The most commonly diagnosed blood cancers are non-Hodgkin lymphoma, chronic lymphocytic leukemia, acute myeloid leukemia, acute lymphoblastic leukemia, and multiple myeloma. Here’s what you need to know about each type of cancer. Non-Hodgkin lymphoma Non-Hodgkin lymphoma (NHL) is a type of cancer that forms in the lymph system, part of the body’s immune system. There … Read more
Precursor conditions are early phases of diseases that may develop into cancers such as lymphoma, leukemia, Waldenström’s macroglobulinemia, and multiple myeloma. Most people with precursor conditions do not experience symptoms, and since doctors rarely screen for these conditions, they are sometimes found through routine blood tests but often remain undiagnosed. “Many diagnoses are purely incidental,” says Irene Ghobrial, MD, director … Read more
When Linda Solomon, a trained medical technologist, saw the results of her routine complete blood count in 2009, she knew it wasn’t good news. Solomon, then 61, was diagnosed with stage III multiple myeloma – and given three years to survive. Several rounds of chemotherapy, two stem cell transplants, and eight years later, Solomon is … Read more
Treatment of blood-related, or hematologic, cancers is seizing on insights into the basic genetic wiring of cancer cells and the body’s system for finding and attacking those cells. Research presentations at the annual American Society of Hematology (ASH) meeting in December gave evidence of how broad, and rapid, the progress is. Targeted therapies, new combinations … Read more
In a recent Facebook Live webchat, Jacob Laubach, MD, MPP, Clinical Director of the Jerome Lipper Multiple Myeloma Center, discussed the different ways that patients can be treated with multiple myeloma, as well as exciting avenues of treatment, such as combination therapy.
Multiple myeloma is a type of cancer that begins in plasma cells — cells in the bone marrow, that, under normal circumstances, are involved in our immune defense system and produce antibodies. In multiple myeloma, too many plasma cells (myeloma cells) build up in the bone marrow. The presence of these tumor cells in the … Read more
By Deb Osborne On that beautiful day in October, filled with all the excitement life has to offer, I didn’t realize how important those words would become. Caught up in the wonderment of our wedding day, the magnitude of those words did not resonate with me until seven years ago when my husband was diagnosed … Read more
Many of the secrets of why precancerous conditions sometimes become cancerous are hidden in cells’ genes. At Dana-Farber, researchers are collecting tissue samples to see if they can pry open those secrets and unlock new treatment options for certain types of blood cancers and other blood disorders. They’re also exploring whether tumor DNA floating in … Read more
When Lori Kauzlarich discovered that she had a precursor blood condition in August 2013, she sprang into action. “I was stunned,” she says. “But I decided to advocate for myself.” Precursor conditions are blood disorders that may evolve into cancers such as leukemia, Waldenström’s macroglobulinemia, and multiple myeloma. They are often asymptomatic and diagnosed incidentally … Read more
Lauren Marsden joined DKMS/Delete Blood Cancer Registry during freshman orientation at St. Anselm’s College for the same reason she majored in nursing: She wanted to help others. What she couldn’t foresee then was how this decision would intersect with her own family’s experience. Two months after Lauren’s graduation in May 2014, her father was diagnosed … Read more
Active in physical pursuits and a world traveler, Harry Beskind, MD, was surprised when he started feeling tired while on a bike ride in 2014. He had just returned home from a river trip to Portugal with his wife, and Beskind, then 82, was having trouble riding up hills on his bike. “I thought I was just … Read more
With new research in immunotherapy and targeted therapy, treatment options for blood cancer patients are rapidly expanding. Combination therapies have also caused much excitement among researchers and physicians, and ongoing clinical trials are continuing to look at new strategies that use multiple drugs for fighting these diseases. In this Cancer Conversations podcast episode, Irene Ghobrial, … Read more
The last two years have been very exciting for blood cancer research; many new targeted therapies and immunotherapies are improving treatment outcomes for patients with lymphoma, leukemia and multiple myeloma. “We’re starting to see a lot of hematologic malignancies benefit from immunotherapy,” says Irene Ghobrial, MD. “The excitement is there for so many trials and … Read more
The past two years have seen a surge of new treatments for blood cancers, such as lymphoma, leukemia and multiple myeloma. Research on the genetic flaws underlying specific cancer types has led to new precision drugs such as ibrutinib and idelalisib and new immunotherapy agents that are improving outcomes in many patients with difficult-to-treat forms … Read more
By Eric Bender Multiple myeloma is a poster child for recent advances in treatment: In the past decade, the U.S. Food and Drug Administration (FDA) approved no fewer than nine treatments for the blood cancer, and several more drug approvals appear to be near. Not coincidentally, multiple myeloma is also a popular target that researchers … Read more
Updated Oct. 28, 2015 Almost as long as scientists have known of the existence of viruses, they’ve dreamed of using the tiny pathogens as a weapon against cancer. Now, as a result of advances in genetic engineering and insights into the workings of the immune system, science is giving substance to the dream. A variety … Read more
By Elise Renner There’s a 1-in-12 chance that this is the month yours or your loved one’s cancer is recognized—odds better than the survival rates for some of these diseases. Some months, like October, boast big names like breast cancer. Others, like September, are crowded with lesser-known branches of the disease. “Cancer apparel,” including ribbons … Read more
As 2014 comes to a close, we’re taking a look back at some of our favorite videos from the last year: Tom Brokaw: What it Means to Have Cancer NBC News’ Tom Brokaw, who was diagnosed with multiple myeloma in August 2013, stopped by Dana-Farber in November. We talked with him about his cancer experience … Read more
In the treatment of blood cancers and disorders, doctors and researchers are focusing their sights on the immune system and how to bolster its ability to fight off diseases like leukemia, lymphoma and multiple myeloma. “Understanding how you control the immune system is a big theme in treatment for these diseases,” says David A. Williams, … Read more
By Thomas Kochanek, PhD When we think of chemotherapy, most of us imagine a cancer patient hooked up to an IV in a hospital setting, getting his or her treatment through infusion. While this image is accurate, cancer treatment increasingly takes place at home, as patients receive oral chemotherapy or other types of anti-cancer drugs through … Read more