Hodgkin Lymphoma: The Latest in Treatment and Research

Chemotherapy has been the backbone of treatment for both untreated and relapsed/refractory (R/R) classic Hodgkin lymphoma (cHL). But treatment paradigms for cHL are changing. Immunotherapies that unmask cancer cells and make them vulnerable to our immune system, called immune checkpoint inhibitors (ICIs), were recently approved for relapsed and refractory cHL. Examples include PD-1 inhibitors such … Read more

Understanding Your Pathology Report

If you have had a biopsy or surgery that removes tissue from your body, in almost all cases a sample will be sent to a pathology lab for examination. Pathologists, who specialize in looking at microscopic tissue samples, will look for signs of disease.  Their findings will be detailed in a pathology report. The first … Read more

Immunotherapy for Cancer: What it Is, How it Works, and Where it’s Going

Immunotherapy refers to treatments that use the body’s immune system to combat diseases. Immuno-oncology focuses on efforts to use the immune system as a weapon against cancer.  The immune system is a collection of organs, tissues, specialized cells, and substances that protect the body against infection and disease. While the immune system can often handle very small … Read more

What is Clonal Cytopenia of Undetermined Significance (CCUS)?

CCUS is a condition in which a person has a low blood count — a low level of certain kinds of blood cells — without an apparent cause, and a portion of the blood cells carry an acquired genetic mutation. The condition, which is usually diagnosed after a routine blood test followed by specialized molecular … Read more

What Is Triple-Negative Breast Cancer?

Triple-negative breast cancer is a subtype of breast cancer where cancer cells do not contain estrogen receptors or progesterone receptors, and HER2 receptors are also absent or present at low levels. Triple-negative breast cancer accounts for roughly 15% of all breast cancer cases and can be somewhat more aggressive than hormone-positive or HER2-positive breast cancer.  Who is most at risk for … Read more

What Is HER2-Positive Breast Cancer?

HER2-positive breast cancer is a subtype of breast cancer. Approximately 20% of breast cancer cases are HER2-positive.   HER2, which stands for human epidermal growth factor receptor 2, is a protein that appears on healthy breast cells in low numbers and is vital for the normal growth of breast cells. HER2-positive cancers have higher than normal levels of … Read more