Can Less Treatment for Colorectal Cancer Yield the Same Results? 

Colon and rectal cancer combined are the fourth most commonly diagnosed cancers.  Eighty percent of patients are diagnosed at a stage of disease when treatment is given with curative-intent.  However, treatment can have both short- and long-term side effects that may impact quality of life.   To address these concerns, investigators at Dana-Farber have led clinical … Read more

Could AI Help Doctors Predict Pancreatic Cancer? 

As a cancer imaging fellow at Dana-Farber, Michael Rosenthal, MD, PhD, spent about two years working on a radiologist’s version of paint-by-number. Together with his colleagues, he annotated 687 computed tomography (CT) scans, manually differentiating skeletal muscle from fat tissue by labelling them with different colors.   The work was part of a 2018 project to … Read more

Living Systematic Review Guides Prostate Cancer Treatment Options

As science and clinical medicine advance, oncologists increasingly face the challenge of information overload. It can be hard for oncologists, especially those in community practices who cover many cancers, to keep up with the influx of new therapies, biomarkers, and clinical trial results. The go-to solution has been the systematic review. Researchers team up to … Read more

Aspartame: What You Need to Know 

Alongside gasoline engine exhaust and radiofrequency waves from cell phones, aspartame, the sweetener found in diet sodas and many sugar-free foods, is now categorized as “possibly carcinogenic.” The decision, made by the World Health Organization (WHO) International Agency for Research on Cancer (IARC), has gotten a lot of attention.   We spoke with Timothy R. Rebbeck, … Read more

How to Stay Healthy When Air Quality Is Not

On June 7, 2023, New York City had the world’s worst air quality as smoke from Canadian wildfires drifted southward. Images of the city showed orange skies and a barely visible skyline. Air pollution is a leading cause of death worldwide and is also connected to cancer. According to the American Lung Association (ALA), long … Read more

Acquired vs. Inherited Mutations in Cancer: What You Need to Know 

A gene mutation is a change in the genetic instructions in a cell. Genes are the DNA-encoded instructions for building proteins, which are the machinery that does the work inside our cells and our bodies. Some mutations change the function of proteins in ways that increase the risk of cancer or drive its growth.   Gene … Read more

A Family Navigates Challenges of Rare Blood Cancer Called Waldenström’s Macroglobulinemia

Tom Lomaglio, Jr., learned he had a rare blood cancer called Waldenström’s Macroglobulinemia (WM) in 2000. His father, Tom, Sr., had been diagnosed in 2004, and then his sister, Diane, in 2007. They were all referred to Dana-Farber for care. When Lomaglio visited the first time, he met Steven Treon, MD, PhD, director of the … Read more

What is MRI-Guided Radiation Therapy?

Doctors use traditional radiation therapy to guide a beam of radiation toward a tumor, making every effort to minimize the effects of that radiation on surrounding healthy tissue. But some tumors are hard to treat this way because the tumors don’t stay put. They move as a patient breathes or even as they digest. MRI-guided … Read more