It was a hot day on the links in New Hampshire in July 2014. Carol MacKenzie recalls that her neck was strangely sore. By the end of the round of golf, she had a fever. Soon after, MacKenzie met with an oncologist. In 1996, she had been diagnosed with early-stage triple-negative breast cancer and successfully treated. Eighteen years later, … Read more
After her breast cancer surgery, Tia struggled with mobility in her left shoulder. It felt as though the joint was frozen, and she could feel some swelling in her chest. After several dead ends, she learned that this feeling may be caused by early-stage lymphedema. This condition is a common side effect of breast cancer … Read more
Kirsten Dahl knows plenty about targets, so when she was diagnosed with an aggressive form of HER2+ breast cancer, she devised her own unique brand of targeted cancer therapy. In addition to heeding the advice of her medical team, Dahl focused on the one thing she most missed to help her get through nearly two … Read more
The American Cancer Society 2025 Facts and Figures report contained alarming information about cancer rates in young women. Women under 50 are getting cancer more frequently than men of the same age. In 2022, for every young man who got cancer, about 1.5 young women did. Now that number is closer to 1.8. The cause … Read more
Just like genetic and lifestyle factors, the composition of breasts can affect a person’s risk of developing breast cancer in their lifetime. Although it’s not yet known why, people with dense breasts have a higher risk for breast cancer. Breast density is a measure of how much glandular and fibrous tissue there is in the … Read more
Between 2000 and 2021, breast cancer rates in people under 50 of Asian or Pacific Islander decent rose by nearly 50%, from 36 to 55 cases per 100,000, with sharper increases between 2020 and 2021. Rates of breast cancer in young people are known to be rising in general, but this rate increase, according to … Read more
As we age, we may turn down the volume on our music and dial down the number of late nights, but deep inside our bodies, expression levels of a gene called midkine are ratcheting upward. This uptick appears to have impact on our health. New work from the Dana-Farber lab of breast cancer researcher Kornelia … Read more
When breast cancer metastasizes, it often heads for the brain, where it can be exceptionally difficult to root out. The key to preventing the spread of the cancer, or thwarting it if it does reach the brain, is to understand the mechanism that turns stationary tumor cells into nomadic intruders. In a recent study, a … Read more
Overall survival of breast cancer has improved for everyone in the U.S. in recent years, but the pace isn’t the same for all groups of people. Some groups still experience dramatic disparities. For example, according to the American Cancer Society: Dana-Farber wants to close these gaps so that everyone benefits equally from high-quality care and … Read more
When Sandra Noack returned home from a visit to Bogota, Colombia, to visit her family, there was a letter waiting for her. It was a leaflet sent via the Massachusetts Department of Public Health describing a clinical trial at Dana-Farber Cancer Institute for Latina and Hispanic breast cancer survivors. The trial didn’t involve any medicine. … Read more
When Meghan MacDonald visited her primary care provider in the fall of 2022 to get a lump in her breast examined, they confirmed her suspicion that it was just an inflamed cyst. Relieved, MacDonald began a course of antibiotics, but when the lump didn’t go away, her doctor ordered a mammogram, and when the results … Read more
Over the past 30 years, outcomes have improved dramatically for women with breast cancer. There are many new treatments, including hormone therapies and CDK4/6 inhibitors. In contrast, there has been no improvement in the outcomes for men with breast cancer. And current guidelines don’t support the use of newer therapies in men. “If we do … Read more
In a small percentage of women, a painful breast lump turns out to be cancer.
“Overall, contraceptives still have a favorable risk benefit for women as contraception,” says Wendy Chen, MD, a senior physician in Dana-Farber’s Susan F. Smith Center for Women’s Cancers.
Harmful BRCA mutations are uncommon in the general population. About one in every 500 women in the United States has either a BRCA1 or BRCA2 gene mutation.
Could adding soy milk to your coffee or substituting tofu for meat increase your risk of breast cancer? The research is conflicting, but our breast cancer doctor, Wendy Chen, MD, MPH, is here to help us cut through the noise. “[It’s] one of the most common questions I get from breast cancer survivors,” says Chen, … Read more
Receiving the news that something abnormal has turned up on a routine mammogram can be frightening, but breast calcifications are usually harmless. In rare instances, they can be an early sign of breast cancer, though calcifications themselves do not develop into cancer. What are breast calcifications? All cells in the body have a life span; … Read more
Sitting recently in Dana-Farber’s Healing Garden, Kireina Bell Sancho focuses on her task. She slowly works navy blue yarn through her needles, drawing the yarn back and forth to form the base of a headband – a gift for her sister. She says the repetitive motion, which requires both attention and precision, has been stress-relieving during … Read more
Gabby Spear, a young, active mom, had never noticed a lump or pain before suddenly finding her breast cancer in November 2013, when she was 38. She was shocked. But, with two young daughters, there wasn’t much time to adjust to her new normal. In the latest episode of Voices: Then and Now, Spear recalls her … Read more
Charlotte Kelly hated having her chemotherapy port accessed, but her mother, Patrice, found a way to calm the toddler. Each time tears came, Patrice would rub her nose against Charlotte’s – and the pair would get past their fears together. Today the ritual continues, even though Charlotte’s last neuroblastoma checkup at Dana-Farber/Boston Children’s Cancer and … Read more