Leah Christoforidis was pregnant with her fourth child when she began feeling pain in her lower back. Her doctor initially figured it was a muscle tear, but something told Christoforidis that wasn’t right, and she successfully advocated for an ultrasound. A few weeks later, Christoforidis faced a new kidney cancer diagnosis instead of a routine … Read more
New approaches to treatment are improving outcomes for patients with aggressive prostate cancer, which is prostate cancer that has spread or is at higher risk of spreading. In addition, new tests are helping guide treatment choices as more treatment options become available. Therapies used to treat aggressive prostate cancer include chemotherapy, hormone therapy, and newer … Read more
Among cancer diagnoses, prostate cancer is relatively common, especially for those who are older than 65. Fortunately, it is often manageable with minimal interventions necessary for a substantial portion of patients. However, many prostate cancer cases can be categorized as “aggressive,” meaning it will require more extensive treatment to address or avoid metastasis (spread of the cancer). … Read more
Dana-Farber’s genitourinary cancer team is devoted to research that will advance patient care and improve patient’s lives. Recently, that research — all of it years in the making — has paid off with major achievements. This includes: “We are constantly striving to improve the treatment and diagnosis of genitourinary cancers,” says Toni Choueiri, MD, director … Read more
The genetic landscape of prostate cancer susceptibility in Africa is, like the continent itself, a picture of sweeping diversity, the largest study of the phenomenon concludes. The findings, published in the journal Nature Genetics, are an important step in unravelling why prostate cancer rates are highest in men of African descent, whether they live in … Read more
Like all vaccines, prostate cancer vaccines work by stimulating the body’s immune system. Unlike vaccines for the flu, COVID-19 and other infections, which protect against disease, prostate cancer vaccines are a form of treatment. Treatment vaccines activate the immune response against cancer cells by targeting antigens – cancer-related proteins produced in greater abundance in tumor … Read more
In Zhejiang Province, China, Yijia Wang headed to his local physician to find out the source of a lower back pain that had bothered him for weeks. Results from a biopsy took several weeks, eventually revealing a diagnosis of collecting duct carcinoma, a rare cancer in the kidney. Wang’s first round of treatment with a … Read more
Bladder cancer treatment is advancing, with several approved immunotherapy options, an approved gene therapy, and an approach to cell therapy planned for testing in clinical trials at Dana-Farber. What is bladder cancer? The most common form of bladder cancer is urothelial carcinoma, in which the urothelial cells that line the bladder and urinary tract begin … Read more
Prostate cancer is the most common cancer diagnosed in men. When found early, before it has spread, patients can do extremely well. However, prostate cancer risks vary due to genetics, health care access, socioeconomics, and environmental exposures. Some groups have higher risks and worse outcomes. For example: The best way to improve your chances of … Read more
Prostate cancer is the second most common cause of cancer in men worldwide as of 2020, and cases of advanced prostate cancer continue to rise. Early detection of prostate cancer is essential for effective treatment. Dana-Farber physicians recommend having a conversation with a medical professional about screening around the age of 40, or perhaps even … Read more
In the fall of 2019, John Brazeau’s back pain got so bad that it interfered with his ability to engage in the two hobbies he loved most in his retirement on Cape Cod: golfing and clamming. Despite keeping up with physical therapy exercises meant to relieve the pain, it wasn’t diminishing. Then in 2020, Brazeau … Read more
The last thing Alan Rubin imagined he’d be doing after retiring from a successful career in financial services was helping his son run a hot dog cart. Then he was diagnosed with stage III kidney cancer, and found himself in another unexpected locale: Dana-Farber Brigham Cancer Center. Like the decision to join his son’s business … Read more
As science and clinical medicine advance, oncologists increasingly face the challenge of information overload. It can be hard for oncologists, especially those in community practices who cover many cancers, to keep up with the influx of new therapies, biomarkers, and clinical trial results. The go-to solution has been the systematic review. Researchers team up to … Read more
Although early detection and treatment advances have significantly improved survival rates for patients with prostate cancer, the majority will face some form of sexual health side effect. Addressing these physical and emotional side effects is a priority for care teams at Dana-Farber. But longstanding cultural barriers can often keep men from discussing sensitive issues like … Read more
Black men, particularly men of West African descent, are nearly twice as likely to be diagnosed with prostate cancer than Caucasian men, and three times more likely than Asian men. They are also twice as likely as Caucasian men to die from the disease. These disparities are among the largest in cancer. What is driving … Read more
People who inherit mutations in the BRCA1 or BRCA2 gene are at heightened risk for a variety of cancers, including breast, ovarian, prostate, and pancreatic. It’s estimated that one in 300-400 people in the general population carry a mutation in either of these genes. Among people of Ashkenazi (Eastern European) Jewish descent, the prevalence is … Read more
When Chuck Stravin was diagnosed with renal cell carcinoma in 2015, one of his biggest fears was not living long enough to see his four young daughters get married. The disease later metastasized to his lungs as stage IV cancer, but thanks to groundbreaking clinical trials and a care team he considers family, Stravin is … Read more
Overall, cancer death rates have declined by 33% since 1991, according to a Jan. 2023 American Cancer Society report. Multiple cancers like leukemia, melanoma, and kidney cancer have seen significant declines in mortality due to great advances in treatments. Prostate cancer rates had been on the decline for two decades, but the ACS report remarks that … Read more
Doug Kroc taught social studies for 40 years, but these days the retiree is more interested in making history than teaching it. Not the kind of events found in textbooks, but simple moments spent swimming and kayaking with his family or riding his bike along the backroads of Vermont. So when Kroc, 70, developed a … Read more
At 25, Fredrick Knight was unsure what to do when he felt an intense pain in his right testicle. He visited the local emergency room where he lived in Western Massachusetts and was told that the answer might be testicular torsion, a condition that occurs when a testicle rotates, reducing blood flow and causing pain. … Read more