Artificial Intelligence (AI) has tremendous potential to advance healthcare and improve the lives of everyone. But successful clinical translation requires evaluating the performance of AI models on large and diverse real-world datasets. MLCommons, an open global engineering consortium dedicated to making machine learning better for everyone, announced on July 17, 2023, a major milestone toward … Read more
Pancreatic cancer often eludes early detection because symptoms typically don’t surface until the disease is well established. This makes it important to respond appropriately to warning signs, even though some may be vague or caused by another health condition. What are the symptoms of pancreatic cancer? Most symptoms of pancreatic cancer are caused when tumors … Read more
Although hemorrhoids and colon cancer share certain symptoms, such as rectal bleeding, they are very different conditions. People who experience symptoms of either should get evaluated by a physician: while hemorrhoids are far more common than colon cancer, an exam is necessary to determine which one, if either, a patient has and how it should … Read more
By Valerie Frank Ever since I can remember, I’ve made people laugh. I was always the funny friend, and when I was in my mid-20s I made it official by becoming a Main Stage cast member of ImprovBoston — an improvisational comedy theater in Cambridge, MA. Once I retired from improv to become a suburban … Read more
Set to begin radiation therapy the next day, the patient was anxious. Not just about her thoracic cancer treatment, but also about the oral chemotherapy she took at home. It came with high insurance copays. Then came a phone call that eased her concerns. As they had earlier in her treatment, members of Dana-Farber’s Specialty … Read more
For nearly a century, scientists have appreciated that cancer cells rely on a process called glycolysis to grow and divide at very high rates. In the process, the cells avidly break down glucose to produce lactate, which has been considered a passive by-product — a mechanism known as the Warburg Effect, named after the German … Read more
A novel hematopoietic stem cell transplantation (HSCT) method utilizing ‘graft sculpting’ is being tested in a phase 1 clinical trial in patients with refractory acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) who are at the highest risk of relapse after ‘standard’ transplants. In fact, the patients in the trial don’t qualify for a standard … Read more
Waldenström’s macroglobulinemia (WM) is a blood cancer that is extremely rare, affecting around 1500 people in the US each year. About 20 percent of those cases are considered familial, meaning that many members of the same family also have some form of blood cancer, such as myeloma or lymphoma. An even smaller group — five … Read more
When Jennifer Fullerton was diagnosed with breast cancer at age 29, her mind immediately went to the worst-case scenario. “I thought I was going to die. That first day all I could think was ‘why me,’” Fullerton says. “My mom very poignantly told me, ‘Today you can say ‘why me,’ but tomorrow, ‘why not me’. And you … Read more
Brian Humberd firmly believes in an attitude of gratitude. The biotech recruiter from Melrose, Massachusetts remains eternally grateful to Dana-Farber medical oncologist David Fisher, MD, who not only recommended a life-saving stem cell transplant to treat his central nervous system (CNS) lymphoma, but whose advice enabled Humberd to become a father after his cancer treatments. … Read more
By Howard Brown As the Adult Stem Cell Transplant Program at Dana-Farber celebrates its 50th anniversary, one cancer survivor whose 1990 transplant came when the procedure was far more arduous — and far less successful — reflects on his experience. I have a four-by-three-inch plastic bag that I’ve saved for more than 32 years. It’s … Read more
When Mary Richichi flew from Boston to Utah this summer to attend her grandson’s wedding, she made sure to pack her dancing shoes. The 79-year-old was celebrating not only the happy couple’s big day, but the fact she was there to witness it, thanks to the Dana-Farber specialists who treated her breast cancer and are … Read more
When breast cancer spreads, or metastasizes, it’s more likely to travel to some parts of the body than others. The most common sites of metastasis include the bones, brain, liver, or lungs. It’s rare for patients with early-stage breast cancer, which has not spread beyond the breast or adjacent lymph nodes, to develop a brain metastasis: The … Read more
Finding a lump in the groin can be frightening, but it is rare for a lump under the skin to indicate cancer. Regardless, any changes in your body should be reported to a medical professional, who can help you determine the best course of action. Where exactly is the groin? The groin makes up the … Read more
If you have been vaccinated against COVID-19, the U.S. Centers for Disease Control and Prevention (CDC) recommends different numbers of vaccines depending on if you are immunocompromised. Immunocompromised people can include people who have: As of December 2022, the COVID-19 vaccination recommendation for immunocompromised people, including active cancer patients, includes: A booster dose is another dose given … Read more
Is it normal to have a lump in the armpit? A lump in the armpit is usually not something to worry about, and the explanation for it is usually something mild and relatively harmless. Will a lump in the armpit go away? When should I see a doctor? In many cases, lumps under the armpit … Read more
The first thing you should know is that most neck lumps are not a sign of cancer. There are a host of more common causes of neck lumps, including infections, cysts, boils, and other common skin irritations. However, a neck lump can also be an early sign of several types of cancer, so if your … Read more
Got an itch that just won’t go away? Also known as pruritus (proo-rai-tuhs), itchy skin can have a wide variety of causes, including seasonal allergies and dry skin; various skin conditions, such as eczema; and even certain detergents and lotions. The good news is that itchy skin is typically not a sign of cancer. This … Read more
The most common symptom of lymphoma is the development of lumps under the skin. The lumps themselves are swollen lymph nodes, and they typically appear in the neck, armpit, or groin. Not all such lumps are a sign of lymphoma. It is normal for lymph nodes to swell as they fill with white blood cells as part … Read more
Back pain can occur for a variety of reasons not related to cancer, such as injury or arthritis; in certain circumstances, back pain can be related to cancer.