Stem cell transplants today can be performed on some patients well into their 70s. While advances in transplant techniques and supportive care have made transplants safer for older patients, a variety of factors influence whether the procedure is right for each individual. Your care team can help determine what is best for you. What is … Read more
Many of the secrets of why precancerous conditions sometimes become cancerous are hidden in cells’ genes. At Dana-Farber, researchers are collecting tissue samples to see if they can pry open those secrets and unlock new treatment options for certain types of blood cancers and other blood disorders. They’re also exploring whether tumor DNA floating in … Read more
When Lori Kauzlarich discovered that she had a precursor blood condition in August 2013, she sprang into action. “I was stunned,” she says. “But I decided to advocate for myself.” Precursor conditions are blood disorders that may evolve into cancers such as leukemia, Waldenström’s macroglobulinemia, and multiple myeloma. They are often asymptomatic and diagnosed incidentally … Read more
For Anna Heard, the fall of 2002 was a season of change. Set to move to Boston in September to begin a master’s program at Harvard T. H. Chan School of Public Health, Heard, then 29, had a routine physical in Washington, D.C., before starting the academic year. Although her bloodwork looked “a bit funny,” … Read more
By Kathleen Barton When you get diagnosed with cancer, it kicks your butt – both the physical aspects of chemo and the general inertia that comes with this new thing you’re living with. Before my diagnosis, I was active – working, volunteering, exercising, and spending time with friends. Then some bruising and fatigue led me … Read more
Five hundred miles from her hometown in northern Virginia, newlywed Jeannie Choi, 30, and her husband were settling into to Massachusetts and their new careers in July 2015. Just three months later, their wedding vows – to support each other in sickness and in health – would be put to the test with another transformative … Read more
By Katherine Walsh When faced with something as scary and life-changing as a cancer diagnosis, the way we see the world drastically changes. My story is a literal shift – from cancer researcher to leukemia patient, and a very sick one at that. My world came to a screeching halt in September 2010, when at … Read more
On September 24, 2015, in a sixth floor room at Boston Children’s Hospital, 5-year-old Logan Lesselroth pressed the button that started the transfer of his newly harvested blood stem cells to his 3-year-old sister, Gianna. “This,” Gianna told him, “is a gift from your body.” The path to that moment and the stem cell transplant’s … Read more
Ronaldo de Oliveira was close to death. The 33-year-old father of two young children had been diagnosed with myeloid sarcoma, a rare form of leukemia that worsened despite treatment with six different chemotherapy regimens. His wife pleaded with his oncologist, Richard Stone, MD, director of the Adult Leukemia Program at Dana-Farber, to find something else … Read more
When you’re spending days on end in a hospital bed, it’s the little things that can make all the difference. That’s what Jess Moran learned when she spent 30 consecutive days in the hospital in 2014 after being diagnosed with acute lymphoblastic leukemia. Every day, Moran, then 25, would receive several cards, most from her … Read more
With new research in immunotherapy and targeted therapy, treatment options for blood cancer patients are rapidly expanding. Combination therapies have also caused much excitement among researchers and physicians, and ongoing clinical trials are continuing to look at new strategies that use multiple drugs for fighting these diseases. In this Cancer Conversations podcast episode, Irene Ghobrial, … Read more
The last two years have been very exciting for blood cancer research; many new targeted therapies and immunotherapies are improving treatment outcomes for patients with lymphoma, leukemia and multiple myeloma. “We’re starting to see a lot of hematologic malignancies benefit from immunotherapy,” says Irene Ghobrial, MD. “The excitement is there for so many trials and … Read more
Chris Potter was not a fan of flying, until a group of pilots he had never met transported him to his life-saving care team. Potter, then 42, was struggling through a relapse of acute lymphocytic leukemia in 2011. His cancer was not responding to treatment, and he required at least a temporary remission to handle … Read more
When Roy Jann was diagnosed with cancer in 2013, it never crossed his mind that he would be a model for the life-saving potential of venetoclax, a new type of cancer drug that had recently entered human testing. The first inkling that something was amiss had come a few weeks earlier, while Jann was biking … Read more
By Philip Daley As someone who has lived in New Hampshire most of my life, I’ve always enjoyed being outdoors. When my friend James Bode hiked the Pacific Crest Trail in California a few years ago, I followed his progress on his blog and thought how cool it would be to try something similar someday. … Read more
Updated April 13, 2015 Venetoclax, a new type of cancer drug known as a Bcl-2 inhibitor, is showing great promise against a poor-prognosis form of chronic lymphocytic leukemia (CLL), and could work in other cancers as well. Venetoclax, formerly known as ABT-199, attacks the protein molecule, Bcl-2, that allows cancer cells to survive despite signals … Read more
By Todd Ellison, MSW, LICSW I often tell people that the experiences I’ve had, however challenging, were necessary to make me who I am today. I am pretty happy with the person I turned out to be, and I think cancer had a lot to do with that. Back in 1997, I was living in … Read more
This post originally appeared on the Jimmy Fund Blog. In preparation for his first day of kindergarten, young Michael Sweetman visited his primary care physician. What they anticipated to be a routine checkup left Michael’s parents with more questions than answers. The very next day, the Sweetman’s visited Dana-Farber/Boston Children’s Cancer and Blood Disorder Center, … Read more
While lymphomas and lymphocytic leukemias are both blood disorders, they are not the same disease. The main difference between lymphomas and lymphocytic leukemias is the location of the cancer cells. In leukemia, they’re found primarily in the bone marrow and blood; in lymphoma, they exist mainly in the lymph system, a network of tissues and … Read more
The past two years have seen a surge of new treatments for blood cancers, such as lymphoma, leukemia and multiple myeloma. Research on the genetic flaws underlying specific cancer types has led to new precision drugs such as ibrutinib and idelalisib and new immunotherapy agents that are improving outcomes in many patients with difficult-to-treat forms … Read more