Two decades ago, Dana-Farber blood cancer researcher Sophia Adamia, PhD, left her home in Georgia, a country with a turbulent past located at the crossroads of Western Asia and Eastern Europe. Not until last May did she return to Georgia, to participate in a conference organized by the State Minister of Georgia for Diaspora Issues. … Read more
A reduced-intensity stem cell transplant, also known as a ‘mini’ transplant, is a modified form of a procedure that replaces a patient’s blood-forming stem cells with those of a compatible donor. Mini-transplant patients receive lower doses of chemotherapy than are used in a full-intensity, or myeloablative, transplant, and, in general, receive no radiation therapy. The … Read more
Stem cell transplants today can be performed on some patients well into their 70s. While advances in transplant techniques and supportive care have made transplants safer for older patients, a variety of factors influence whether the procedure is right for each individual. Your care team can help determine what is best for you. What is … Read more
Many of the secrets of why precancerous conditions sometimes become cancerous are hidden in cells’ genes. At Dana-Farber, researchers are collecting tissue samples to see if they can pry open those secrets and unlock new treatment options for certain types of blood cancers and other blood disorders. They’re also exploring whether tumor DNA floating in … Read more
When Lori Kauzlarich discovered that she had a precursor blood condition in August 2013, she sprang into action. “I was stunned,” she says. “But I decided to advocate for myself.” Precursor conditions are blood disorders that may evolve into cancers such as leukemia, Waldenström’s macroglobulinemia, and multiple myeloma. They are often asymptomatic and diagnosed incidentally … Read more
Lauren Marsden joined DKMS/Delete Blood Cancer Registry during freshman orientation at St. Anselm’s College for the same reason she majored in nursing: She wanted to help others. What she couldn’t foresee then was how this decision would intersect with her own family’s experience. Two months after Lauren’s graduation in May 2014, her father was diagnosed … Read more
Active in physical pursuits and a world traveler, Harry Beskind, MD, was surprised when he started feeling tired while on a bike ride in 2014. He had just returned home from a river trip to Portugal with his wife, and Beskind, then 82, was having trouble riding up hills on his bike. “I thought I was just … Read more
They arrived at their profession – and to Dana-Farber – on different paths, but nurses Jade Callender, RN, BSN; Jane Goldie, RN; Kaitlen Reyes, DNP, FNP; and Courtney Shea, RN, BSN, share a passion for oncology nursing. In honor of National Nurses Week May 6-12, the four share what they enjoy most about their roles. … Read more
Patients and Dana-Farber researchers alike welcomed this week’s Food and Drug Administration (FDA) approval of a new drug for a potentially fatal side effect of stem cell transplants. The approval means patients can receive the drug, defibrotide, as standard therapy for hepatic veno-occlusive disease (VOD) of the liver, a dangerous condition that sometimes follows transplantation … Read more
By Stephen Perez Cancer has a way of putting your life on hold and making you prioritize your health, treatments, and your best attempts to not feel sick through the process. While there’s never a good time for this interruption, my diagnosis came at a particularly difficult time: the second semester of my senior year … Read more
Updated April 13, 2015 Venetoclax, a new type of cancer drug known as a Bcl-2 inhibitor, is showing great promise against a poor-prognosis form of chronic lymphocytic leukemia (CLL), and could work in other cancers as well. Venetoclax, formerly known as ABT-199, attacks the protein molecule, Bcl-2, that allows cancer cells to survive despite signals … Read more
The past two years have seen a surge of new treatments for blood cancers, such as lymphoma, leukemia and multiple myeloma. Research on the genetic flaws underlying specific cancer types has led to new precision drugs such as ibrutinib and idelalisib and new immunotherapy agents that are improving outcomes in many patients with difficult-to-treat forms … Read more
“Go Dana-Farber!” Clad in her brightly-colored team singlet, Sigrid Wheatley loved hearing shouts of encouragement while running the B.A.A. Half Marathon® in Boston last October in support of Dana-Farber and the Jimmy Fund. When she took on her first full marathon for the same beneficiary this April, she heard the cheers again – and even … Read more
By Dave Lafreniere I rode in my first Pan-Mass Challenge (PMC) the day after my mother died. She was a two-time breast cancer survivor who developed an unrelated, rare ocular melanoma while I was training. She passed away in the early morning of August 2, 2002, as I sat by and held her hand. After … Read more
By Eric Bender Multiple myeloma is a poster child for recent advances in treatment: In the past decade, the U.S. Food and Drug Administration (FDA) approved no fewer than nine treatments for the blood cancer, and several more drug approvals appear to be near. Not coincidentally, multiple myeloma is also a popular target that researchers … Read more
Updated Oct. 28, 2015 Almost as long as scientists have known of the existence of viruses, they’ve dreamed of using the tiny pathogens as a weapon against cancer. Now, as a result of advances in genetic engineering and insights into the workings of the immune system, science is giving substance to the dream. A variety … Read more
Mindfulness meditation is a simple, effective technique for relieving stress and focusing on the present, whether you’re a current cancer patient, a longtime survivor, or even “a fidgety news man.” This was the message delivered by Dan Harris, correspondent and co-anchor for ABC’s “Nightline” and “Good Morning America Weekend,” during the keynote speech at the … Read more
Stem cell transplantation can be a life-saving treatment option for patients with blood cancers or disorders. The procedure, sometimes called bone marrow transplantation, replaces bone marrow that doesn’t work correctly or has been damaged by disease. We spoke with Joseph Antin, MD, chief of the Stem Cell Transplantation Program at Dana-Farber/Brigham and Women’s Cancer Center, … Read more
As 2014 comes to a close, we’re taking a look back at some of our favorite videos from the last year: Tom Brokaw: What it Means to Have Cancer NBC News’ Tom Brokaw, who was diagnosed with multiple myeloma in August 2013, stopped by Dana-Farber in November. We talked with him about his cancer experience … Read more
In the treatment of blood cancers and disorders, doctors and researchers are focusing their sights on the immune system and how to bolster its ability to fight off diseases like leukemia, lymphoma and multiple myeloma. “Understanding how you control the immune system is a big theme in treatment for these diseases,” says David A. Williams, … Read more