Jeffrey Borges was used to hearing that doctors had few good treatments for his mastocytosis. He’d heard it when he was first diagnosed with the disease at age 16 and a course of antihistamines and ultraviolet light therapy had little effect on the rash that covered most of his body. He heard it in his … Read more
Pam Dobay is a warrior. In the last three years, the 67-year-old has dealt with a cancer diagnosis and stem cell transplant before recently contracting the coronavirus. None of it was easy, but today, Dobay is recovering at home. She says she cannot begin to express the gratitude she feels towards everyone who has cared … Read more
Bone marrow failure occurs when the bone marrow – the soft, spongy center of the bones – fails to produce enough healthy blood cells to keep up with the body’s needs.
One of the most exciting new cancer treatments, CAR T-cell therapy takes its complicated name, in part, from a fire-breathing monster in an ancient Greek myth. CAR is an acronym for “chimeric antigen receptor,” referring to genetically engineered molecules manufactured in a laboratory, inserted into the genetic material of immune T cells that have been … Read more
Mastocytosis is a rare type of mast cell disorder characterized by the abnormal accumulation of mast cells in various organ systems such as the skin, liver, spleen, intestine, or bone marrow. It is one of two major types of mast cell disorders; the other major, more common type is mast cell activation syndrome. To keep … Read more
The vow Chukwuma Anyanwu made to himself shortly after the birth of his third child in June 2015 speaks volumes, not only about the dire state of his health at the time but also about the mettle with which he is made. “My goal was to be able to walk before my son did,” the … Read more
Tracy Antonelli was four when she was diagnosed with thalassemia, a rare blood disorder that occurs often enough in Mediterranean countries like Italy that an old adage, uttered only partially in jest, warns Italian-Americans against marrying other Italian-Americans. In 2002, a grown-up Antonelli wed Patrick Mooty, whose background is mostly Irish. Their three daughters – … Read more
Many of the secrets of why precancerous conditions sometimes become cancerous are hidden in cells’ genes. At Dana-Farber, researchers are collecting tissue samples to see if they can pry open those secrets and unlock new treatment options for certain types of blood cancers and other blood disorders. They’re also exploring whether tumor DNA floating in … Read more
It might sound counterintuitive, but not every patient comes to Dana-Farber for cancer treatment. For example, the Institute’s experts regularly see patients seeking help with benign (non-cancerous) blood disorders. Benign blood disorders such as anemia and sickle cell disease are often treated at cancer centers because such institutions are home to experts in hematology, which … Read more