I Have Metastatic Breast Cancer: What Is My Prognosis?

A metastatic breast cancer diagnosis can be a stressful, life-changing event. While metastatic breast cancer it is not curable, it is treatable. Today, with the help of new treatments including biologic targeted therapies and novel drug combinations, many patients with metastatic disease can live well for years.  Metastatic breast cancer means that the cancer has … Read more

Coping with Breast Cancer as a Young Adult

Young women with breast cancer face many unique emotional challenges: They may be in college, dating, starting a career, raising a family, or trying to start one. “Cancer disrupts many aspects of young adulthood such as family planning, careers, relationships, sexuality, and sexual health,” said Karen Fasciano, PsyD, clinical psychologist and director of Dana-Farber’s Young … Read more

Can Women Get More Than One Lumpectomy?

For many women with localized breast cancer, a lumpectomy followed by breast radiation therapy may be the most effective treatment, with survival rates equal to a mastectomy. But if the cancer comes back, can women have additional lumpectomies? Women should not have a second lumpectomy in the same breast if they were previously treated with … Read more

New Study: Chemo Before Surgery Avoids Need for Mastectomy for Many with Triple-Negative Breast Cancer

Chemotherapy before surgery shrank triple-negative breast tumors in women in a clinical trial to the point where half of those who had not been eligible for breast-conserving surgery became eligible for it, according to investigators at Dana-Farber and Brigham and Women’s Hospital. The findings were reported at the American Surgical Association annual meeting and in … Read more

Forty Years After Introduction, Breast Cancer Prevention Drug Still Effective

Nearly 40 years after its introduction, tamoxifen continues to prove its value as a breast cancer prevention drug. The most recent evidence comes from the International Breast Cancer Prevention Study 1 (IBIS-1), which for 20 years has been tracking breast cancer occurrence and survival rates in more than 7,000 women who had a higher than average … Read more

FDA Approves New Therapy for Metastatic Breast Cancer

The U.S. Food and Drug Administration has approved a new treatment  for women with advanced (metastatic) breast cancer. The new therapy, palbociclib, will be used to treat postmenopausal women with metastatic estrogen receptor-positive (ER-positive) breast cancer who have not received previous treatment. Palbociclib, which is marketed under the name Ibrance, will be used in combination … Read more

20 Years After BRCA: What We’ve Learned About Genetics and Breast Cancer

Twenty years ago, scientists announced the discovery of BRCA1, which arguably has become the best-known cancer susceptibility gene in the world. When inherited in a mutated form, the gene sharply increases a woman’s chances of developing breast or ovarian cancer, often at an early age. The discovery has changed the way women with a family … Read more