Cancer research , Care for children
In Precision Medicine, Pioneering Young Patient Teaches Veteran Doctor

Allison Schablein seems an unlikely candidate to teach medicine to Mark Kieran. She’s an 8–year-old New Hampshire second grader who loves basketball, hip hop, acrobatic dancing and jewelry. He’s a pediatric neuro-oncologist with a PhD in molecular biology, not to mention decades of clinical and research experience. But teach Kieran, […]

January 28, 2016
0
Care for adults
Can Cancer Patients Participate in More Than One Clinical Trial at a Time?

Clinical trials are a key part of medical science’s effort to improve treatments for cancer patients. There are a variety of different types of trials, including therapeutic clinical trials, which test the safety and effectiveness of potential new agents in patients. Some patients participate in several therapeutic clinical trials, in […]

December 22, 2015
0
Uncategorized
Scientific ‘Salvage’ Project Advances Understanding of AML

It looked like a scientific dead end – a clinical trial that found no benefit to a potential drug for a form of leukemia. But, like police detectives working a cold case, Dana-Farber scientists gathered hundreds of tissue samples that had been collected for the study – most of them […]

April 2, 2015
0
Cancer research , Care for adults
What Is It Like to Enroll in a Clinical Trial?

When Elizabeth Cahn was presented with her treatment options for triple-negative breast cancer, the decision was about more than just getting healthy; it was about “paying it forward.” “I know there are many people who participated in clinical trials before I came along and it was because of their participation […]

March 31, 2015
1
Cancer research , Care for adults
Five Common Myths About Clinical Trials

Better cancer treatments depend on clinical trials of new drugs and other therapies, but in the United States, only 3 percent of cancer patients participate in these investigations of new therapies. Patients often hesitate to participate because they don’t understand the process or have misconceptions about what it means for […]

March 9, 2015
2
Care for adults
What is Liposarcoma?

Cancers known as sarcomas develop in the connective tissues, such as muscle, fat, and bone, that hold the body together. The type of sarcoma diagnosed in Toronto Mayor Rob Ford, liposarcoma, originates in fat cells that have been driven by random DNA errors into malignant growth, forming tumors. George Demetri, […]

September 19, 2014
0
Cancer research
How is Research Improving Treatment of Head and Neck Cancers?

Head and neck cancers account for 3 to 5 percent of all cancers in the United States and can occur in the oral and nasal cavities, the sinuses, the throat, the larynx, the salivary glands, and the thyroid. When diagnosed early, many head and neck cancers can be cured with […]

August 25, 2014
0
Cancer research
Research Advances Hold Promise for Multiple Myeloma Treatment

Multiple myeloma is one of the most compelling examples of a cancer in which research has markedly improved the length and quality of patients’ lives in the last decade. A malignancy of certain white blood cells in the bone marrow known as plasma cells, myeloma is still considered incurable, but treatment […]

July 28, 2014
1
Cancer research
What is a Phase I Clinical Trial?

Nearly all cancer drugs in use today were developed through clinical trials. But before they are approved for use, they must go through multiple phases designed to test the drug’s safety and efficacy. These phases include preclinical, phase I, II, and III. In phase I clinical trials, investigators evaluate how […]

June 6, 2014
2
Cancer research
Webchat: The Latest in Breast Cancer Treatment and Research

With new approaches to therapy and increased understanding of the biology of cancer, breast cancer treatment has made significant progress in recent years. “I am personally very excited about what’s to come for breast cancer treatment,” says Eric Winer, MD, director of the Breast Oncology Program in the Susan F. […]

June 2, 2014
3
Cancer research
Precision Medicine for Lung Cancer Marks Tenth Anniversary

Ten years ago researchers at Dana-Farber and in Japan published a study showing that lung cancer patients whose tumors had a malfunctioning version of a protein called Epidermal Growth Factor Receptor (EGFR) responded dramatically to a drug that specifically targets the EGFR protein. The findings launched the era of precision […]

April 30, 2014
0
Cancer research , Care for adults
New Experimental Breast Cancer Drug Shows Promise

Reports of an experimental drug that slowed advanced breast cancer in a clinical trial have stirred excitement at a national research meeting and breathed new life into a cancer-fighting strategy that had seemed to falter. In one study, the drug, palbociclib, doubled the length of time without disease progression in […]

April 18, 2014
0
Cancer research , Care for adults
Young Woman with Breast Cancer Finds Dream Team

A young woman in her prime, with a full life and meaningful career, does not expect a cancer diagnosis. But that is what happened to 34-year-old Erin, who received the news when she was in Paris with her mother and sister, on a long-awaited trip to celebrate Mother’s Day.

April 3, 2014
0
Cancer research , Care for adults
New Treatment Option for Chronic Lymphocytic Leukemia

The Food and Drug Administration’s recent approval of the drug ibrutinib offers a major new option for patients with chronic lymphocytic leukemia (CLL) who tried at least one prior therapy, physicians say.

March 26, 2014
0
Cancer research
Clinical Trials Paving the Way for Improved Vulvar Cancer Treatment

Cancers of the vulva – the external portion of the female genitals – are diagnosed in approximately 4,700 women in the United States each year. While many patients can be cured by a combination of surgery, chemotherapy, and radiation therapy, others – particularly those whose cancer has metastasized to other […]

March 18, 2014
3
Cancer research , General interest , Health and wellness
DNA Test May Offer Alternative to Pap Smear

A Food and Drug Administration (FDA) panel has recommended that a DNA test should be the primary screening tool for cervical cancer, rather than the traditional Pap smear. The DNA test detects the DNA of human papillomavirus (HPV), the sexually transmitted infection that causes almost all cases of cervical cancer. […]

March 17, 2014
3
Cancer research
A History of Multiple Myeloma Advances

Not long ago, a diagnosis of multiple myeloma — a cancer of the bone marrow — carried with it a very poor prognosis, with median survival estimates of just two to three years. Now, thanks in large part to research and treatment advances at Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC), […]

February 24, 2014
7
Cancer research
Progress and Promise in Prostate Cancer Research

In prostate cancer – the most common cancer in men aside from skin cancer – scientists are working to answer some of the most basic questions about the disease while developing an array of new treatments. Using the prostate-specific antigen (PSA) blood test, doctors are often able to detect prostate […]

February 17, 2014
1
Cancer research , Care for adults
Brokaw Diagnosis: What is Multiple Myeloma?

NBC News’ Tom Brokaw, 74, revealed this week he has multiple myeloma, a cancer of the bone marrow. The disease, also known as plasma cell myeloma, will be diagnosed in more than 24,000 Americans this year.

February 12, 2014
3
Cancer research , General interest
Is Cancer More Serious If You Also Have Another Disease?

When cancer develops in someone with other diseases, it can be more serious, according to a recent annual report from several national cancer organizations. “Cancer does not occur in isolation,” says Lawrence Shulman, MD, in commenting on the report. “It occurs in a human being, who may have other medical problems.”

January 27, 2014
1
Cancer research
New Research Shows Progress in Breast Cancer Treatment

The 36th annual San Antonio Breast Cancer Symposium, which ran from Dec. 10-14, brought news of significant advances against a disease that strikes more than 230,000 women and 2,000 men in the United States each year. The more than 1,000 research papers presented by thousands of scientists and physicians ranged […]

December 16, 2013
0
Cancer research
Research Report: New Treatments for Melanoma

by Richard Saltus As recently as five years ago, progress in treating life-threatening malignant melanoma was slow. Since then, several molecularly targeted drugs have burst on the scene, and new strategies for awakening the immune system to attack the cancer cells have yielded dramatic long-term survival benefits for some patients. […]

November 18, 2013
5
Cancer research , General interest , Health and wellness
Infographic: Pancreatic Cancer by the Numbers

As November marks Pancreatic Cancer Awareness Month, view the infographic below to learn more about the disease:

November 15, 2013
0
Cancer research , Care for adults
Clinical Trials and the Future of Lymphoma Treatment

Current lymphoma therapies are a far cry from the mustard gas used more than 50 years ago. More treatment options, including ones that may be more effective and less toxic, are being studied in ongoing clinical trials. “Clinical trials really are the future of lymphoma treatment,” says Ann LaCasce, MD, […]

November 14, 2013
1
Cancer research , Care for adults
Targeting Triple-Negative Breast Cancer

Breast cancer may develop in one part of the body, but it’s not just one disease. In fact, oncologists think of breast cancer as at least three different types of diseases. Triple-negative breast cancer (TNBC) describes breast cancer cells that do not have estrogen, progesterone, or HER2 receptors. It makes […]

October 7, 2013
0
Cancer research , Care for adults
Research in Advanced Ovarian Cancer Shows Promise

By Ursula Matulonis, MD After a long period of slow progress, new knowledge about the genetics of ovarian cancer is leading to the development and testing of new therapies. Researchers at the Susan F. Smith Center for Women’s Cancers will soon be launching several phase 3 clinical trials testing drugs […]

August 2, 2013
1
Cancer research , Care for adults
Living with Stage IV Ovarian Cancer

By Maura Perkins I can’t pinpoint when I started to get ovarian cancer symptoms. It was all very subtle and gradual. I was a healthy person. I ran, biked swam, hiked, and went to the gym regularly. A slight pain in my left side, difficulty digesting food, feeling of fullness, […]

July 24, 2013
11
Care for adults
New Therapies Bring Progress Against Multiple Myeloma

By Christine Cleary  The 21st century has seen great strides in treatment for multiple myeloma, a cancer of the bone marrow once considered a death sentence. In fact, thanks to research by Dana-Farber scientists, this blood cancer that took the lives of Geraldine Ferraro and Leonard P. Zakim has become […]

July 18, 2013
21
Cancer research
Clinical Trials for Cancer Patients

By Ian Krop, MD, PhD Clinical trials are scientific studies in which new treatments – drugs, diagnostic procedures, and other therapies – are tested in people to find out if they are safe and effective. Nearly all cancer drugs in use today were tested in clinical trials.

June 10, 2013
4
General interest , Health and wellness
A User’s Guide to Cancer-Related News

By Vish Viswanath, PhD News about advances in cancer research and treatment appears almost daily. The pace at which new findings are reported, coupled with the complexity of the underlying science, can make it difficult to know which studies are truly significant and which are less so. It’s easy to […]

June 3, 2013
0
Cancer research
Why We Need to Fund Cancer Research

One of the goals of the Rally for Medical Research, held in conjunction with the American Association for Cancer Research (AACR) 2013 Annual Meeting, earlier this month was to bring awareness to and education about the impact of the cuts in federal funding for medical research. Dana-Farber’s Kenneth C. Anderson, MD participated in the Rally. […]

April 18, 2013
1
Cancer research
Rally to Support Cancer Research Today

by Robert Levy More than 18,000 cancer scientists from around the world are in Washington, D.C., this week for the annual meeting of the American Association for Cancer Research (AACR). The meeting serves as a forum for the presentation and discussion of the latest discoveries in cancer research. The meeting […]

April 8, 2013
0
Cancer research
Zeroing In On Dark Matter

By Richard Saltus If the human genome – the complete set of  DNA blueprints in a cell for building a human being — is truly “the book of life, ”  as it has been called, then 99 percent of life’s book is gobbledygook. Only 1 percent of the DNA contains […]

March 8, 2013
0
Cancer research
Sequestration Could Slow the Pace of Biomedical Research

By Edward J. Benz, Jr., MD The automatic budget cuts (or sequestration) that went into to effect as a result of the Budget Control Act of 2011, could have a chilling long-term effect on scientific research in the United States. The automatic cuts will slash 5.1 percent – or about […]

March 4, 2013
1
Care for adults
Getting a Second Opinion About Your Cancer Care

Most people seek opinions from experts when it comes to important matters, such as finances, children’s education, or a major purchase. Why not do so when it comes to your cancer treatment?

February 12, 2013
8
Cancer research , Care for adults
Can Breast Cancer Patients Avoid Multiple Surgeries?

When Jane Davis was diagnosed with breast cancer last July, she began learning as much as she could about her disease. Davis quickly discovered one of the most startling statistics about breast cancer: Up to 40 percent of women who have a lumpectomy require a second surgery. That’s because surgeons often […]

January 2, 2013
4
Care for children
Treating Eye Cancer Directly

For years, researchers have sought an avenue to deliver chemotherapy directly to retinoblastoma tumors – cancers of the retina of the eye, which primarily affect children under age 5. It turns out that the body itself offers just such a route.

September 18, 2012
0
Care for adults
Symptoms of Ovarian Cancer – Margaret Winchester’s Story

September is Ovarian Cancer Awareness Month and in recognition of that, we asked ovarian cancer survivor Margaret Winchester to share her story. After being diagnosed with advanced (stage IIIC) ovarian cancer in 2008, I chose Dana-Farber for my care because I knew about the Institute’s cutting-edge approach to cancer care […]

September 13, 2012
0
Cancer research , Care for adults
Doctor/patient team fight rare cancer

By Karen Lee Sobol I recently learned that the word “patient” shares a Latin root with the word “compassion.” Any one of us can become a patient, for a number of reasons. For me, hearing a diagnosis of Waldenström’s macroglobulinemia flipped a switch. I became a patient in a big way.

August 2, 2012
4
Cancer research
What is immunotherapy for cancer?

Immunotherapy is one of the most technologically advanced yet basic forms of cancer treatment. It uses the body’s own defense mechanism, the immune system, to fight cancer. Immunotherapy is probably most familiar to you in the form of vaccinations for the flu, polio, chicken pox, and other contagious diseases. In […]

June 5, 2012
0
Care for children
A new approach to old ideas about diffuse intrinsic pontine glioma

Hilary Olson had no reason to suspect that her daughter Hailey might have a brain tumor. “Her smile was starting to droop a little, and one of her eyes was a little jumpy,” says the 6-year-old’s mother. “We took her to see a neurologist, and he thought she might have […]

May 30, 2012
10
Care for adults
New developments in brain tumor treatment: Five questions for David Reardon, MD

More than 600,000 people in the United States are living with a primary brain tumor — one that begins and stays in the brain — and over 60,000 adults and children will be diagnosed with a brain tumor this year. In recognition of May as Brain Tumor Awareness Month, we […]

May 22, 2012
2
Cancer research , Care for adults
A Life Saved by Second Opinions, Experimental Treatments, and a Touch of Luck

By James Bond “How long will I live?” I asked my oncologist in Ohio in 1992, when I was 44 and diagnosed with multiple myeloma. “Three years,” he answered. Instead, I enjoyed 10 more years of active living. Then my disease began to overtake me; my kidneys were failing, I […]

May 3, 2012
13
Cancer research
From old drugs, new cancer treatments

When it comes to finding better drugs for cancer, Dana-Farber oncologist Dr. David Frank is not a patient man. While new cancer science promises to bring novel, improved therapies to the bedside, it can take many years — and Frank isn’t willing to wait. “We need to get new treatments […]

March 1, 2012
0
Cancer research , Care for adults , Health and wellness
The benefits of vitamin D

Activated by sunlight and present in some foods and supplements, vitamin D has been associated with healthy bones and reducing the risk of diabetes and cancer. But a new study says that the recommended dose of vitamin D needed to reap these health benefits remains unclear. To help shed some […]

December 21, 2011
1
Cancer research
Blood cancer research may lead to new treatments

At this year’s American Society of Hematology Annual Meeting, Dana-Farber scientists presented major findings that could one day improve diagnosis and treatment of blood cancers, extend life, or even cure some diseases. Among the highlights: Steven Treon, MD, PhD, and his colleagues identified a gene mutation that underlies the vast […]

December 13, 2011
0

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