Prostate Cancer Patient Thriving 17 Years After Diagnosis

When he was 67 years old, Barry Polsky said “I do” for the first time in his life when he married his wife, Randi. One year later, the retired high school teacher and lifelong baseball fan was offered one of his dream jobs as a tour guide at Fenway Park. And earlier this year, at … Continued

What African American Men Need to Know About Prostate Cancer

African-Americans have a 60 percent higher incidence of prostate cancer compared to other ethnic groups, and a 150 percent higher risk of dying from it — in part because blacks tend to have a more aggressive form. They are also more likely to develop prostate cancer at an earlier age and to have a more … Continued

New Drug Target Found in Subset of Metastatic Prostate Cancers

Medically reviewed by Himisha Beltran, MD Prostate cancer, when diagnosed early, can be a very treatable disease. Even advanced prostate cancer has treatment options. But some advanced, metastatic prostate cancers become resistant to standard therapies by shapeshifting into a different type of cancer, called small cell neuroendocrine prostate cancer. These neuroendocrine tumors tend to be … Continued

New study uncovers strategy for defusing castration-resistant prostate cancer

Cancer is often fueled by hormones, including the male sex hormone testosterone, which spur tumor growth in most forms of prostate cancer. Doctors can defuse this destructive relationship, typically with drugs (or sometimes surgery), but frequently, the tumors adapt or evolve, devising ways to incite cancer growth even in the absence of hormone-driven signals. These … Continued

What is Carcinoma of the Prostate?

Carcinoma of the prostate is a type of prostate cancer that occurs when normal prostate cells begin to grow uncontrollably. Carcinomas begin in the epithelial tissue—the thin tissue, like skin, that covers the linings of internal organs. Other cancers typically form in the body’s connective or supportive tissues (sarcomas), blood-forming tissue like bone marrow (leukemia), … Continued

Rugby Player-Turned-Researcher Seeks Mechanisms Behind Prostate Cancer Metastases

Leigh Ellis, PhD, once seemed destined for a career intercepting passes as a professional rugby player. Now, the Dana-Farber researcher is devising plays to intercept prostate cancer cells before they become metastatic. These tactics could also potentially slow other genitourinary diseases, including kidney cancer. Ellis’ laboratory works to better understand the underlying genetic and epigenetic … Continued

Does an Elevated PSA Level Mean I Have Prostate Cancer?

Prostate cancer­­­­ is a disease that forms in the tissues of the prostate, a male gland just below the bladder which is partly responsible for making the fluid that is part of semen. Prostate cancer forms within cells in the prostate. The disease takes a variable course from patient to patient. Some prostate cancers spread … Continued

4 Common Prostate Cancer Myths, Debunked [Podcast]

Prostate cancer is a disease in which cancer forms in the prostate, a gland located just below the bladder and in front of the rectum in males. In the United States, a man has a one in five chance of being diagnosed with this disease in his lifetime. But there are still a lot of … Continued

What is Active Surveillance for Prostate Cancer?

Long-term studies of men with low-risk prostate cancer have demonstrated that active surveillance is safe and that a majority of patients can successfully forego surgery or radiation for over 10 years.

Benign Prostatic Hyperplasia (BPH) and Prostate Cancer: What’s the Difference?

Benign prostatic hyperplasia (BPH) and prostate cancer both involve enlargement of the prostate, the walnut-sized gland that produces fluid that makes up a portion of semen. The prostate sits below the bladder and surrounds the urethra, the tube that carries urine out of the body. When the prostate increases in size, whether due to BPH, … Continued

Cancer Treatment: A Look at How It Has Evolved in 70 Years

In 1947, when Dana-Farber Cancer Institute founder Sidney Farber, MD, set out to find a drug treatment for childhood leukemia, cancer treatment took two forms – surgery to cut out cancerous masses, and radiation therapy to burn them out. Cancers that couldn’t be removed or irradiated – either because of their position in the body, because … Continued

Can Immunotherapy Be Used to Treat Prostate Cancer?

Prostate cancer can be treated by immunotherapy, and it was the first form of cancer for which a vaccine therapy – a treatment that stimulates the immune system to attack a disease – was approved by the U.S. Food and Drug Administration (FDA). That vaccine, called Provenge, was cleared by the FDA in 2010 to treat advanced … Continued

What Are The Symptoms of Prostate Cancer?

Prostate cancer is a disease in which cancer forms in the tissues of the prostate, a male gland just below the bladder and in front of the rectum. Prostate cancer is rare in men younger than 50 years of age, and the chance of developing prostate cancer increases as men get older. In the United … Continued

Online Tool Offers Guidance for Men with Non-Metastatic Prostate Cancer

Men diagnosed with non-metastatic prostate cancer now have access to a new tool on the TrueNTH USA website to help them prepare for their first meeting with a cancer physician. The tool, called Personal Patient Profile-Prostate (P3P), was created by Dana-Farber researchers and is now available to all men with non-metastatic prostate cancer though TrueNTH … Continued

What Is ‘Watchful Waiting’ and When Is it Right for Prostate Cancer?

According to the American Cancer Society, more than 180,000 men will be diagnosed with prostate cancer this year, with African American men 60 percent more likely to develop the disease than other ethnic groups. Fortunately, the vast majority of prostate cancer diagnoses will be a slow-growing, highly treatable form of the disease. For many men diagnosed … Continued

Cancer Conversations Podcast—Episode #16: The Latest in Prostate Cancer Treatment and Research

Prostate cancer affects 230,000 men each year. Although diagnoses are increasing worldwide, most people die with prostate cancer and not of prostate cancer, according to Mark Pomerantz, MD, a medical oncologist in Dana-Farber’s Lank Center for Genitourinary Oncology. In this Cancer Conversations podcast episode, Pomerantz discusses genetics, risk factors, and the controversy surrounding the PSA … Continued

Do PSA Levels Change with Age?

Medically reviewed by Mark Pomerantz, MD Prostate-specific antigen, or PSA, is a protein naturally produced by the prostate gland in men. Because prostate cancer can increase the level of PSA in the blood, many doctors and professional organizations recommend that men over age 50 receive a PSA test in conjunction with a digital rectal exam … Continued

The Latest in Prostate Cancer Research and Treatment

Prostate cancer is the most common cancer affecting men in the United States, after skin cancer. Yet, “most men die with prostate cancer, not of prostate cancer,” says Mark Pomerantz, MD, a medical oncologist in Dana-Farber’s Lank Center for Genitourinary Oncology, who recently shared the latest in prostate cancer research and treatment during a live … Continued

Does Cycling Increase Risk for Testicular or Prostate Cancer?

Since professional cyclist Lance Armstrong was diagnosed with testicular cancer in 1996, many men have wondered about the connection between cycling and testicular cancer, as well as prostate cancer. While a number of studies have looked into a link between the sport and cancer, the findings to date are inconclusive, says Mark Pomerantz, MD. “This … Continued