As September marks Leukemia and Lymphoma Awareness Month, we look at some important facts about adult leukemia:
1. What are the different types of leukemia?
Leukemia is a cancer of the blood. Main types of leukemia include:
- Acute Myeloid Leukemia (AML) – AML causes the bone marrow to produce immature white blood cells (called myeloblasts). As a result, patients may have a very high or low white blood cell count, and low red blood cells and platelets.
- Chronic Lymphocytic Leukemia (CLL) – CLL is the second most common type of leukemia in adults. It is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell).
- Acute Lymphocytic Leukemia (ALL) – (ALL) is a type of leukemia in which the bone marrow makes too many immature lymphocytes. Similar to AML, the white blood cells can be high or low and oftentimes the platelets and red blood cells are low. This form of leukemia is more common in children than adults.
- Chronic Myelogenous Leukemia (CML) – CML is usually a slowly progressing disease in which too many mature white blood cells are made in the bone marrow.
2. What are the symptoms of leukemia?
People with adult leukemia may experience fever, fatigue, bruising easily, shortness of breath, pain or feeling of fullness below the ribs, appetite loss, and weight loss.
3. What are the risk factors for developing leukemia?
While studies have shown men to be more at risk than women, some other risk factors include older age, smoking, having had chemotherapy or radiation exposure in the past, and having certain genetic disorders, such as Down syndrome.
4. How do doctors test for leukemia?
While test procedures vary based on the type of leukemia, the two most common procedures are the complete blood count (CBC) test and the bone marrow aspiration biopsy.
CBC is a procedure used to check the red blood cell and platelet counts, the number and type of white blood cells, the amount of hemoglobin in the blood, and the amount of blood made up of red blood cells. A bone marrow aspiration biopsy involves removing a sample of bone marrow, blood, and a small piece of bone by inserting a needle into the hipbone or breastbone. The sample is then examined for abnormal cells.
5. How is leukemia treated?
Patients may also consider treatment through a clinical trial. Dana-Farber currently has more than 30 clinical trials for adult leukemia. A national list of clinical trials is available at clinicaltrials.gov.
For more information on adult leukemia, visit the website for the Dana-Farber/Brigham and Women’s Cancer Center Adult Leukemia Program.