Stem Cell Transplants for Pediatric Patients: What to Know

Stem cell transplantation, otherwise known as bone marrow transplantation, is the infusion of healthy stem cells into the body to stimulate new bone marrow growth. Stem cells are vital to a person’s ability to fight infection, and stem cell transplants are performed on children whose stem cells have been damaged by disease or invasive treatments … Read more

Giving Thanks: Stem Cell Transplant Recipient Visits Donor’s Home in Germany

Charles “Chuck” Vanada has been looking forward to Thanksgiving with his family this year, but the non-Hodgkin lymphoma survivor has already experienced feelings of gratitude in 2017 more powerful – and in places more unexpected – than anything he could have imagined. In April, Vanada and his wife, Debbie, traveled from their Boston-area home to … Read more

Stem Cell Transplant Recipient Celebrates 20 Years of Life with Caregivers

Twenty years to the day after undergoing the stem cell transplant that saved him, Todd Ellison reunited with the Dana-Farber caregivers who changed his life – in more ways than one. Ellison, who was diagnosed with chronic myelogenous leukemia (CML) in his early 20s, shared handshakes and “thank you” cake with his doctors Joseph Antin, … Read more

Stem Cell Transplants and Cellular Therapies: What’s the Difference?

Donor stem cell transplants and other cellular therapies are treatment approaches that harness the immune system to fight cancer using cells from the patient or from healthy donors. What are stem cell transplants? Stem cell transplants are used to treat blood-related cancers such as leukemia, lymphoma, and multiple myeloma, as well as certain non-cancerous blood … Read more

What Care Do I Need After a Stem Cell Transplant?

A stem cell transplant can be a lifesaving treatment for patients with leukemia, lymphoma, multiple myeloma, or certain blood-related disorders. In many cases, however, transplants increase patients’ risk for an array of long-term health problems, often caused by the high doses of chemotherapy and/or radiation therapy used prior to the transplant. Dana-Farber’s Adult Stem Cell Survivorship … Read more

Autologous vs. Allogeneic Stem Cell Transplants: What’s the Difference?

A stem cell transplant is a procedure during which doctors either replace diseased or ineffective stem cells with healthy new stem cells or allow high-dose treatment for lymphoma, some testicular cancers, and other diseases. It is often lifesaving for patients with blood cancer and serious blood disorders. A person may need a transplant for a … Read more

What is Haploidentical Stem Cell Transplantation?

Medically reviewed by Joseph H. Antin, MD A treatment for patients with blood-related cancers and certain blood disorders, stem cell transplantation involves replacing a patient’s unhealthy blood-forming cells with healthy ones. Patients are first treated with chemotherapy, and sometimes radiation therapy, to wipe out or diminish the bone marrow and lymph nodes where cancers such … Read more

Tips for Celebrating the Holidays after a Stem Cell Transplant

The holidays can be a happy time of family gatherings and traditions, but the combination of extended family and friends and cold and flu season can be dangerous for patients who are immunocompromised following recent stem cell transplants to treat blood cancers including multiple myeloma, leukemia, lymphoma, and related disorders. “When transplant patients leave the … Read more

What Is a Reduced-Intensity Stem Cell Transplant?

A reduced-intensity stem cell transplant, also known as a ‘mini’ transplant, is a modified form of a procedure that replaces a patient’s blood-forming stem cells with those of a compatible donor. Mini-transplant patients receive lower doses of chemotherapy than are used in a full-intensity, or myeloablative, transplant, and, in general, receive no radiation therapy. The … Read more

FDA Approval of Defibrotide Brightens Outlook for Stem Cell Transplant Patients

Patients and Dana-Farber researchers alike welcomed this week’s Food and Drug Administration (FDA) approval of a new drug for a potentially fatal side effect of stem cell transplants. The approval means patients can receive the drug, defibrotide, as standard therapy for hepatic veno-occlusive disease (VOD) of the liver, a dangerous condition that sometimes follows transplantation … Read more

Despite Difficult Stem Cell Transplant, Teen Remains Active

Drew D’Auteuil is a 17-year-old animal-loving, skiing, rowing, volleyball- playing, honor roll student with braces and a shock of red hair. Although he may seem like a typical teen, D’Auteuil has survived rare, life-threatening complications of a stem cell transplant for severe aplastic anemia. “It’s eye-opening to realize how fragile life really is when you’re … Read more

How to Prepare Your Home for a Stem Cell Transplant Patient

Leaving the hospital is an important milestone for stem cell transplant patients, because it marks the first return home after what can often be an extended recovery. But this homecoming also requires a bit of advance preparation. That’s because stem cell transplants destroy and rebuild the immune system, leaving patients immunocompromised and thus more vulnerable … Read more