What Is Neoadjuvant Therapy?

Neoadjuvant therapies are drug treatments breast cancer patients receive before surgery. These treatments can help shrink tumors and make breast surgery easier for the patient and surgeon, according to Harold Burstein, MD, PhD, a breast cancer specialist in the Susan F. Smith Center for Women’s Cancers at Dana-Farber. Neoadjuvant therapy may include chemotherapy or anti-estrogen … Read more

Drug Prolongs Remissions in Some Relapsed Ovarian Cancers

Ed. note: Niraparib (Zejula) was approved by the U.S. Food and Drug Administration (FDA) on March 28, 2017, as a maintenance therapy for women with ovarian, fallopian tube, or primary peritoneal cancer. This post was originally published on Oct. 21, 2016. For women with relapsed ovarian cancer that responds to platinum-based chemotherapy, a drug that hampers … Read more

What Can Be Learned from Clinical Trials that Fail?

When a clinical trial shows that a new treatment is no better than the standard, it can be disappointing. But such outcomes yield valuable, potentially lifesaving information. Trials can “fail” if the experimental therapy doesn’t work better than current treatments. These “negative” outcomes are important for several reasons. They can spare patients false hope or … Read more