Why Do Scientists Use Zebrafish to Study Cancer?

Cancer scientists use a wide variety of techniques to study the growth and development of tumor cells. Laboratory research often focuses on individual cells or tissue samples, but to learn how cancers grow and respond to therapies in living organisms, scientists rely on other experimental models. In recent years, zebrafish have become the model of choice for studying many cancer types. Dana-Farber’s A. Thomas Look, MD, who uses zebrafish in his own work, explains why.

The HIV Spike, Revealed

The gaudy green image you see below is not an avant-garde sculpture, but the most detailed image yet made of the protein “spike” that allows HIV – the virus that causes AIDS – to latch onto and enter human blood cells.

Fun with Pink

It was glitter and glue when patients, visitors, and Dana-Farber staff gathered on Oct. 4 to create art on an unusual canvas – bras. Hosted by Friends’ Place and Dana-Farber’s Creative Arts Program, the “Decorate a Brassiere” art therapy event allowed attendees to creatively honor Breast Cancer Awareness Month.

The Faces of Pediatric Cancer – Sarah Levin

Faces of Childhood Cancer: Sarah Levin Sarah Levin is 11 years old, and has beaten acute lymphoblastic leukemia (ALL) twice. This is her story. The first time I got diagnosed with ALL I was only three, so I don’t remember that much about it. But what my mom and dad have told me is that it was a really sad and scary time for my family.

The Faces of Pediatric Cancer – Fernando Morales

Fernando Morales is a student athlete. Last year he was sidelined from the life he knew after he was diagnosed with Ewing sarcoma. Now done with treatment Fernando is back with his teammates, sporting a positive outlook and a new appreciation for life. This is his story.  As a soccer player and member of the track and field team at my high school, running is a big part of my life. But one morning I started getting shooting pains in my knee. All of a sudden walking and running became very difficult. In the blink of an eye I lost …

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The Faces of Pediatric Cancer – Caitlynne McGaff

Caitlynne McGaff is an active 17-year-old. She owes a lot of her mobility to an innovative surgery she had at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center to treat her osteosarcoma. This is her story. When most people my age talk about a day they’ll never forget, they mention getting their license, or a great sweet sixteen party. For me, it’s a little different.

A Closer Look at Childhood Cancer

September is National Childhood Cancer Awareness Month. Beginning next Wednesday, and over the next four weeks, we’ll introduce four children – Caitlynne, Fernando, Sarah and Steven – who while still young, have already overcome one of the biggest challenges of their lives. These four represent just a few of the many faces of childhood cancer across the United States and the world. We hope you’ll join us in September in honoring all of the children who come to Dana-Farber/Children’s Hospital Cancer Center, as well as their caregivers—doctors, nurses, psychologists, social workers, researchers, administrators and more—who work tirelessly until every child is …

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Black Hawk Pilot Ben Groen battles lymphoma diagnosis

New Year’s Eve 2010. In a military hospital in Hawaii with much of the staff away for the holidays, Army pilot Ben Groen learned he’d been diagnosed with T cell lymphoblastic non-Hodgkin lymphoma, a rare, aggressive cancer of the white blood cells and lymph nodes. His doctor told him that his treatment – which would need to begin almost immediately and require months of hospitalization – would exceed the capacity of the base’s blood bank.

Can aspirin prevent or treat cancer?

Aspirin has been around for over 100 years. In the last 50 years, research has shown that regular use of aspirin may prevent heart disease. Now a new study points to aspirin’s effectiveness in preventing and treating cancer. A recent University of Oxford investigation pooled more than 50 studies to show that regular aspirin use could reduce your chances of developing certain types of cancer, and may be effective in treating some cancers as well. We talked to Charles S. Fuchs, MD, MPH, director of the Gastrointestinal Cancer Center at Dana-Farber for his take on the recent research.

How to protect children from the sun

Applying sunscreen to wiggly young children can be a challenge, but sun protection is especially critical for young skin. Babies and young children are especially sensitive to the sun. There are several lines of evidence indicating that burns during youth significantly contribute to melanoma risk. For instance, just one blistering sunburn in childhood more than doubles an individual’s risk of developing melanoma later in life. In a three-year study of fifth graders, the percentage of children who “often or always” used sunscreen declined from 50 to 25 percent.