What are the Main Types of Gynecologic Cancers?

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Close to 100,000 women are diagnosed with a gynecologic cancer in the United States each year. In recognition of Gynecologic Cancer Awareness Month, we’re taking a look at the main types of gynecologic cancers and their symptoms. Cervical cancer In cervical cancer, cancer cells form in the tissues of the cervix, the lower, narrow end of the uterus. More than 12,000 new cases are diagnosed in the U.S. each year. Unlike other gynecologic cancers, cervical cancer has a standard screening test, the Pap smear, during which a doctor takes a sample of cells from the cervix. Doctors may also test …

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How Robotics are Improving Treatment for Head and Neck Cancers

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Head and neck (oropharyngeal) cancer is the sixth most common cancer in the U.S., with nearly 40,000 new cases diagnosed each year. Though tobacco and alcohol use can raise the risk of developing the disease, exposure to the human papillomavirus (HPV) poses an even greater risk. People who have had an oral HPV infection have a 50 times greater risk of developing head and neck cancer versus the general population. Currently, nearly three quarters of head and neck tumors test positive for HPV. A growing number of these newly diagnosed cases are among men in their forties and fifties. Since the early …

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Woman Finds Inspiration for Jimmy Fund Walk While Traveling the Country

It all began as a way to celebrate being 65 and healthy. Barbara Sirvis had been getting herself into the best shape she had been in since retiring as a college president. She wanted to recognize her accomplishment by doing something big, something that she couldn’t have done before. After some convincing from her friend and veteran walker, Betty McEnaney, Sirvis had her challenge: the Boston Marathon® Jimmy Fund Walk presented by Hyundai. That was year one, and Sirvis is now training for year four. But she no longer does it for herself; she does it for the patients and …

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New Immunotherapy Drug for Melanoma Wins Approval

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The Food and Drug Administration has approved a new type of  immunotherapy drug that will provide a much-needed option for patients with advanced or inoperable melanoma who no longer respond to other drugs – including the immunotherapy agent ipilimumab (Yervoy). The drug, pembrolizumab or MK-3745, will be marketed under the name  Keytruda. Based on impressive performance in clinical trials, the FDA had designated pembrolizumab a “breakthrough therapy” and placed it on a fast-tracked approval process. “This drug is exciting because of its really striking response rate and good indications that these responses are durable” for a least a year, says Patrick Ott, MD, PhD, clinical …

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Dentist Brings a Smile to Transplant Patients

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Like many family members of cancer patients, Stephen Matarazzo, DMD, wanted a meaningful way to thank the Dana-Farber caregivers who saved his son Michael’s life. What he came up with involved offering his own professional expertise to protect the smiles of others. A dentist based in Quincy, Mass., Matarazzo provides pro bono dental exams and services to cancer and benign hematology patients who, like his son did, need stem cell transplants. Dental visits are critical transplants suppress the immune system, and patients are at significant risk for developing infections – in some cases life-threatening ones. The oral cavity and teeth …

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Understanding the New Treatment Guidelines for HER2-Negative Breast Cancer

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A new national guideline for the treatment of women with a type of advanced breast cancer known as HER2-negative disease balances state-of-the-art evidence with a need to tailor therapy to each patient’s circumstances and preferences. The guideline, developed by a panel of experts convened by the American Society of Clinical Oncology (ASCO), will help clarify the choices facing patients and physicians in treating one of the most common forms of breast cancer. Nearly 80 percent of advanced breast cancers are classified as HER2-negative, meaning the cancer cells do not have excess amounts of the HER2 protein and don’t respond to …

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Adult Leukemia: Five Things You Need to Know

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More than 52,000 new cases of adult leukemia are diagnosed in the U.S. each year. Although it is one of the more common childhood cancers, leukemia is found more often in older adults. As September marks Leukemia and Lymphoma Awareness Month, we look at some important facts about adult leukemia: 1.     What are the different types of leukemia? Leukemia is a cancer of the blood. Main types of leukemia include: Acute Myeloid Leukemia (AML) – AML causes the bone marrow to produce immature white blood cells (called myeloblasts). As a result, patients may have a very high or low white …

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New Surgery Technique Expands Treatment Options for Brain Tumor Patients

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For many patients with brain tumors or other abnormal tissue located deep in the brain, treatment options have been limited. Last year, Jill Colter, now 50, discovered that a brain tumor resulting from Stage IV melanoma had returned. “Several years earlier, I had treatment with surgery and radiation, but the tumor came back,” Jill said. Due to the location of Jill’s tumor and her prior radiation, surgery and further radiation weren’t possible to treat her tumor. Colter was referred to neurosurgeon Alexandra Golby, MD, director of image-guided neurosurgery and clinical co-director of the Advanced Multimodality Image Guided Operating (AMIGO) Suite …

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Months After Transplant, Teen Hits the Soccer Field

Some 100 days after receiving a stem cell transplant to cure his severe aplastic anemia, 13-year-old Behaylu Barry still couldn’t invite friends into his home. He can’t return to school until January, when his immune system will finally be strong enough to fight the pathogens present in indoor spaces. Yet  Behaylu was doing so well that he was cleared to play soccer – outdoors, of course — for the first time since February, when he was diagnosed with the life-threatening blood disorder. On August 23, Behaylu walked onto the field with the Exeter (N.H.) Hawks for a two-game pre-season tournament. …

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Get the Facts on Metastatic Breast Cancer

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When breast cancer spreads to other parts of the body it is known as metastatic breast cancer (MBC), or metastatic disease. MBC is also sometimes referred to as advanced stage breast cancer or stage IV breast cancer. Although there is no cure for MBC, it is treatable. Thanks to new treatments developed through clinical trials, women with MBC are often able to lead full, active lifestyles with a good quality of life. We sat down with Rachel Freedman, MD, MPH, a breast oncologist with the Susan F. Smith Center for Women’s Cancers at Dana-Farber, to learn more:   Are there …

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