Is Kidney Cancer Genetic?

Medically reviewed by Bradley McGregor, MD Kidney cancer occurs when the cells of the kidney acquire abnormal mutations in their DNA and then multiply. These cells may accumulate and form a tumor; in some cases, they metastasize and spread elsewhere in the body. Can I inherit kidney cancer? A family history of kidney cancer does … Continued

New Drug Target Found in Subset of Metastatic Prostate Cancers

Medically reviewed by Himisha Beltran, MD Prostate cancer, when diagnosed early, can be a very treatable disease. Even advanced prostate cancer has treatment options. But some advanced, metastatic prostate cancers become resistant to standard therapies by shapeshifting into a different type of cancer, called small cell neuroendocrine prostate cancer. These neuroendocrine tumors tend to be … Continued

New study uncovers strategy for defusing castration-resistant prostate cancer

Cancer is often fueled by hormones, including the male sex hormone testosterone, which spur tumor growth in most forms of prostate cancer. Doctors can defuse this destructive relationship, typically with drugs (or sometimes surgery), but frequently, the tumors adapt or evolve, devising ways to incite cancer growth even in the absence of hormone-driven signals. These … Continued

How Does Bladder Cancer Affect the Urinary System?

Urinary problems are more common among older adults, when incontinence and urinary-tract infections become more prevalent and bladder cancer risk rises. About 9 out of 10 bladder cancer patients are above the age of 55, according to the American Cancer Society. The symptoms of bladder cancer can mirror those of other conditions, so it’s important … Continued

What is Carcinoma of the Prostate?

Carcinoma of the prostate is a type of prostate cancer that occurs when normal prostate cells begin to grow uncontrollably. Carcinomas begin in the epithelial tissue—the thin tissue, like skin, that covers the linings of internal organs. Other cancers typically form in the body’s connective or supportive tissues (sarcomas), blood-forming tissue like bone marrow (leukemia), … Continued

Rugby Player-Turned-Researcher Seeks Mechanisms Behind Prostate Cancer Metastases

Leigh Ellis, PhD, once seemed destined for a career intercepting passes as a professional rugby player. Now, the Dana-Farber researcher is devising plays to intercept prostate cancer cells before they become metastatic. These tactics could also potentially slow other genitourinary diseases, including kidney cancer. Ellis’ laboratory works to better understand the underlying genetic and epigenetic … Continued

Does an Elevated PSA Level Mean I Have Prostate Cancer?

Prostate cancer­­­­ is a disease that forms in the tissues of the prostate, a male gland just below the bladder which is partly responsible for making the fluid that is part of semen. Prostate cancer forms within cells in the prostate. The disease takes a variable course from patient to patient. Some prostate cancers spread … Continued

Does BPH (Benign Prostate Hyperplasia) Lead to Prostate Cancer?

Benign prostate hyperplasia (BPH) is a common condition among men in their 60s and 80s that is caused by an enlargement of the prostate. Conflicting research poses speculation as to whether BPH actually leads to prostate cancer. Here, Mark Pomerantz, MD, a medical oncologist at Dana-Farber Cancer Institute who specializes in treating prostate cancer, clarifies … Continued

4 Common Prostate Cancer Myths, Debunked [Podcast]

Prostate cancer is a disease in which cancer forms in the prostate, a gland located just below the bladder and in front of the rectum in males. In the United States, a man has a one in five chance of being diagnosed with this disease in his lifetime. But there are still a lot of … Continued

Dana-Farber Oncologist Gears Up for First Pan-Mass Challenge

Dana-Farber’s Toni Choueiri, MD, will participate in his first Pan-Mass Challenge (PMC) bike-a-thon in August. “Considering his dedication to me and his other patients, I am not surprised that he is riding in the PMC and raising money to develop new treatments for people with my type of kidney cancer,” says a former patient of Choueiri’s.

What is Active Surveillance for Prostate Cancer?

Long-term studies of men with low-risk prostate cancer have demonstrated that active surveillance is safe and that a majority of patients can successfully forego surgery or radiation for over 10 years.

Given Months to Live, Kidney Cancer Patient Defies the Odds

Two years after being given six months to live, Mullan’s cancer is still at bay because of immunotherapy and targeted chemotherapy – and through it all, he achieved one of his dreams: graduating from Harvard Law School.

Immunopatient: One Patient’s Story of Cancer and Immunotherapy

It’s not uncommon for cancer patients to take to a pen after a diagnosis. Peter Rooney’s taken that to another level. Rooney, a former journalist and author of the book Die Free, captured his cancer journey in the new book Immunopatient: The New Frontier of Curing Cancer. The following excerpt is reprinted with permission from Immunopatient by … Continued

Benign Prostatic Hyperplasia (BPH) and Prostate Cancer: What’s the Difference?

Benign prostatic hyperplasia (BPH) and prostate cancer both involve enlargement of the prostate, the walnut-sized gland that produces fluid that makes up a portion of semen. The prostate sits below the bladder and surrounds the urethra, the tube that carries urine out of the body. When the prostate increases in size, whether due to BPH, … Continued

Cancer Treatment: A Look at How It Has Evolved in 70 Years

In 1947, when Dana-Farber Cancer Institute founder Sidney Farber, MD, set out to find a drug treatment for childhood leukemia, cancer treatment took two forms – surgery to cut out cancerous masses, and radiation therapy to burn them out. Cancers that couldn’t be removed or irradiated – either because of their position in the body, because … Continued