Outsmart Your Genes: Understanding BRCA1/2 Cancer Risk

When Angelina Jolie underwent a preventative double mastectomy earlier this year, this issue of cancer risk and genetics made front-page headlines. Jolie, who announced the operation in a New York Times op-ed, tested positive for the BRCA1 gene mutation and learned she had an 87 percent risk of developing breast cancer. Jolie’s announcement left many women wanting to know more: What is a gene mutation? Should I undergo genetic testing? What should I do if my tests are positive?

Exercise Can Help Fight Cancer Fatigue

By Nancy Campbell, MS Cancer-related fatigue is one of the most common complaints among cancer patients and survivors. This type of weariness, which typically occurs during treatment or in the first year after, is particularly difficult because it can last for long periods of time and doesn’t go away after sleep or rest. A growing body of research shows that cancer patients who get regular exercise report feeling less tired. If you’re interested in starting an exercise routine to address fatigue, consider these tips:

Living with Stage IV Ovarian Cancer

By Maura Perkins I can’t pinpoint when I started to get ovarian cancer symptoms. It was all very subtle and gradual. I was a healthy person. I ran, biked swam, hiked, and went to the gym regularly. A slight pain in my left side, difficulty digesting food, feeling of fullness, and shortness of breath: those were the subtle constellation of symptoms that landed me in my primary care doctor’s office. At the age of 50, I felt like I was going downhill fast.

What Should I Expect for my PET/CT Scan?

By Melanie Graham Patients undergo different types of scanning procedures to produce detailed images of potential cancer growth. Depending on the cancer, physicians may use MRI, mammography, CT, PET/CT or other technologies. While some of these procedures use only x-rays or radio waves to create images, a PET/CT scan uses a combination of traditional x-rays and computer imaging. A radioactive substance similar to glucose is given to the patient, and because cancer cells tend to use more glucose than normal cells, PET/CT scans can help detect the biological activity of those cancer cells.

New Therapies Bring Progress Against Multiple Myeloma

By Christine Cleary  The 21st century has seen great strides in treatment for multiple myeloma, a cancer of the bone marrow once considered a death sentence. In fact, thanks to research by Dana-Farber scientists, this blood cancer that took the lives of Geraldine Ferraro and Leonard P. Zakim has become a chronic disease for many patients.

An Overview of Lymphoma Therapy

More than 70 years ago, two pharmacologists began looking at mustard gas as a possible treatment for lymphoma. The chemical, used during World War I, lowered blood counts and destroyed lymph nodes in soldiers who were exposed to the gas. Two decades after the war, a thoracic surgeon named Gustav Lindskog used nitrogen mustard to successfully treat a patient with non-Hodgkin’s lymphoma.

Revisiting Cancer Care in Rwanda: One Year Later

By Lori Buswell, RN I recently returned from a three-month rotation as a nurse fellow at a comprehensive cancer center at Butaro Hospital in Rwanda, a tiny African country known as the “land of a thousand hills.” The hospital, built and operated by the Ministry of Health and Partners In Health, is located in a rural, mountainous area where most residents are farmers. Because most homes do not have running water, people fill up 5-gallon jugs at the local water spigot.

Making Fertility Decisions Post-Diagnosis

Liz Moroney celebrated her 23rd birthday in an unusual place — at a fertility clinic. Liz, a recent college graduate, wanted to plan for having children before it was too late. Diagnosed with Hodgkin’s lymphoma in June 2010, she spent 4 months in chemotherapy treatment in New York. Afterward, she and her reproductive endocrinologist watched her fertility numbers dwindle over a year of visits. Her endocrinologist was skeptical of the effectiveness of fertility treatment; So, too, was Liz.