid tumors are rare, often slow-growing tumors that form from neuroendocrine cells found throughout the body. Carcinoid tumors most commonly arise in the gastrointestinal system, including the appendix, small intestine, or rectum, but may occur in other sites, including the lungs. In most cases, there is no clear cause of […]

November 25, 2016
1
Cancer research , Health and Wellness , Health Topics , Lung cancers
How to Quit Smoking: What We Know

Smoking cigarettes contributes to 80 percent of lung cancer deaths in women and 90 percent of lung cancer deaths in men, and it is estimated to have caused more than 130,000 deaths from the disease between 2005 and 2010. But smoking damage does not stop with lung cancer: the habit […]

November 17, 2016
0
Cancer research , Head and Neck Cancer , Immunotherapy
Use of Immunotherapeutic Expanded to Fifth Type of Cancer

This post originally appeared on Cancer Research Catalyst, the official blog of the American Association of Cancer Research. It was originally published Nov. 15, 2016. By Karen Honey, PhD On Thursday, the U.S. Food and Drug Administration (FDA) announced that it had approved expanding the use of the immunotherapeutic nivolumab […]

November 15, 2016
4
Cancer research , Research , Risk and Prevention
What Are Tumor Markers?

Blood tests for the presence of substances called tumor markers can be helpful in diagnosing cancer and assessing how well treatment is working. But such tests alone generally can’t tell for certain whether someone has cancer or not. That’s why they are used in conjunction with other methods, such as […]

October 27, 2016
0
Bladder cancer , Cancer research , Immunotherapy
Immunotherapy Beats Chemotherapy for Advanced Bladder Cancer Patients

The immunotherapy drug pembrolizumab (Keytruda) is the first therapy of any kind to improve survival in patients whose metastatic bladder cancer worsened after treatment with platinum-based chemotherapy. Keytruda proved so much better than chemotherapy in this “second-line” use that an international clinical trial was halted when the advantage became apparent. […]

October 21, 2016
0
Cancer research , Ovarian cancer , Treatments and Procedures
Drug Prolongs Remissions in Some Relapsed Ovarian Cancers

Ed. note: Niraparib (Zejula) was approved by the U.S. Food and Drug Administration (FDA) on March 28, 2017, as a maintenance therapy for women with ovarian, fallopian tube, or primary peritoneal cancer. This post was originally published on Oct. 21, 2016. For women with relapsed ovarian cancer that responds to platinum-based […]

0
Cancer research , General interest , Research
What Can Be Learned from Clinical Trials that Fail?

When a clinical trial shows that a new treatment is no better than the standard, it can be disappointing. But such outcomes yield valuable, potentially lifesaving information. Trials can “fail” if the experimental therapy doesn’t work better than current treatments. These “negative” outcomes are important for several reasons. They can […]

October 14, 2016
0
Breast cancer , Cancer research , Care for adults , Treatments and Procedures
What Are Aromatase Inhibitors?

Aromatase inhibitors are drugs given to patients with hormone-receptor-positive breast cancer (HR+). They target the aromatase enzyme, which helps produce female hormones such as estrogen. Estrogen drives the growth of many HR+ tumors, and these drugs help control estrogen production, says Harold Burstein, MD, PhD, a breast cancer specialist in […]

October 6, 2016
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Cancer Genetics , Cancer research
Genetics vs. Genomics: What’s the Difference?

Gene, genetics, genome, and genomics all are derived from a Greek word – gen – meaning birth or origin. Almost every aspect of health and disease is influenced in some way by the inherited information in cells, written in the chemical code of DNA and packaged in distinct units known […]

October 4, 2016
0
Cancer research , Ovarian cancer
Ovarian Cancer: State of the Science

By Ursula Matulonis, MD This is an exciting time for those of us engaged in research and patient care for ovarian cancer. As we’ve learned more about this cancer – its early formation, molecular machinery, and the body’s defenses against it – we’ve also come to understand its weaknesses. An […]

September 29, 2016
0
Cancer research , Immunotherapy , Research
What’s New in Cancer Immunotherapy?

Keeping up with progress in the field of cancer immunotherapy requires paying close attention. The number of approved drugs that help the body’s immune system fight cancer continues to grow, as does the list of different cancers in which immunotherapy is proving effective – in some cases yielding dramatically longer-lasting […]

September 27, 2016
1
Cancer research , Patient Stories, Adult
Taking Action: Why One Cancer Patient Walks

by John O’Hara One day, I was sitting in a Dana-Farber waiting room, and I looked around at all of the people waiting with me. They were someone’s mother, father, sister, brother, child, neighbor, or friend — people just like me. And they were all facing what I was facing, […]

September 23, 2016
0
Blood Cancer , Blood disorders , Cancer research , Research
The Genomics Behind Blood Cancers and Other Blood Disorders

Many of the secrets of why precancerous conditions sometimes become cancerous are hidden in cells’ genes. At Dana-Farber, researchers are collecting tissue samples to see if they can pry open those secrets and unlock new treatment options for certain types of blood cancers and other blood disorders. They’re also exploring […]

September 13, 2016
0
Cancer research , Esophageal cancer , Health and Wellness , Risk and Prevention
Do Hot Drinks Increase the Risk of Esophageal Cancer?

Based on a review of numerous scientific studies, the International Agency for Research in Cancer (IARC) recently concluded that routine consumption of “very hot” drinks probably raises the risk of esophageal cancer. The review, by a panel of 23 experts around the world, found that drinking beverages such as coffee […]

September 6, 2016
0
Cancer research , Care for adults , Patient Stories, Adult , Research
Precursor Blood Condition Patient Pays it Forward

When Lori Kauzlarich discovered that she had a precursor blood condition in August 2013, she sprang into action. “I was stunned,” she says. “But I decided to advocate for myself.” Precursor conditions are blood disorders that may evolve into cancers such as leukemia, Waldenström’s macroglobulinemia, and multiple myeloma. They are […]

September 2, 2016
0
Cancer research , Endometrial (Uterine) cancer
What is the Latest Research in Endometrial Cancer?

For endometrial cancer, as for virtually every form of cancer, advances in genomics are transforming the understanding and treatment of this disease, which arises in the lining of the uterus or womb. As part of the Profile research project at Dana-Farber, Brigham and Women’s Hospital, and Boston Children’s Hospital, investigators […]

August 30, 2016
0

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