A Year of Advances in Genitourinary Cancer 

Dana-Farber’s genitourinary cancer team is devoted to research that will advance patient care and improve patient’s lives. Recently, that research — all of it years in the making — has paid off with major achievements.  This includes:  “We are constantly striving to improve the treatment and diagnosis of genitourinary cancers,” says Toni Choueiri, MD, director … Read more

What is a Menin Inhibitor?

Menin, a protein located in the nucleus of various human cell types, often functions as a tumor suppressor by inhibiting excessive cell growth and division. It facilitates a complex of proteins involved in a cellular process called histone methylation, where chemical units called methyl groups are added to histone proteins that anchor DNA, thereby activating … Read more

Expanding Options for Patients with Ovarian Cancer 

In 2021, a novel drug called belzutifan was approved by the U.S. Food and Drug Administration (FDA) to treat clear cell renal cell carcinoma, a form of kidney cancer. Since then, Dana-Farber clinical investigator Panos Konstantinopoulos, MD, PhD, has wanted to launch a clinical trial of the drug for clear cell ovarian cancer.  That vision … Read more

Lynch Syndrome Center Guides Family Throughout Cancer Journey 

The Scragg family always knew it was a possibility, but it still came as a shock.  It was August 2021, and Mark Scragg, then 33, was undergoing treatment for stage 4 stomach cancer. After just three months of chemotherapy and immunotherapy, scans showed no sign of the tumor first discovered in his stomach that spring … Read more

Breast Cancer Survivor Provides Textured Wig Options to Women of Color 

In the midst of a lumpectomy, chemotherapy, and radiation for ​​breast cancer, Dianne Austin thought finding a wig to cover her balding head would be easy. She quickly learned otherwise.  As a Black woman, Austin desired a wig that resembled her tightly coiled, kinky and curly hair. This was 2015, and although several hospitals near … Read more

Artist Explores the Renewal and Healing of Stem Cell Transplants 

In 2023, Denise “Necee” Regis was brought face to face with her old art studio building on Brookline Avenue. As she walked by, she was able to identify the window that belonged to the room where she once spent the late 70s and early 80s working on a Master of Fine Arts at the Massachusetts … Read more

Dana-Farber Researchers Share Latest Blood Cancer and Blood Disorder Research

Dana-Farber physician-scientists presented results of more than 100 research studies at the 66th American Society of Hematology (ASH) annual meeting. Scientists shared findings across a range of hematologic disorders, underscoring the Institute’s dedication to innovation in hematologic oncology research, advances in early disease detection and intervention, and improving patient outcomes.   ASH is the world’s most comprehensive hematology … Read more

Grandmother Continues Life of Adventure on Endometrial Cancer Clinical Trial  

Roberta “Bert” Green is a woman with a full and busy life. When not driving across the country with her husband, Ralph, in their RV, she alternates between paddle boarding, walking, e-biking, and skiing with the changing seasons around her rural Vermont home. Retired after a long career as a school neuropsychologist, she also makes … Read more

Clinical Trials in AML Seek to Eliminate ‘Leftover’ Cells That Persist After Treatment

Over the last decade, significant strides have been made in understanding the molecular underpinnings of acute myelogenous leukemia (AML) in adults, which has led to better drugs and better treatment outcomes for patients. This shifting landscape now makes it possible for cancer researchers and providers to ask, “How can we do better?” Dana-Farber medical oncologist … Read more

State Rep Stays Committed to Constituents During Pancreatic Cancer Treatment 

Ann-Margaret Ferrante likes a good fight. The daughter and granddaughter of Gloucester, Mass. fishermen has long devoted herself to helping those in and around her hardy hometown, first as a lawyer, and since 2009 as a member of the Massachusetts House of Representatives.   For the last three years, however, Ferrante has had to balance her … Read more

Breast Cancer and Young People of Asian and Pacific Islander (AAPI) Descent: What You Need to Know 

Between 2000 and 2021, breast cancer rates in people under 50 of Asian or Pacific Islander decent rose by nearly 50%, from 36 to 55 cases per 100,000, with sharper increases between 2020 and 2021. Rates of breast cancer in young people are known to be rising in general, but this rate increase, according to … Read more

What You Need to Know About Rising Pancreatic Cancer Rates 

A recent analysis of pancreatic cancer statistics in the United States has found that the incidence of pancreatic cancer is increasing faster in younger adults than among older adults. Though this finding is cause for further investigation, the incidence overall remains low.   “This is still a rare cancer in young people,” says Asaf Maoz, MD, … Read more

Study Highlights Unique Needs of Young Adults with Colorectal Cancer

Clinicians and researchers have recognized a disturbing trend in recent years: colorectal cancer (CRC) in young people is skyrocketing. In individuals under the age of 50, the incidence of CRC has increased about 2% each year since the 1990s, and, according to the American Cancer Society, is now the leading cause of death in males … Read more

Study of Inherited Prostate Cancer Genetics in Africa Highlights Importance of Research

The genetic landscape of prostate cancer susceptibility in Africa is, like the continent itself, a picture of sweeping diversity, the largest study of the phenomenon concludes.  The findings, published in the journal Nature Genetics, are an important step in unravelling why prostate cancer rates are highest in men of African descent, whether they live in … Read more

With Dana-Farber’s Help, Grandmother Becomes Great Grandmother 

Six years ago, Ina Kornetsky was looking forward to a new chapter in her life. The lifelong teacher had most recently worked with older adults before retiring, and she had a deep understanding of the kind of life she wanted as she approached 90. She was preparing to move from Stoughton, Mass. into a continuing … Read more

Patient Takes Steps Toward Proactive Care Following Three Cancer Diagnoses 

Elizabeth Johnston, then 37, was healthy and busy with two young children and a blossoming career running a public relations firm in Connecticut. One of her clients is the Hartford Marathon Foundation and in 2015, she decided to start running smaller stretches herself.   “I was in the best shape of my life,” Johnston recalls.   Little … Read more

For Neurodiverse Patient, New Program Provides Comfort, Allies 

Naomi Dogan, PhD, still remembers a visit to the hospital earlier this year for blood work, after joining a clinical trial for patients incurring symptoms related to polycythemia vera — one of a group of rare blood disorders known as myeloproliferative neoplasms (MPNs).   In a far corner of the large room a machine quietly hummed … Read more