Medically reviewed by Ann S. LaCasce, MD, MMSc Mantle cell lymphoma is a rare, often aggressive form of non-Hodgkin lymphoma (NHL), a cancer that involves white blood cells known as lymphocytes, which help protect the body from disease. It is named for its origins in the mantle zone — a ring of cells within the … Continued
Steve Kelley is the quintessential glass half-full guy. Still, he realizes his reaction to learning he had an extremely rare cancer known as central nervous system (CNS) lymphoma may seem unusual. A few weeks after his June 2018 diagnosis, Kelley, then 64, gathered his family and friends together. He didn’t want to focus negatively on … Continued
Medically reviewed by David M. Weinstock, MD, and Eric Jacobsen, MD By banding together to study the basic biology and vulnerabilities of T-cell lymphoma, scientists at several major cancer research centers have sparked a surge of clinical trials of promising treatments for the disease. The string of new trials, some already open, some expected to … Continued
Jerry Jalbert is always up for new adventures. He did not expect that non-Hodgkin lymphoma (NHL) would be one of them, but with the help of CAR T-cell therapy that keeps his cancer at bay, the 73-year-old professional photographer-turned-baker-turned-forest checkpoint operator is continuing to enjoy life’s many journeys alongside his wife, Ethel. “We are not … Continued
In May 2018, Tyler Goodwin underwent CAR T-cell therapy for follicular non-Hodgkin lymphoma (NHL). While he was having preparatory chemotherapy for the procedure, a surprise visitor to his hospital bedside provided a powerful reminder of why this promising new cancer treatment was so important to him. “It was my daughter Theresa, all made up for … Continued
Medically reviewed by Philippe Armand, MD, PhD, and Margaret A. Shipp, MD Hodgkin lymphoma (HL) is a cancer that begins in white blood cells called lymphocytes, which play a significant role in the body’s immune system against disease. There have been major advances in the treatment of the disease in the past several years. A … Continued
Chloe Svolos is a social butterfly. When she isn’t working in the fundraising office for Dana-Farber’s Jimmy Fund, the 26-year-old is spending time with family, going out with friends, hanging out with her boyfriend, Luke, or traveling. She also recently completed treatment for lymphoma — so she’s still adjusting to her “new normal.” But in … Continued
Medically reviewed by Eric Jacobsen, MD Lymphoma comes from a type of immune cell called a lymphocyte, which is important in helping your body fight infection. The two main types of lymphocytes are B lymphocytes (B-cell) and T lymphocytes (T-cell), and each has a slightly different function in the immune system. Each can also give … Continued
Medically reviewed by Eric Jacobsen, MD One symptom of lymphoma can be the development of lumps under the skin, usually in the neck, armpit, or groin. The lumps have a rubbery feel and are usually painless. Not all such lumps are a sign of lymphoma, but when they occur at these sites, it’s advisable to … Continued
A troublesome cough led Patty Reid on a nine-months-long medical odyssey that resulted in a diagnosis of non-Hodgkin lymphoma (NHL). Just as the then-60-year-old was preparing for a stem cell transplant in late 2016, a new research discovery prompted her doctors to change the type of transplant Reid received—greatly lessening her risk for another cancer … Continued
There was a time when Georgette Hannoush couldn’t imagine a bright future. In a four-year span, the mother of four—including triplets—was diagnosed with two different types of cancer. But because of her team at Dana-Farber Cancer Institute, Hannoush has been in remission for more than three years—and she credits her faith and the people she … Continued
No athlete welcomes an injury, but a simple scratch may have saved Rich Oakley’s life. Oakley was diagnosed with cancer in 2003, as a high school senior, after a scratch from a sports injury led to a swollen neck. When the swelling didn’t subside, Oakley’s mother brought him to the doctor for tests, which revealed … Continued
Sandi and George Schussel first met on an airplane, beginning a 55-year journey that has taken them across the world, over oceans, into the mountains, and down countless paths. When Sandi learned she had a rare blood cancer known as angioimmunoblastic T-cell lymphoma (AITL), the couple saw her diagnosis as another trail to travel. This … Continued
In early 2018, Sandra Linberg received an infusion of CAR T cells only a few months after the therapy was approved for treating her type of cancer. After only a month, her lymphoma had completely disappeared – she was in a complete remission. “Those little warrior cells took care of it,” declared Linberg, who has continued … Continued
Cutaneous lymphoma is a rare subtype of non-Hodgkin lymphoma that starts in the skin.
CAR T-cell therapy uses specially altered T cells — which are part of the body’s immune system — to fight cancer.
During a “couples chemo” session, Kevin got down on one knee and popped the question to Tim, his partner of 37 years. They tied the knot in the Healing Garden at Dana-Farber.
Are massages harmful for someone undergoing cancer treatment? Is it really possible they could spread lymphoma? The simple answer: No.
The word “refractory” in general use means stubborn or intractable, and in medicine it is specifically applied to disease that does not respond to treatment. Refractory cancer refers to cancer that may be resistant at the beginning of treatment, or becomes resistant during treatment. “We would consider disease refractory if doesn’t respond at all or … Continued
One of the most exciting new cancer treatments, CAR T-cell therapy takes its complicated name, in part, from a fire-breathing monster in an ancient Greek myth. CAR is an acronym for “chimeric antigen receptor,” referring to genetically engineered molecules manufactured in a laboratory, inserted into the genetic material of immune T cells that have been … Continued