Why is Pancreatic Cancer So Difficult to Treat?

Pancreatic cancer is seldom detected early enough for curative treatment to be performed – and even if it were, it would still be very difficult to vanquish. The pancreas, a narrow, six-inch-long gland that makes digestive juices and hormones such as insulin, is tucked away deep inside the body behind the stomach, small intestine, liver, … Read more

Attacking A Weak Point in Pancreatic Cancer’s Defense

In the fall of 2015, at the age of 44 – young for a person to be diagnosed with pancreatic cancer – Doron Broman was stunned to learn he had a large tumor on his pancreas that had metastasized to the liver. Facing only months to live, Broman would find himself in the right place … Read more

Can Immunotherapy Help Patients with Pancreatic Cancer?

Patients with pancreatic cancer often ask Dana-Farber’s Brian Wolpin, MD, MPH, about immunotherapy, the rising star of cancer treatment that’s making impressive gains against many types of malignancies. Immunotherapy drugs, which mobilize the patient’s immune defenses to recognize and attack tumor cells, have worked against lethal cancers such as melanoma and some lung cancers – … Read more

Whipple Operation: What It Is, Side Effects, Follow-Up

What is the Whipple operation/procedure? Many pancreatic cancer patients are diagnosed after the cancer has spread beyond the pancreas, making surgery a risky treatment option. But for those patients whose cancer is localized, surgery may be used to remove the tumor and prevent further spread. When the tumor is confined to the head or neck of the pancreas, … Read more

Researchers Focusing on Early Detection, Immunotherapy for Pancreatic Cancer

The challenge with pancreatic cancer has always been to catch it early. Because of its subtle, variable symptoms, the disease often isn’t diagnosed until an advanced stage, when it is particularly difficult to treat. Researchers are investigating not only how to detect the disease earlier but also how to better understand its causes and develop … Read more

A Teen’s Journey: Developing a Diagnostic Test for Pancreatic Cancer

This post was originally written and published on Vector, Boston Children’s Hospital’s science and clinical innovation blog.  At age 13, Jack Andraka lost a family friend to pancreatic cancer. At age 15, he developed a diagnostic test for pancreatic cancer that early findings suggest is highly accurate. In this session from Boston Children’s Hospital’s Global Pediatric … Read more