What Are Aromatase Inhibitors?

Breast cancer cells
Breast cancer cells

Aromatase inhibitors are drugs given to patients with hormone-receptor-positive breast cancer (HR+). They target the aromatase enzyme, which helps produce female hormones such as estrogen.

Estrogen drives the growth of many HR+ tumors, and these drugs help control estrogen production, says Harold Burstein, MD, PhD, a breast cancer specialist in the Susan F. Smith Center for Women’s Cancers at Dana-Farber.

Aromatase inhibitors can help prevent breast cancer recurrence and help control advanced cases of breast cancer in postmenopausal women, he adds.

Learn more about aromatase inhibitors in the video below.