While chemotherapy can kill cancer cells, certain chemotherapy drugs can also cause an uncomfortable and distressing condition that may produce numbness, tingling, and discomfort in the arms or legs. This condition, known as peripheral neuropathy (CIPN), can make it difficult for people to perform day-to-day activities. Although there is no sure prevention for CIPN, there are ways to control the pain and minimize its effects on quality of life, says Cindy Tofthagen, PhD, ARNP, an assistant professor of nursing at the University of South Florida and post-doctoral fellow at Dana-Farber and the University of Massachusetts.
By Stacey Carroll Watch Stacey Carroll describe how she got her strength back. In my mental dictionary, strength had to do with will power and physical ability, and I believed I was strong according to my definition. I’ve been in the US Army for 20 years, served as a Commander twice, had been to Iraq and seen the brutality of war, kick-boxed in competitions, and worked as an ICU nurse. Diagnosed with breast cancer during my tour in Iraq, I received my care at Dana-Farber/New Hampshire Oncology-Hematology. I never envisioned the type of strength I would need. My definition had …
A group of specialists at the National Cancer Institute recently issued a report calling for a redefinition of the word “cancer,” suggesting that it no longer be applied to certain premalignant and non-lethal conditions. Such a change, the panel wrote, may ease the fears of patients, making them less inclined to seek unnecessary and potentially harmful treatments. The findings reinforce earlier studies by physicians at Dana-Farbers’ Susan F. Smith Centers for Women’s Cancers and others. An example of this kind of condition is ductal carcinoma in situ (DCIS), in which cancerous cells are confined to the milk ducts of the breast. …
by Richard Saltus Living with cancer is a physical and emotional challenge, but people may also find it hampers their thought processes and memory. Often the deficits are temporary, but sometimes they persist or appear months or years later as delayed effects. Cognitive difficulties, says Clare Humphreys, PhD, a neuropsychologist at Brigham and Women’s Hospital, “are caused not just by the direct effect of cancer, but also the effects of treatment, as well as factors like pain, disrupted sleep, anxiety, and depression.”
There are many decisions parents face after testing for genetic cancer risk, including whether to tell their children and how to approach the conversation. If you decide to talk to your children about the test results, allow yourself some time to process the information; you want to be calm and clear when you talk with them. Remember that you know your children best and there are no set rules for talking to kids about genetic tests.
By Ursula Matulonis, MD After a long period of slow progress, new knowledge about the genetics of ovarian cancer is leading to the development and testing of new therapies. Researchers at the Susan F. Smith Center for Women’s Cancers will soon be launching several phase 3 clinical trials testing drugs known as PARP inhibitors for patients with platinum-sensitive recurrent ovarian cancer – tumors that initially responded to platinum-based chemotherapy agents but have shown evidence of regrowth at least six months after treatment. Phase 3 trials test drugs in large numbers of patients to evaluate the drugs’ effectiveness as well as …
When Angelina Jolie underwent a preventative double mastectomy earlier this year, this issue of cancer risk and genetics made front-page headlines. Jolie, who announced the operation in a New York Times op-ed, tested positive for the BRCA1 gene mutation and learned she had an 87 percent risk of developing breast cancer. Jolie’s announcement left many women wanting to know more: What is a gene mutation? Should I undergo genetic testing? What should I do if my tests are positive?
By Nancy Campbell, MS Cancer-related fatigue is one of the most common complaints among cancer patients and survivors. This type of weariness, which typically occurs during treatment or in the first year after, is particularly difficult because it can last for long periods of time and doesn’t go away after sleep or rest. A growing body of research shows that cancer patients who get regular exercise report feeling less tired. If you’re interested in starting an exercise routine to address fatigue, consider these tips:
By Maura Perkins I can’t pinpoint when I started to get ovarian cancer symptoms. It was all very subtle and gradual. I was a healthy person. I ran, biked swam, hiked, and went to the gym regularly. A slight pain in my left side, difficulty digesting food, feeling of fullness, and shortness of breath: those were the subtle constellation of symptoms that landed me in my primary care doctor’s office. At the age of 50, I felt like I was going downhill fast.
By Melanie Graham Patients undergo different types of scanning procedures to produce detailed images of potential cancer growth. Depending on the cancer, physicians may use MRI, mammography, CT, PET/CT or other technologies. While some of these procedures use only x-rays or radio waves to create images, a PET/CT scan uses a combination of traditional x-rays and computer imaging. A radioactive substance similar to glucose is given to the patient, and because cancer cells tend to use more glucose than normal cells, PET/CT scans can help detect the biological activity of those cancer cells.