Breast cancer may develop in one part of the body, but it’s not just one disease. In fact, oncologists think of breast cancer as at least three different types of diseases.
Erica Mayer, MD, MPH
Triple-negative breast cancer (TNBC) describes breast cancer cells that do not have estrogen, progesterone, or HER2 receptors. It makes up approximately 15 percent of all breast cancers and is typically more aggressive than the other two types, estrogen receptor-positive breast cancer and HER2-positive breast cancer.
“It may be the smallest group, but TNBC still represents thousands of women with breast cancer, so it is a very important group for us,” says Erica Mayer, MD, MPH, a medical oncologist at Dana-Farber’s Susan F. Smith Center for Women’s Cancers.
A preventive (or prophylactic) mastectomy is the removal of a healthy breast to reduce the chances of developing breast cancer in that breast. A patient might consider a preventive mastectomy under different circumstances, including: There are many things to consider before deciding. Mastectomy is major surgery, so it is important to understand the risks and … Read more
Women who believe that drinking moderate amounts of alcohol won’t increase their risk of breast cancer may want to think again.
Last year, Wendy Chen, MD, of the Susan F. Smith Center for Women’s Cancers at Dana-Farber and her colleagues published a study showing that women who drank as little as three to six glasses of wine or other alcoholic beverages a week increased their breast cancer risk by about 15 percent.
When I learned I had a stage 4 breast cancer, I decided not let it rob me of the opportunities to enjoy my life. I still have a physically active, socially engaged lifestyle, and if you have metastatic breast cancer, so can you.
Breast cancer is the most common type of cancer in women, but men can also be diagnosed with the disease. How common is breast cancer in men? While male breast cancer is rare, according to the National Cancer Institute about 2,000 men will receive this diagnosis every year, or less than 1% of all new … Read more
When Jane Davis was diagnosed with breast cancer last July, she began learning as much as she could about her disease. Davis quickly discovered one of the most startling statistics about breast cancer: Up to 40 percent of women who have a lumpectomy require a second surgery. That’s because surgeons often cannot microscopically remove the entire tumor.
But Mehra Golshan, MD, FACS, director of Breast Surgical Services at Dana-Farber/Brigham and Women’s Cancer Center, is trying to change that with a phase I breast surgery pilot study. It’s the first of its kind in the world.
While there are genetic and lifestyle risks for breast cancer, some may not realize that breast density also plays a significant role in risk for the disease. Breasts are considered dense if they are mostly made up of glandular and fibrous tissue and not much fat. Breast density can be seen only on a mammogram; the firmness of breasts is … Read more
There has been remarkable recent progress in identifying effective treatments for patients with metastatic breast cancer – that is, cancer that has spread beyond the breast and underarm lymph nodes to other parts of the body.
I have been a metastatic breast cancer patient at Dana-Farber for over four years now. I have an amazing team of providers, especially my oncologist Ann Partridge, MD, MPH, and nurse practitioner Anne Kelly, MSN, NP.
Aromatase inhibitors (AIs), such as Arimidex, Aromasin, and Femara, have proven to be more effective than previous hormonal treatments for treating both early and advanced breast cancer in post-menopausal women whose tumors are dependent on estrogen. Compared with tamoxifen, these drugs are less likely to cause blood clots or raise the risk of endometrial cancer. As a result, AIs are used both in patients with early breast cancer and in those with metastatic disease.
It was glitter and glue when patients, visitors, and Dana-Farber staff gathered on Oct. 4 to create art on an unusual canvas – bras. Hosted by Friends’ Place and Dana-Farber’s Creative Arts Program, the “Decorate a Brassiere” art therapy event allowed attendees to creatively honor Breast Cancer Awareness Month.
By Filipa Lynce, MD Inflammatory breast cancer is a rare but aggressive form of breast cancer that affects young women more than older women. Because it’s relatively uncommon — it represents less than five percent of all breast cancer cases — people are often confused about what inflammatory breast cancer is and how you can … Read more
Rebecca Byrne had waited years for a doctor to tell her, “You’re pregnant.” She never imagined that just a few months after she first heard those words, she would hear four more: “You have breast cancer.”
Byrne still tears up when telling the story, but smiles when her 20-month-old daughter, Emelia, leaps into her lap. Emelia is the happy outcome of a painful period of Byrne’s life, when the joys of pending and early motherhood were shadowed by chemotherapy treatments, hair loss, radiation, and uncertainty.
For many women who enjoy a glass of wine, research showing that relatively small amounts of alcohol can raise their risk of breast cancer are disconcerting, to say the least. And confusing, too.
How much drinking is OK? Isn’t a glass of red wine a day good for your heart — and couldn’t that be more important?
In the past five or 10 years, knowledge about alcohol and breast cancer has been changing as studies produce new results and are publicized, sometimes over-dramatically, in the media. At the same time, there’s growing evidence that moderate drinking can be healthy for the heart.
Many people who discover a breast lump confide in a friend or family member before talking to their doctor. They may be told that if a breast lump hurts or is sore, it probably isn’t cancer. To find out whether this urban legend holds any truth, we checked with Beth Overmoyer, MD, FACP, of Dana-Farber’s … Read more
Harold J. Burstein, MD, PhD, a Dana-Farber breast cancer specialist, discusses some of the important studies presented at the 2011 CTRC-AACR San Antonio Breast Cancer Symposium. The five-day meeting includes more than 1,000 scientific presentations, seminars, and posters, with a focus on emerging treatments in hard-to-treat populations, patients with metastatic breast cancer, and breast cancer … Read more
Ann Partridge, MD, MPH, was instrumental in the founding of Dana-Farber’s Program for Young Women with Breast Cancer, part of the Susan F. Smith Center for Women’s Cancers. The program, which focuses on the unique needs of breast cancer patients under 40, helps patients access fertility, genetic screening, and counseling services. Dr. Partridge was recently … Read more