Genetic counseling now recommended for children with sarcoma

If your son or daughter has been diagnosed with a type of sarcoma – a tumor in connective tissue like muscles or bones – there are many questions: Will my child make a full recovery? What are the immediate and long-term side effects of treatment?

Most parents don’t consider whether their child will face a second cancer later in life.

However, a link between sarcomas and Li-Fraumeni syndrome, a rare condition that raises a person’s risk of developing one or more cancers to as high as 85 percent, has led genetic specialists at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center to recommend that all child sarcoma patients be offered genetic counseling for Li-Fraumeni syndrome. 

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Obesity and Cancer: What’s the Link?

There are a lot of good reasons not to gain too much weight, but you might not be aware of this one: Growing evidence links obesity to a higher risk of developing cancer, and being overweight may worsen a cancer patient’s outlook.

Although more and more studies are finding this connection, scientists haven’t uncovered the biological mechanisms by which excess pounds make normal cells more likely to turn cancerous. But they are pursuing a large number of leads, some of which may uncover new ways of fighting cancer – including losing weight.

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Blood cancer research may lead to new treatments

At this year’s American Society of Hematology Annual Meeting, Dana-Farber scientists presented major findings that could one day improve diagnosis and treatment of blood cancers, extend life, or even cure some diseases. Among the highlights: Steven Treon, MD, PhD, and his colleagues identified a gene mutation that underlies the vast majority of cases of Waldenström’s … Read more

Breast cancer specialist discusses treatment advances

Harold J. Burstein, MD, PhD, a Dana-Farber breast cancer specialist, discusses some of the important studies presented at the 2011 CTRC-AACR San Antonio Breast Cancer Symposium. The five-day meeting includes more than 1,000 scientific presentations, seminars, and posters, with a focus on emerging treatments in hard-to-treat populations, patients with metastatic breast cancer, and breast cancer … Read more