Cancers of the cervix are diagnosed in more than 12,000 women in the United States every year. Worldwide, the annual tally of new cases reaches more than half a million. The biggest advance against the disease in recent years has come in the area of prevention. Vaccination against the human papilloma virus (HPV) – two … Read more
In its Annual Report to the Nation on the Status of Cancer, the National Cancer Institute reported that between 2002-2011, colorectal cancer and lung cancer rates dropped among men and women in the United States. Despite these gains, statistics showed higher rates of both thyroid cancer and liver cancer. The increases for these diseases could … Read more
When Roy Jann was diagnosed with cancer in 2013, it never crossed his mind that he would be a model for the life-saving potential of venetoclax, a new type of cancer drug that had recently entered human testing. The first inkling that something was amiss had come a few weeks earlier, while Jann was biking … Read more
This post originally appeared on WBUR’s CommonHealth blog. By Barrett Rollins, MD, PhD President Obama’s call for a new national effort against cancer – a “moon shot” – comes at a most opportune time. Cancer research has advanced significantly and now genomic analysis of individuals’ tumors can reveal the specific DNA changes that drive cancer … Read more
By Edward J. Benz, Jr., MD, president and CEO, Dana-Farber Cancer Institute Yesterday, the Boston Board of Health approved a policy raising the minimum age for buying tobacco from 18 to 21. This is great news. As a former smoker, I know how easy it was to pick up the habit at age 18. I … Read more
In recent years, studies have shown that foods like coffee and nuts may be able to lower risk of colon cancer. Aspirin, too, has been linked to reducing risk. Despite these studies, experts still stand by screening as the number one way to prevent the disease. “There are many different ways we can prevent this … Read more
This blog post originally appeared on Cancer Research Catalyst, the official blog of the American Association for Cancer Research. By Karen Honey, PhD Last week, new ground was broken in the field of cancer immunotherapy when the U.S. Food and Drug Administration (FDA) approved the first cancer treatment to combine two of these cutting-edge agents: … Read more
The past two years have seen a surge of new treatments for blood cancers, such as lymphoma, leukemia and multiple myeloma. Research on the genetic flaws underlying specific cancer types has led to new precision drugs such as ibrutinib and idelalisib and new immunotherapy agents that are improving outcomes in many patients with difficult-to-treat forms … Read more
This post originally appeared on the AACR Cancer Research Catalyst Blog. This week, the American Association for Cancer Research (AACR) released the results of a national survey on American voters’ opinions about cancer and cancer research funding in conjunction with its fifth annual Cancer Progress Report. The report highlights how federally funded research can power … Read more
The inner world of a cancerous tumor is a place of intense rivalry, subversion, and aggression. Multiple subgroups of malignant cells – each with its own pattern of molecular features – vie with one another for nutrients, access to the blood supply, and room to grow and spread. This diversity, or “heterogeneity,” complicates efforts to … Read more
The Food and Drug Administration’s approval of the drug Iressa® for a form of metastatic lung cancer represents a return to prominence for the compound that launched the era of targeted therapy in lung cancer – even if that wasn’t clear at the time of its original clinical trial in patients. The FDA approved Iressa (gefitinib) … Read more
Any treatment that uses elements of the body’s immune system to fight cancer is considered cancer immunotherapy. In recent years, as research has revealed many of the basic workings of the immune system and how the immune system interacts with tumor cells, scientists have developed, tested, and demonstrated the effectiveness of an array of immunotherapy … Read more
Updated Oct. 28, 2015 Almost as long as scientists have known of the existence of viruses, they’ve dreamed of using the tiny pathogens as a weapon against cancer. Now, as a result of advances in genetic engineering and insights into the workings of the immune system, science is giving substance to the dream. A variety … Read more
The growing excitement about the potential of immunotherapy treatments for cancer continued at the 2015 meeting of the American Association for Cancer Research (AACR), one of the largest cancer research meetings of the year. Several Dana-Farber investigators presented encouraging results of immunotherapy for melanoma, lung cancer, and breast cancer. F. Stephen Hodi, MD, and Leena … Read more
By John Quackenbush, PhD Everyone at Dana-Farber knows me as a scientist. Maybe a little crazy, but dedicated to cracking the code that drives cancer. And everyone who has spent time with me knows that I can talk (seemingly endlessly) about my work. But today I am going to share a different story about an … Read more
When Elizabeth Cahn was presented with her treatment options for triple-negative breast cancer, the decision was about more than just getting healthy; it was about “paying it forward.” “I know there are many people who participated in clinical trials before I came along and it was because of their participation that researchers were able to … Read more
In two recent books and the Ken Burns TV documentary, “Cancer: The Emperor of All Maladies”, prominent researchers explain eloquently why cancer is such a stubborn problem and detail how the latest treatment strategies are gaining ground – if slowly. “There have been so many wonderful changes,” says David G. Nathan, MD, president emeritus of … Read more
In a country as geographically vast as the United States, and with a large and mobile population, it’s not surprising that cancer rates vary by region, by state, and even by localities within states. Geographical differences exist in overall cancer rates and in specific types of cancer, according to 2019 data published by the U.S. Centers for … Read more
Although malignant melanoma has been attracting much of the media spotlight because of promising new immunotherapy drugs, advances are also being made in other types of skin cancer. Nonmelanoma skin cancers, such as basal cell carcinoma and squamous cell carcinoma, are very common, with more than 3.5 million cases diagnosed annually. In fact, it’s estimated … Read more
The information used in diagnosing a brain tumor takes many forms. At Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC), patients’ brain tumor tissue undergoes a broad range of diagnostic tests: not only standard pathology exams in which tumor cells are viewed under a microscope, but also next-generation scans for mutated genes and misassembled chromosomes, as well … Read more