By Tom Ulrich
One of the hot trends in drug discovery could be called drug re-discovery: finding new uses for drugs that have already received FDA approval for a different indication.
It’s an approach that allows researchers and clinicians to rapidly test potential treatments for rare or difficult-to-treat conditions. Because the drug’s safety profile is already known, much of the preclinical and early clinical work that goes into developing a drug can be bypassed.
By Buck Rogers
When I woke up from a 40-minute operation to remove a lymph node from my neck, my Ear, Nose & Throat surgeon approached me with another doctor and said, “I’d like you to meet your oncologist.” My life instantly changed; I was diagnosed with chronic lymphocytic leukemia.
After about six weeks of being scared, wondering how much time was left, trying to figure out what to tell our kids and our parents, my wife and I decided that the only choice was to fight as hard as we could. I started by running up and down Village Street in Medway, Mass., barely getting a mile before feeling winded. But the thought of doing nothing was even more frightening, so I kept running.
By Julia Pettengill
Our daughter Sophie was diagnosed with leukemia at age 2½, and received two years of care at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center. While I felt tremendous joy and relief when she completed treatment, I also found the experience traumatic. Read more
Stem cell transplantation (sometimes called bone marrow transplants) is a treatment for certain forms of cancer, such as leukemia, lymphoma, and multiple myeloma, as well as other diseases. But before a patient can receive a transplant, stem cells must be collected from a donor (an allogeneic donation) or from the patient (an autologous transplant). Read more
By Tim Crowley
This Veteran’s Day, Dana-Farber thanks our patients, survivors, families, and friends who have served or are serving in the armed forces, including survivors Stacey Carroll, Ben Groen, and Tim Crowley, who tells his story below.
In June 2010, I was diagnosed with acute myeloid leukemia (AML), a fast-moving disease where too many immature white blood cells are present in the blood and bone marrow, after doctors found abnormalities in routine blood work for the Marines. My wife, Julie, and I were in shock. We had just celebrated Father’s Day with our two young children, Jack and Kate, and now we would be spending the foreseeable future at Dana-Farber/Brigham and Women’s Cancer Center.
Cancer or blood disorder patients may have central lines, which make it easier to receive certain medications (such as chemotherapy) and have blood tests. The major types of central lines include Port-A-Cath, Hickman, and peripherally inserted central catheter (PICC). Patients receiving stem cell transplants sometimes have central lines.
If you have a central line, you may need to care for it at home. Or you may need guidance in caring for a loved one with a central line. Knowing the correct procedures is essential to preventing infection. Read more
by Martha Laperle
When my son Ryan ran the Boston Marathon this year, I watched him with a special level of pride. Not only had he completed his first-ever marathon in four hours, but he was running, in large part, because of me.
Just over a year earlier, at the age of 57, I had been diagnosed with an aggressive form of acute myeloid leukemia (AML), a diagnosis that turned my life upside down and led to weeks of chemotherapy and a stem cell transplant at Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC). Ryan was running to raise funds for the Leukemia & Lymphoma Society and had received nearly $11,000 in pledges.
Barely a minute after Ryan crossed the finish line, the area shook with explosions. Read more
By Stephen Sallan, MD
Today, three quarters or more of all childhood cancer patients will be cured of their disease, a higher percentage than ever before. And the numbers will only get better as we learn more about the biology of childhood cancers and develop new ways of treating them.
Just as Dana-Farber tailors treatment and support to children and young adults, the Older Adult Leukemia Program ̶ a specialized, clinical service ̶ addresses the other end of the spectrum: adults who are 65 and older, and have blood cancer such as leukemia or other bone marrow disorders. Read more
by Naomi Funkhouser
April 2011 was an auspicious month for Hilary Hall. The start of spring marked 15 years of her being cancer-free, as well as the anniversary of her bone marrow transplant in April 1996 at age 12 for acute myelogenous leukemia. It also marked the first time Hall would lace up her running shoes for the Boston Marathon.
“When I heard about the marathon in October 2010, I instantly knew that this was how I would celebrate,” she says.