As a cancer imaging fellow at Dana-Farber, Michael Rosenthal, MD, PhD, spent about two years working on a radiologist’s version of paint-by-number. Together with his colleagues, he annotated 687 computed tomography (CT) scans, manually differentiating skeletal muscle from fat tissue by labelling them with different colors. The work was part of a 2018 project to … Read more
A new fad has emerged: the full-body MRI scan. The interest in this high-tech health diagnostic comes from the notion that the scan can catch health issues, including cancer, early. With a price tag of $2,000 to $2,500, they aren’t an option for many people, and they are not covered by health insurance. But are … Read more
Most forms of chemotherapy are designed to kill cancer cells. But some cancer cells survive. Those that do can cause the cancer to relapse. Dana-Farber researcher Patrick Bhola, PhD, calls these cells “bad actors.” They are up to no good. In a new paper, he describes a technique to identify potential bad actors before treatment … Read more
Certain forms of cancer and cancer treatment can affect your vision and, in rare cases, cause vision loss. At Dana-Farber, our care teams will work with you to help you understand the possibilities, know what to look for, and take action to manage any vision changes that might occur. What types of cancer can cause … Read more
As science and clinical medicine advance, oncologists increasingly face the challenge of information overload. It can be hard for oncologists, especially those in community practices who cover many cancers, to keep up with the influx of new therapies, biomarkers, and clinical trial results. The go-to solution has been the systematic review. Researchers team up to … Read more
Alongside gasoline engine exhaust and radiofrequency waves from cell phones, aspartame, the sweetener found in diet sodas and many sugar-free foods, is now categorized as “possibly carcinogenic.” The decision, made by the World Health Organization (WHO) International Agency for Research on Cancer (IARC), has gotten a lot of attention. We spoke with Timothy R. Rebbeck, … Read more
In early March of 2018, at age 58, Roger Miller went to a local doctor’s office in Maine for outpatient surgery. He’d been putting off getting what he’d thought was a cyst removed from the back of his head. During the procedure, he overheard the surgeon say, “Oh, this doesn’t look good.” Miller, who at … Read more
Black men, particularly men of West African descent, are nearly twice as likely to be diagnosed with prostate cancer than Caucasian men, and three times more likely than Asian men. They are also twice as likely as Caucasian men to die from the disease. These disparities are among the largest in cancer. What is driving … Read more
Animals — from oysters and corals to flies and mammals — encode proteins to sense their environment and share a common strategy to rally a defense. Scientists have identified a new family of immune proteins conserved across animal evolution with common features. Recent research from Dana-Farber Cancer Institute has added a new family to the … Read more
On June 7, 2023, New York City had the world’s worst air quality as smoke from Canadian wildfires drifted southward. Images of the city showed orange skies and a barely visible skyline. Air pollution is a leading cause of death worldwide and is also connected to cancer. According to the American Lung Association (ALA), long … Read more
More than seven percent of adults in the US identify as LGBTQ+, according to a 2022 Gallup poll. That’s a record high and a doubling of the percentage measured a decade earlier. People in the LGBTQ+ community can face many societal barriers, including to healthcare. According to multiple surveys, about one in three LGBTQ+ people … Read more
Over the past three decades, the number of cancer survivors has increased. That trend is expected to continue. The numbers indicate progress in the treatment of cancer, but they also underscore the importance of quality of life after cancer. “We want people to lead healthy, productive, enjoyable lives, and mobility is such an important piece … Read more
Words like “chemobrain” and “chemofog” — terms now used by patients, doctors, and scientists to describe cognitive decline that some patients experience in response to cancer therapy — didn’t exist a few decades ago. Today, however, there’s a general awareness that cancer treatments can take a toll on the brain. Oncologists don’t yet have a … Read more
A gene mutation is a change in the genetic instructions in a cell. Genes are the DNA-encoded instructions for building proteins, which are the machinery that does the work inside our cells and our bodies. Some mutations change the function of proteins in ways that increase the risk of cancer or drive its growth. Gene … Read more
Hodgkin lymphoma (sometimes called Hodgkin’s lymphoma) is a form of cancer that affects the immune system. It starts in the white blood cells, but what patients and doctors will most likely notice first is a lump in the neck, under the arm, or in the groin. How is Hodgkin lymphoma staged? Hodgkin lymphoma is staged … Read more
Ovarian cancer almost always starts in the fallopian tubes. It’s counterintuitive. Why is it called ovarian cancer if it doesn’t start there? For a long time, the ovaries were assumed to be the source because that is where the cancer is concentrated at the time of diagnosis. But about 20 years ago, researchers took a … Read more
Tom Lomaglio, Jr., learned he had a rare blood cancer called Waldenström’s Macroglobulinemia (WM) in 2000. His father, Tom, Sr., had been diagnosed in 2004, and then his sister, Diane, in 2007. They were all referred to Dana-Farber for care. When Lomaglio visited the first time, he met Steven Treon, MD, PhD, director of the … Read more
Doctors use traditional radiation therapy to guide a beam of radiation toward a tumor, making every effort to minimize the effects of that radiation on surrounding healthy tissue. But some tumors are hard to treat this way because the tumors don’t stay put. They move as a patient breathes or even as they digest. MRI-guided … Read more
Researchers in the late 1970s wanted to address challenges with a chemotherapy drug called floxuridine. It’s a form of chemotherapy invented in the 1950s that turns into its active form, 5-fluorouracil, or 5-FU, when metabolized. One challenge is that 5-FU has off-target effects, meaning it can damage healthy organs when given throughout the body. In … Read more
Cancer vaccines are a form of immunotherapy aimed at enhancing the immune system’s ability to recognize and attack cancer cells, or to protect against certain forms of cancer caused by viruses. Vaccine can help prevent some cancers There are two approved preventive vaccines directed against cancer-causing viruses. Vaccines against cancer-causing or other infectious microbes typically … Read more