Actress Angelina Jolie is no stranger to the headlines, but she stunned the world with her Op-Ed in The New York Times, in which she shared her very private decision to have a preventive double mastectomy after testing positive for the BRCA1 gene mutation. “I hope that other women can benefit from my experience,” wrote Jolie. “Cancer is still a word that strikes fear into people’s hearts, producing a deep sense of powerlessness.” But for Jolie, and many others, getting genetic testing and taking action may offer control and comfort.
We know that women who inherit harmful mutations in the genes BRCA1 or BRCA2 have a sharply increased risk of developing breast and/or ovarian cancer at an early age (prior to menopause). In fact, women with inherited BRCA1 or 2 mutations are about five times more likely to develop breast cancer – and at least 10 times more likely to develop ovarian cancer – than women without such mutations, according to the National Cancer Institute. Read more
Win or lose, Miss America contestant Allyn Rose made news with her decision to undergo a double mastectomy. According to the Associated Press, Rose, who lost her mother to breast cancer, inherited a rare genetic mutation which might put her at greater risk for developing cancer.
Her decision to have the preventive surgery has sparked questions about genetics, cancer risk and strategies for preventing cancer.
As we approach the Thanksgiving meal, Dana-Farber nutritionists offer some easy tips for enjoying the holiday without packing on pounds.
The average Thanksgiving dinner contains at least 3,000 calories. When you add in snacks, appetizers, and drinks throughout the day, you may end up consuming approximately 4,500 calories (two to three times what you may normally eat). Although this is only one meal, excess calories from a holiday season are unhealthy in the long run, as obesity is a risk factor for cancer. Read more
People often ask me: How do you manage to live with metastatic breast cancer? One of the most important strategies for me has been building a support network.
My diagnosis of breast cancer that had already spread to my bones came out of the blue. I had a normal mammogram 13 months earlier, and no known risk factors. So when I heard the news in August 2008, my first impulse was to reach out for support. Read more
In 2012, it is estimated that more than 22,000 new cases of ovarian cancer will be found, and over 15,000 women will die from the disease, according to the National Cancer Institute. Unfortunately, in many cases the cancer isn’t detected until it is advanced. It’s important to recognize the symptoms and urge the women in your life to take early action.
Genes don’t cause cancer, but genetic mutations can. Our cells have about 22,000 genes, which consist of DNA packed into chromosomes inside the cell nucleus. These genes control a wide range of functions, including cell growth and division. When the genes misbehave or mutate, cancer can develop. Read more
For many women who enjoy a glass of wine, research showing that relatively small amounts of alcohol can raise their risk of breast cancer are disconcerting, to say the least. And confusing, too.
How much drinking is OK? Isn’t a glass of red wine a day good for your heart — and couldn’t that be more important?
In the past five or 10 years, knowledge about alcohol and breast cancer has been changing as studies produce new results and are publicized, sometimes over-dramatically, in the media. At the same time, there’s growing evidence that moderate drinking can be healthy for the heart. Read more