Jonathan Owens says he was fortunate to get a second chance at life. By spreading the word, he hopes others won’t need similar luck. Owens had the same primary care physician for nearly 20 years, and was diligent about keeping himself in shape, as he reached his 50th birthday. Like many of his similarly aged … Read more
Richter’s syndrome involves the rapid transformation of chronic lymphocytic leukemia (CLL) into a significantly more aggressive form of lymphoma, usually diffuse large B-cell lymphoma (DLBCL), but occasionally Hodgkin lymphoma (HL). It arises in 2-10% of all patients with CLL and can occur at any time in the course of the disease. The goal of treatment … Read more
Blood cancers (or hematologic cancers) are diseases that originate in blood-forming tissue such as the bone marrow or cells within in the immune system. There are three main types of blood cancers: Leukemia: cancer that originates in the body’s blood-forming tissues, such as the bone marrow. The disease causes large numbers of myeloid blood cells … Read more
As a multi-sport athlete growing up, Allison Rebello loved being part of a team. Today, living with metastatic breast cancer (MBC), she credits three teams for helping her stay active and optimistic in the face of an incurable but treatable disease. Rebello’s care team at Susan F. Smith Center for Women’s Cancers at Dana-Farber/Brigham and … Read more
One bout of cancer is enough to contend with, but since 2014 Mary Johnson has had to cope with four different cancers and related conditions. Despite these tests of her physical and emotional strength, Johnson is doing well today after treatment at Dana-Farber. “Coming to Dana-Farber gave me confidence because they supported me, and I … Read more
Vaccines play a vital role in helping to keep us safe. They work by introducing our bodies to a weakened or modified version of a particular virus (such as measles, mumps, etc.). This allows our immune system to produce antibodies — proteins used by the immune system to attack and destroy foreign substances — in … Read more
Immunotherapy for cancer is a form of treatment that uses the body’s immune system to combat the disease. Today, immunotherapy is being applied to a wide range of cancers, often in combination with other agents, and clinical trials are exploring ways of improving and expanding its effectiveness. A particularly promising form of immunotherapy, known as … Read more
It’s impossible not to notice the connection between Crista Cardillo and Kim Stegmaier, MD. The way they laugh and swap stories might make you think they grew up down the street from one another. But their friendship began differently than most: as patient and oncologist at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center. When Cardillo … Read more
The first thing you should know is that most neck lumps are not a sign of cancer. There are a host of more common causes of neck lumps, including infections, cysts, boils, and other common skin irritations. However, a neck lump can also be an early sign of several types of cancer, so if your … Read more
Mantle cell lymphoma is a rare, often aggressive form of non-Hodgkin lymphoma (NHL), a cancer that involves white blood cells known as lymphocytes, which help protect the body from disease. It is named for its origins in the mantle zone — a ring of cells within the lymph nodes where B cells (a type of … Read more
It was a decade that began with the electrifying results of a clinical trial for a revolutionary new cancer therapy and ended with a Nobel Prize in Medicine for very different cancer-related research. In between those dramatic bookends, the 2010s were packed with progress, with discoveries leading to the FDA’s 2017 approval of the first … Read more
While 80 to 90 percent of reported thyroid lumps are not cancerous, performing “neck checks” can help you become familiar with what your thyroid looks and feels like, so you can tell your health care professional if you notice any changes. How to feel for thyroid lumps Sit or stand up straight, and make sure … Read more
Medically reviewed by Martha Wadleigh, MD Leukemia arises from malfunctions in stem cells within the bone marrow that cause abnormal white blood cells to flood into the bloodstream. Leukemias are classified as either myelogenous (also called myeloid) or lymphocytic, depending on which types of white blood cells are affected. What is the difference between these types … Read more
Medically reviewed by Sarah Feldman, MD, MPH Human papillomavirus (HPV) is a virus that can cause abnormal tissue growth and other changes to cells. It can be spread through skin-to-skin contact during sexual activity, and it can be carried by all sexes. There are over 100 different types (or strains) of the virus, which are … Read more
Medically reviewed by Robert Haddad, MD Throat cancer is one of many cancers that affect the head and neck area, including the nasopharynx, the area of the throat behind the nose; the oropharynx, middle part of the throat; the hypopharynx, the bottom section of the throat; the oral cavity where the tongue sits; and the … Read more
Scalp cooling is a simple treatment developed to help prevent or reduce hair loss caused by chemotherapy. Chemotherapy works by targeting rapidly dividing cells, and hair is the second fastest dividing cell — which is why many chemotherapy drugs cause hair loss. Scalp cooling reduces the blood flow to the cells that produce hair and … Read more
For a seven week stretch in 2018, Steve Kiley began each day with an inspirational quote. It was all part of his morning routine: he’d wake up, get ready for the day, and pull a sticky note off of the giant calendar created by his wife, Becky. The calendar helped Kiley count down his seven … Read more
Medically reviewed by Sarah Nikiforow, MD, PhD; George Demetri, MD; and Caron Jacobson, MD Among the most powerful new cancer treatments being developed today are “living drugs,” which are made by genetically modifying a patient or normal donor’s immune cell. The genetic modification is designed to alter the cells so that, when returned to the … Read more
Medically reviewed by F. Stephen Hodi, MD Melanoma is a rare but aggressive form of skin cancer that originates in melanocytes, the cells that create pigment (melanin) to protect us from ultraviolet (UV) radiation. Melanoma is categorized into one of three subtypes, depending on its location: Cutaneous melanoma: Melanoma of the skin. Common affected areas … Read more
Immunotherapy refers to treatments that use the body’s immune system to combat diseases. Immuno-oncology focuses on efforts to use the immune system as a weapon against cancer. The immune system is a collection of organs, tissues, specialized cells, and substances that protect the body against infection and disease. While the immune system can often handle very small … Read more