Anti-Microbial Drug Targets Key Driver of Chronic Lymphocytic Leukemia

Dana-Farber scientists have found that a generic anti-microbial drug can block a key molecular driver of chronic lymphocytic leukemia (CLL) cells, and when tested in a small clinical trial of advanced CLL patients who had relapsed, the drug slowed disease progression in half of them. The drug, pyrimethamine, achieved stable disease in eight of the … Read more

For Young Mom with Chronic Lymphocytic Leukemia, Clinical Trial is a Life-Saver

As head of marketing for a leading international news agency, Kelly Ives routinely worked with journalists across the globe. When it came to chronic lymphocytic leukemia (CLL), however, it was her own reporting skills that led Ives to a life-changing treatment. Ives was a 37-year-old mom with a career and three young children, including an … Read more

What is the Role of Genetics in Lymphoma and Chronic Lymphocytic Leukemia?

Studies in large populations have shown that people who have a near relative with a form of lymphoma or chronic lymphocytic leukemia (CLL) have an increased risk of developing these diseases themselves. Both lymphoma and CLL are relatively uncommon: the average person’s lifetime risk of developing CLL, for example, is 0.57%, according to the American … Read more

Patient with Cancer Shares Tips for Being Your Biggest Advocate

Life is like a Mad-Lib, and Jennifer White is taking control of what she can fill in the blank spaces. The Atlanta-based cyber security consultant was diagnosed with chronic lymphocytic leukemia (CLL) in January 2019. In July of that same year, White, a Boston native, came to Dana-Farber. She currently comes to Boston four times … Read more

What Are the Differences Between Lymphocytic and Myelogenous Leukemia?

Medically reviewed by Martha Wadleigh, MD Leukemia arises from malfunctions in stem cells within the bone marrow that cause abnormal white blood cells to flood into the bloodstream. Leukemias are classified as either myelogenous (also called myeloid) or lymphocytic, depending on which types of white blood cells are affected. What is the difference between these types … Read more

New Options for First-Line Treatment of Chronic Lymphocytic Leukemia

Medically reviewed by Jennifer Brown, MD Most patients with chronic lymphocytic leukemia (CLL) now have several options for first-line therapy, thanks to new clinical trial results and novel targeted agents. Many patients with CLL, a slowly progressive blood cancer in which the bone marrow makes too many white blood cells, don’t need immediate treatment but … Read more