The body is continuously supporting the state of healing and growth — a vital function for human survival. But it can easily be taken advantage of by cancer. Angiogenesis, a process that helps the body heal by creating new capillary connections that deliver oxygen and nutrients within the body, can be hijacked to grow tumors. Drugs that block the process of blood-vessel creation, known … Read more
Along with surgery, chemotherapy and radiation therapy have long been a mainstay of cancer treatment. It uses high-energy waves or particles such as X-rays, electrons, protons, or alpha particles, to destroy or damage tumor cells. Radiation creates small breaks within the DNA of cancer cells, preventing the cells from growing and dividing, and often causing … Read more
A cancer clinical trial is a research study that is designed to test new ways to treat cancer. Trials test a range of possibilities, from treatment, devices, and diagnostics to screening, approaches to prevention, and other forms of intervention. Clinical trials determine if a given intervention is safe and effective and are essential for improvements in cancer medicine. “All of the medicines and approaches that we use to treat cancer are available because they … Read more
Under a microscope, normal adipose cells – which make up the body’s fatty tissue – look a bit like densely packed raindrops on a windshield. Each cell is filled with fat and is highly biologically active, regulating both metabolism and immunity. Liposarcoma, a cancer subtype that affects adipose tissue, perturbs these essential activities. In some … Read more
On the surface, it might appear that Meghan McLyman and Jay Wood don’t have much in common. McLyman is a mother and professor who teaches dance, and Wood is a stay-at-home father and former architect. They came to Dana-Farber for different reasons — McLyman had breast cancer and Wood was diagnosed with prostate cancer — … Read more
Clinical trials assess the safety and efficacy of new cancer drugs or drug combinations. The data and learnings these studies collect help regulators determine if the treatments should be approved and made broadly available to patients. Clinical researchers conduct clinical trials at cancer institutes, medical centers, clinics, and hospitals worldwide, all under strict guidelines. Many … Read more
Advances in cancer treatments depend on clinical trials of new drugs and other therapies. Nearly all cancer drugs in use today were tested in clinical trials. But in the United States, only 3 percent of cancer patients participate in these studies. Part of the reason is that there are many myths and misunderstandings that can keep patients … Read more
The American Cancer Society 2025 Facts and Figures report contained alarming information about cancer rates in young women. Women under 50 are getting cancer more frequently than men of the same age. In 2022, for every young man who got cancer, about 1.5 young women did. Now that number is closer to 1.8. The cause … Read more
In December 2023, a space opened in a clinical trial at Dana-Farber of a novel targeted drug. Rosemary Conway, 68, who had stage IV lung cancer, was eager to fill it. She had been waiting nearly six years for a trial of a medicine that would target a specific genetic mutation driving the growth of … Read more
Just like genetic and lifestyle factors, the composition of breasts can affect a person’s risk of developing breast cancer in their lifetime. Although it’s not yet known why, people with dense breasts have a higher risk for breast cancer. Breast density is a measure of how much glandular and fibrous tissue there is in the … Read more
When Sandra Noack returned home from a visit to Bogota, Colombia, to visit her family, there was a letter waiting for her. It was a leaflet sent via the Massachusetts Department of Public Health describing a clinical trial at Dana-Farber Cancer Institute for Latina and Hispanic breast cancer survivors. The trial didn’t involve any medicine. … Read more
What is chemotherapy? Chemotherapy is a powerful group of medicines that are used to treat cancer throughout the body. Chemotherapy (chemo) work by a variety of different mechanisms, but their general effect is to slow or stop the growth of cancer cells, which divide and grow quickly. The most common ways chemo may be given include intravenous (IV), … Read more
Medically reviewed by Martha Wadleigh, MD Leukemia arises from malfunctions in stem cells within the bone marrow that cause abnormal white blood cells to flood into the bloodstream. Leukemias are classified as either myelogenous (also called myeloid) or lymphocytic, depending on which types of white blood cells are affected. What is the difference between these types … Read more
In a small percentage of women, a painful breast lump turns out to be cancer.
More than 60,000 new cases of adult leukemia are diagnosed in the U.S. each year. Although it is one of the more common childhood cancers, leukemia occurs more often in older adults. How does leukemia develop in adults? Leukemia is a cancer of the body’s blood-forming tissues that results in large numbers of abnormal or immature white blood … Read more
Aspirin is a non-steroidal anti-inflammatory drug (NSAID) that is commonly used to reduce fevers and relieve mild to moderate pain deriving from muscle aches or strains, toothaches, headaches, and symptoms of the common cold. Research so far suggests that taking a small dose of daily aspirin over a period of years can reduce the risk … Read more
Medically reviewed by Peter C. Enzinger, MD Barrett’s esophagus is a complication of gastroesophageal reflux disease, or GERD, and can sometimes be a precursor for esophageal cancer. The condition occurs when the tissue lining the esophagus (the tube that carries food from the mouth to the stomach) begins to resemble tissue that lines the intestines … Read more
The most commonly diagnosed blood cancers are non-Hodgkin lymphoma, chronic lymphocytic leukemia, acute myeloid leukemia, acute lymphoblastic leukemia, and multiple myeloma. Here’s what you need to know about each type of cancer. Non-Hodgkin lymphoma Non-Hodgkin lymphoma (NHL) is a type of cancer that forms in the lymph system, part of the body’s immune system. There … Read more
The holidays can be a festive time, but for people dealing with cancer, they can also be stressful and full of anxiety. For many patients and their families, the thought of preparing for the season may be met with mixed emotions. And while parties and gift-giving often go hand-in-hand with the holiday season, you might … Read more
Human papillomavirus (HPV) is a virus that can cause abnormal tissue growth and other changes to cells. It can be spread through skin-to-skin contact during sexual activity, and it can be carried by all sexes. There are over 100 different types (or strains) of the virus, which are considered either “low-risk” (because they cause warts) … Read more