The Food and Drug Administration’s recent approval of the drug ibrutinib offers a major new option for patients with chronic lymphocytic leukemia (CLL) who tried at least one prior therapy, physicians say.
Tag Archive for CLL
By Buck Rogers
When I woke up from a 40-minute operation to remove a lymph node from my neck, my Ear, Nose & Throat surgeon approached me with another doctor and said, “I’d like you to meet your oncologist.” My life instantly changed; I was diagnosed with chronic lymphocytic leukemia.
After about six weeks of being scared, wondering how much time was left, trying to figure out what to tell our kids and our parents, my wife and I decided that the only choice was to fight as hard as we could. I started by running up and down Village Street in Medway, Mass., barely getting a mile before feeling winded. But the thought of doing nothing was even more frightening, so I kept running.
When it comes to finding better drugs for cancer, Dana-Farber oncologist Dr. David Frank is not a patient man. While new cancer science promises to bring novel, improved therapies to the bedside, it can take many years — and Frank isn’t willing to wait.
“We need to get new treatments to patients as soon as possible,” he says. Read more
At this year’s American Society of Hematology Annual Meeting, Dana-Farber scientists presented major findings that could one day improve diagnosis and treatment of blood cancers, extend life, or even cure some diseases.
Among the highlights:
Steven Treon, MD, PhD, and his colleagues identified a gene mutation that underlies the vast majority of cases of Waldenström’s macroglobulinemia, a rare form of non-Hodgkin lymphoma. The results suggest that new, effective treatments are now possible for people with Waldenström’s. Read more about Dr. Treon’s Waldenström’s macroglobulinemia research breakthrough.
Catherine J. Wu, MD, co-led investigators who discovered nine new gene mutations that could help doctors predict if and how chronic lymphocytic leukemia (CLL) will progress, and lead to new treatments for CLL. Take a closer look at Dr. Wu’s CLL research.
Corey Cutler, MD, MPH, and his colleagues reported on a new clinical trial that may improve the ability of stem cells from umbilical cord blood to take root in patients receiving a stem cell transplant more quickly and with a higher degree of success. Learn more about Dr. Cutler’s stem cell transplant clinical trial.