Dana-Farber Patient Recovering Well After Cancer and the Coronavirus

Pam Dobay is a warrior. In the last three years, the 67-year-old has dealt with a cancer diagnosis and stem cell transplant before recently contracting the coronavirus. None of it was easy, but today, Dobay is recovering at home. She says she cannot begin to express the gratitude she feels towards everyone who has cared … Continued

Chimeric Antigen Receptor (CAR) T-Cell Therapy: What Does “Chimeric” Mean?

One of the most exciting new cancer treatments, CAR T-cell therapy takes its complicated name, in part, from a fire-breathing monster in an ancient Greek myth. CAR is an acronym for “chimeric antigen receptor,” referring to genetically engineered molecules manufactured in a laboratory, inserted into the genetic material of immune T cells that have been … Continued

Mastocytosis: What is It and How Is It Treated?

Mastocytosis is a rare type of mast cell disorder characterized by the abnormal accumulation of mast cells in various organ systems such as the skin, liver, spleen, intestine, or bone marrow. It is one of two major types of mast cell disorders; the other major, more common type is mast cell activation syndrome. To keep … Continued

POEMS Syndrome Patient Goes from Immobility to Recovery

The vow Chukwuma Anyanwu made to himself shortly after the birth of his third child in June 2015 speaks volumes, not only about the dire state of his health at the time but also about the mettle with which he is made. “My goal was to be able to walk before my son did,” the … Continued

Blood Relatives: Family Bound by Love and Rare Blood Disorder

Tracy Antonelli was four when she was diagnosed with thalassemia, a rare blood disorder that occurs often enough in Mediterranean countries like Italy that an old adage, uttered only partially in jest, warns Italian-Americans against marrying other Italian-Americans. In 2002, a grown-up Antonelli wed Patrick Mooty, whose background is mostly Irish. Their three daughters – … Continued

The Genomics Behind Blood Cancers and Other Blood Disorders

Many of the secrets of why precancerous conditions sometimes become cancerous are hidden in cells’ genes. At Dana-Farber, researchers are collecting tissue samples to see if they can pry open those secrets and unlock new treatment options for certain types of blood cancers and other blood disorders. They’re also exploring whether tumor DNA floating in … Continued

What is a Benign Blood Disorder?

It might sound counterintuitive, but not every patient comes to Dana-Farber for cancer treatment. For example, the Institute’s experts regularly see patients seeking help with benign (non-cancerous) blood disorders. Benign blood disorders such as anemia and sickle cell disease are often treated at cancer centers because such institutions are home to experts in hematology, which … Continued