Friendship Proves a Strong Foundation for Patient and Caregiver 

In 2023, Jackie Coté had just been diagnosed with metastatic breast cancer. Feeling shocked and overwhelmed, she and her friend Nancy Gill, who accompanied Coté to her appointment, silently made their way to the front desk to schedule Coté’s weekly chemotherapy. As Coté entered the appointments into her phone calendar, Gill did the same in … Read more

The Power of Long-Range Hope and Courage 

While participating in a clinical trial, Kathleen McEvoy-Schufreider, a 60-year-old communications executive living in Haverhill, Mass., traveled to Dana-Farber for scans every twelve weeks to monitor her cancer. In between appointments, it was hard to put the scans out of her mind.  “I was living in twelve-week bursts,” says McEvoy-Schufreider, who was diagnosed with early-stage … Read more

Five Things You Should Know About Aggressive Prostate Cancer 

Among cancer diagnoses, prostate cancer is relatively common, especially for those who are older than 65. Fortunately, it is often manageable with minimal interventions necessary for a substantial portion of patients. However, many prostate cancer cases can be categorized as “aggressive,” meaning it will require more extensive treatment to address or avoid metastasis (spread of the cancer).   … Read more

New Insights into Immunotherapy Targets for Pancreatic Cancer 

Cancer research often focuses on gene mutations in the parts of the human genome that produce cellular machinery called proteins. But the rest of the genome — sometimes called the “dark genome” — can also play a role.   Dana-Farber researcher William Freed-Pastor, MD, PhD, a physician-scientist in the Dana-Farber Center for Gastrointestinal Oncology and Hale … Read more

Years of Research Help Forge a New Path in Hodgkin Lymphoma Treatment  

Medical advances tend to unfold slowly over many years, fueled by successive clinical studies that build upon each other and together provide the evidence needed to change patient care. A key illustration of this point comes from a recent phase 3 clinical trial, published last October in the New England Journal of Medicine (NEJM), which … Read more

Fundraiser, Marilyn Monroe Impersonator, Snow Queen: Breast Cancer Patient Does It All 

While planning her annual breast cancer fundraiser in Hull, Mass., Ellie Destito’s friends learned some surprising news. For the first time, their friend revealed that she was living with breast cancer herself.  “They had no idea,” recalls Destito, who was first diagnosed with breast cancer back in 2008. Through the years, she was treated with … Read more

Program Specializes in Older Adults with Gastrointestinal Cancers 

Dana-Farber’s Older Adult Gastrointestinal Cancer Program specializes in treating patients who are 65 and older and have gastrointestinal cancers, such as colorectal cancer, esophageal and gastric cancer, liver cancer, neuroendocrine and pancreatic cancer.   “Older adults are richly complex and multidimensional,” says gastrointestinal and geriatric oncologist Nadine McCleary, MD, MPH, who leads the program. “They deserve … Read more

From Staff Member to Empowered Patient: A Journey with Lynch Syndrome 

In March 2016, two months before joining Dana-Farber, Sara Menendez, LAT, ATC, attended LYNKED IN, an annual one-day conference hosted by Dana-Farber’s Lynch Syndrome Center. The event gave her an opportunity to meet colleagues and learn about treatment advances, screening guidelines, and prevention efforts for Lynch syndrome, an inherited and often underdiagnosed condition that increases … Read more

Microplastics and Cancer: Your Questions Answered 

In recent decades, rates of some cancers, such as colorectal cancer, have been rising in young adults under the age of 50. One possible explanation for this rise is a parallel rise in obesity rates and changes in diet, activity levels and lifestyle.   However, says Kimmie Ng, MD, MPH, director of Dana-Farber’s Young-Onset Colorectal Cancer … Read more

A Year of Advances in Genitourinary Cancer 

Dana-Farber’s genitourinary cancer team is devoted to research that will advance patient care and improve patient’s lives. Recently, that research — all of it years in the making — has paid off with major achievements.  This includes:  “We are constantly striving to improve the treatment and diagnosis of genitourinary cancers,” says Toni Choueiri, MD, director … Read more

What is a Menin Inhibitor?

Menin, a protein located in the nucleus of various human cell types, often functions as a tumor suppressor by inhibiting excessive cell growth and division. It facilitates a complex of proteins involved in a cellular process called histone methylation, where chemical units called methyl groups are added to histone proteins that anchor DNA, thereby activating … Read more