Hodgkin Lymphoma: The Latest in Treatment and Research

Medically reviewed by Philippe Armand, MD, PhD, and Margaret A. Shipp, MD Hodgkin lymphoma (HL) is a cancer that begins in white blood cells called lymphocytes, which play a significant role in the body’s immune system against disease. There have been major advances in the treatment of in the past several years. A two-in-one drug … Continued

Lung Cancer Screening Discussed Less with Women Patients, Study Finds

Women who are at high risk for lung cancer based on smoking history are less likely than men to have discussions with their doctors about potentially life-saving early detection screening, a new study has found. In a 2017 survey, women were 32% less likely to report having a lung cancer screening discussion with a provider … Continued

Standing up Against Multiple Myeloma Starts with a PROMISE

In 2011, Diane Dike, PhD, lost her mother to complications from multiple myeloma — a cancer of the bone marrow involving plasma cells. The pair were always close, and even share the same birthday: October 23. The illness and death of her mother was extremely difficult for the whole family, Dike says. One of the most … Continued

Colorectal Cancer: Risk Factors, Treatment, Symptoms, and More

Medically reviewed by Jeffrey A. Meyerhardt, MD, MPH Colorectal cancer forms in the tissues of the colon or rectum, which make up the large intestine. The colon and rectum are part of the body’s digestive system, which is made up of the esophagus, stomach, and the small and large intestines. The first six feet of … Continued

What Are the Signs and Symptoms of Throat Cancer?

Throat cancer is a type of head and neck cancer that may affect the larynx, the area of the throat used for speaking; the nasopharynx, the area of the throat behind the nose; or the oropharynx, the middle part of the throat. If you experience any of the symptoms described below, contact your doctor, who … Continued

Hodgkin Lymphoma Patient Aims to Lessen Cancer Stigma

Chloe Svolos is a social butterfly. When she isn’t working in the fundraising office for Dana-Farber’s Jimmy Fund, the 26-year-old is spending time with family, going out with friends, hanging out with her boyfriend, Luke, or traveling. She also recently completed treatment for lymphoma — so she’s still adjusting to her “new normal.” But in … Continued

What’s the Difference Between UVA and UVB Rays?

Medically reviewed by Elizabeth Buchbinder, MD While the warmth of sunlight can be inviting after cold winter months, it is important to remember healthy habits to keep your skin safe in the sun. Prolonged and frequent sun exposure without the proper protection can result in an uncomfortable sunburn at best and significant skin damage at … Continued

Young Mom with Metastatic Breast Cancer Fights for Other Patients

Julia Maues was excited to find out she was pregnant — and then she was diagnosed with breast cancer. She went through chemotherapy and delivered a healthy baby boy, but shortly after the birth, she learned that the cancer had spread throughout her body. She would need lifetime of treatment for metastatic breast cancer. The … Continued

Is Kidney Cancer Genetic?

Medically reviewed by Bradley McGregor, MD Kidney cancer occurs when the cells of the kidney acquire abnormal mutations in their DNA and then multiply. These cells may accumulate and form a tumor; in some cases, they metastasize and spread elsewhere in the body. Can I inherit kidney cancer? A family history of kidney cancer does … Continued

New Drug Target Found in Subset of Metastatic Prostate Cancers

Medically reviewed by Himisha Beltran, MD Prostate cancer, when diagnosed early, can be a very treatable disease. Even advanced prostate cancer has treatment options. But some advanced, metastatic prostate cancers become resistant to standard therapies by shapeshifting into a different type of cancer, called small cell neuroendocrine prostate cancer. These neuroendocrine tumors tend to be … Continued

For Stem Cell Recipient, Meeting Donor Proves Fruitful Experience

As a fruit and vegetable farmer, Douglas Young measures his life’s work by the seasons. Since receiving a stem cell transplant for his rare blood cancer, he has been able to enjoy more harvests than he once thought possible — inspiring him to seek out the stranger responsible for saving his life. In spring 2019, … Continued

Metastatic Breast Cancer: A Comprehensive Guide

Medically reviewed by Sara Tolaney, MD, MPH Metastatic breast cancer (also referred to as advanced stage or stage IV breast cancer) is breast cancer that has spread (or metastasized) from the breast and adjacent lymph nodes to other parts of the body, such as the lungs, bones, brain, or liver. Why does breast cancer spread? … Continued

What is the Difference Between B-cell Lymphoma and T-cell Lymphoma?

Medically reviewed by Eric Jacobsen, MD Lymphoma comes from a type of immune cell called a lymphocyte, which is important in helping your body fight infection. The two main types of lymphocytes are B lymphocytes (B-cell) and T lymphocytes (T-cell), and each has a slightly different function in the immune system. Each can also give … Continued

What Does a Lymphoma Lump Feel Like?

Medically reviewed by Eric Jacobsen, MD One symptom of lymphoma can be the development of lumps under the skin, usually in the neck, armpit, or groin. The lumps have a rubbery feel and are usually painless. Not all such lumps are a sign of lymphoma, but when they occur at these sites, it’s advisable to … Continued

What’s the Difference Between Outpatient Stem Cell Transplants and Inpatient Transplants?

Reduced-intensity stem cell transplants, which don’t require the traditional week-long hospital stay, are offered to qualified patients at many cancer treatment centers across the country, including Dana-Farber/Brigham and Women’s Cancer Center. These outpatient transplants (also known as ambulatory transplants) are identical in virtually every respect to those performed on an inpatient basis, with the exception … Continued

Facing Ovarian Cancer, a Doctor Becomes the Patient

By Luisa Stigol, MD, FAAP I was a 74-year-old pediatrician in practice with a multi-specialty group associated with Boston Children’s Hospital. Forty years after becoming a doctor, I still loved learning new things and sharing them with my patients. Then I was diagnosed with ovarian cancer — and suddenly, a big wall separated me from … Continued

One Big Family: Transplant Recipient Meets his Donor

For most of his life, Jim Calhoun never paid attention to college football; his football fandom started and ended with the New York Giants. This year, however, he’ll be closely following the team at Tulane University — in particular, the offensive lineman who saved his life. In 2017, Calhoun, now 45, was diagnosed with acute … Continued

Is BRCA-Positive Breast Cancer Treated Differently From BRCA-Negative?

About 5 to 10% percent of women with breast cancer have an inherited mutation in the BRCA1 or BRCA2 gene, which puts them at greater risk for developing breast and ovarian cancers. For most women diagnosed with early-stage breast cancer, having a BRCA mutation doesn’t affect how the cancer itself is treated. But the presence … Continued

What is the Difference Between Gene Therapy and Immunotherapy?

Gene therapy and immunotherapy are both types of treatment for cancer and other diseases, and they have some points at which they intersect. But ultimately they represent different approaches to disease therapy. Most diseases aren’t caused by a single mutant gene — an alteration in the DNA sequence — but some mainly rare, inherited disorders, … Continued

New therapies spark leap in treatment of AML in adults

In just over a year, the treatment of acute myelogenous leukemia (AML) in adult patients has undergone something of a revolution. Since mid-2017, the U.S. Food and Drug Administration has approved nine new targeted therapies for the disease, in contrast to none during the previous 12 years. The approvals amount to a “game-changer for how … Continued