Like many people, Karen Lagasse has never been a big fan of the dentist. But she’ll always be thankful for a 2013 tooth extraction for paving the way to a life-saving discovery. Noticing Lagasse’s elevated blood pressure, her dentist asked when she had last visited the doctor. Lagasse admitted it had been a few years, … Read more
Roberta “Bert” Green is a woman with a full and busy life. When not driving across the country with her husband, Ralph, in their RV, she alternates between paddle boarding, walking, e-biking, and skiing with the changing seasons around her rural Vermont home. Retired after a long career as a school neuropsychologist, she also makes … Read more
Ovarian cancer is a complex disease. Cell types, stages, and genetics play an important role for patients and their doctors as they decide which direction to take. Fortunately, patients today have many treatment options and new advances on the horizon. Physician-scientists at the Susan F. Smith Center for Women’s Cancers are leading the way in … Read more
For endometrial cancer, as for virtually every form of cancer, advances in genomics are transforming the understanding and treatment of this disease, which arises in the lining of the uterus or womb. As part of the Profile research project at Dana-Farber, Brigham and Women’s Hospital, and Boston Children’s Hospital, investigators have scanned hundreds of endometrial … Read more
PARP inhibitors are a targeted therapy used to treat certain cancers, including breast, ovarian, pancreatic, and prostate cancer, particularly in patients with BRCA1/2 mutations or other mutations that affect DNA repair systems in cells. They block proteins called PARPs (or Poly (ADP-ribose) polymerases) that play an important role in the life of a cell. When … Read more
As researchers and clinicians in the Susan F. Smith Center for Women’s Cancers at Dana-Farber continue studying the benefits of a two-drug combination in slowing progression of recurrent ovarian cancer, one patient is as a beacon of hope for her caregivers – and for others facing the disease. Betsy Brauser, treated with standard chemotherapy near … Read more
Traditionally, the war on cancer has been waged from the outside in, with therapies such as surgery, radiation, and drugs entering the body from external sources. For more than 100 years, however, a notion has persisted that the most formidable tool against cancer may come from within: the immune system. The immune system is the … Read more
Kerri Antonuccio marked her 40th birthday this spring with a fresh lease on life. For the first time since 2012, she didn’t feel too sick from cancer treatment to enjoy her big day. She was also able to travel to Mexico and serve as matron of honor at her sister’s wedding in May, as well … Read more
Understanding the risk factors for cancer can help you make decisions about prevention and screening for early signs of cancer. Here is a look at the five most common cancers in women*, as well as steps you can take to help find these diseases early if needed. 1. Breast cancer As with most cancers, the … Read more
Lynch syndrome — also known as hereditary non-polyposis colorectal cancer — is the most common hereditary form of colorectal cancer. In the United States, about 150,000 new cases of colorectal cancer are diagnosed each year and approximately 3 to 5% of these cancers are caused by Lynch syndrome. It’s estimated that 1 in 300 people may be … Read more
Fertility is a common concern among newly diagnosed cancer patients. For women with gynecologic cancer, the ability to have children depends on the type of cancer a woman has and the stage at which it is diagnosed, says Colleen Feltmate, MD, director of Minimally Invasive Surgery in Gynecologic Oncology at Dana-Farber/Brigham and Women’s Cancer Center. … Read more
Here’s a closer look at five things to know about risk of breast cancer and gynecologic cancers, including cervical, endometrial, and ovarian cancers. African American women are most likely to be diagnosed with breast cancer at a younger age. Breast cancer usually occurs in women over age 55, but young women can also develop the … Read more
Many associate cancer treatment with chemotherapy and radiation therapy, but for many women with gynecologic cancers, surgery is often the first line of defense. Colleen Feltmate, MD, director of minimally invasive surgery in gynecologic oncology at Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC), shares insight into surgical options to treat these cancers. Minimally Invasive vs. Open … Read more
Close to 100,000 women are diagnosed with a gynecologic cancer in the United States each year. In recognition of Gynecologic Cancer Awareness Month, we’re taking a look at the main types of gynecologic cancers and their symptoms. Cervical cancer In cervical cancer, cancer cells form in the tissues of the cervix, the lower, narrow end … Read more