A novel hematopoietic stem cell transplantation (HSCT) method utilizing ‘graft sculpting’ is being tested in a phase 1 clinical trial in patients with refractory acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) who are at the highest risk of relapse after ‘standard’ transplants. In fact, the patients in the trial don’t qualify for a standard … Read more
Waldenström’s macroglobulinemia (WM) is a blood cancer that is extremely rare, affecting around 1500 people in the US each year. About 20 percent of those cases are considered familial, meaning that many members of the same family also have some form of blood cancer, such as myeloma or lymphoma. An even smaller group — five … Read more
When Jennifer Fullerton was diagnosed with breast cancer at age 29, her mind immediately went to the worst-case scenario. “I thought I was going to die. That first day all I could think was ‘why me,’” Fullerton says. “My mom very poignantly told me, ‘Today you can say ‘why me,’ but tomorrow, ‘why not me’. And you … Read more
Brian Humberd firmly believes in an attitude of gratitude. The biotech recruiter from Melrose, Massachusetts remains eternally grateful to Dana-Farber medical oncologist David Fisher, MD, who not only recommended a life-saving stem cell transplant to treat his central nervous system (CNS) lymphoma, but whose advice enabled Humberd to become a father after his cancer treatments. … Read more
By Howard Brown As the Adult Stem Cell Transplant Program at Dana-Farber celebrates its 50th anniversary, one cancer survivor whose 1990 transplant came when the procedure was far more arduous — and far less successful — reflects on his experience. I have a four-by-three-inch plastic bag that I’ve saved for more than 32 years. It’s … Read more
When Mary Richichi flew from Boston to Utah this summer to attend her grandson’s wedding, she made sure to pack her dancing shoes. The 79-year-old was celebrating not only the happy couple’s big day, but the fact she was there to witness it, thanks to the Dana-Farber specialists who treated her breast cancer and are … Read more
When breast cancer spreads, or metastasizes, it’s more likely to travel to some parts of the body than others. The most common sites of metastasis include the bones, brain, liver, or lungs. It’s rare for patients with early-stage breast cancer, which has not spread beyond the breast or adjacent lymph nodes, to develop a brain metastasis: … Read more
Finding a lump in the groin can be frightening, but it is rare for a lump under the skin to indicate cancer. Regardless, any changes in your body should be reported to a medical professional, who can help you determine the best course of action. Where exactly is the groin? The groin makes up the … Read more
If you have been vaccinated against COVID-19, the U.S. Centers for Disease Control and Prevention (CDC) recommends different numbers of vaccines depending on if you are immunocompromised. Immunocompromised people can include people who have: As of December 2022, the COVID-19 vaccination recommendation for immunocompromised people, including active cancer patients, includes: A booster dose is another dose given … Read more
Is it normal to have a lump in the armpit? A lump in the armpit is usually not something to worry about, and the explanation for it is usually something mild and relatively harmless. Will a lump in the armpit go away? When should I see a doctor? In many cases, lumps under the armpit … Read more
The first thing you should know is that most neck lumps are not a sign of cancer. There are a host of more common causes of neck lumps, including infections, cysts, boils, and other common skin irritations. However, a neck lump can also be an early sign of several types of cancer, so if your … Read more
Got an itch that just won’t go away? Also known as pruritus (proo-rai-tuhs), itchy skin can have a wide variety of causes, including seasonal allergies and dry skin; various skin conditions, such as eczema; and even certain detergents and lotions. The good news is that itchy skin is typically not a sign of cancer. This … Read more
The most common symptom of lymphoma is the development of lumps under the skin. The lumps themselves are swollen lymph nodes, and they typically appear in the neck, armpit, or groin. Not all such lumps are a sign of lymphoma. It is normal for lymph nodes to swell as they fill with white blood cells as part … Read more
Back pain can occur for a variety of reasons not related to cancer, such as injury or arthritis; in certain circumstances, back pain can be related to cancer.
It is important to know the symptoms of kidney cancer and be aware of risk factors for the disease. Kidney cancer is more treatable the earlier it is spotted and diagnosed. However, early diagnosis remains difficult because the tumors can grow quite large without causing pain. In addition, because kidneys are located deep inside the … Read more
A simple way to stay proactive when it comes to your health is performing breast self-examinations. Performing a breast self-exam can help you understand what is normal for your body and whether there have been any changes, especially if you find a lump. Most breast lumps are not cancerous, but any noticeable changes should be … Read more
Hodgkin and non-Hodgkin lymphoma are the two main types of lymphoma, a cancer that affects the lymphatic system. The lymphatic system produces and transports white blood cells to fight infection. While they have many characteristics in common, there are some significant differences between Hodgkin and non-Hodgkin lymphoma, including the age groups they affect, how they … Read more