Research in Advanced Ovarian Cancer Shows Promise

By Ursula Matulonis, MD After a long period of slow progress, new knowledge about the genetics of ovarian cancer is leading to the development and testing of new therapies. Researchers at the Susan F. Smith Center for Women’s Cancers will soon be launching several phase 3 clinical trials testing drugs known as PARP inhibitors for patients with platinum-sensitive recurrent ovarian cancer – tumors that initially responded to platinum-based chemotherapy agents but have shown evidence of regrowth at least six months after treatment. Phase 3 trials test drugs in large numbers of patients to evaluate the drugs’ effectiveness as well as …

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Outsmart Your Genes: Understanding BRCA1/2 Cancer Risk

When Angelina Jolie underwent a preventative double mastectomy earlier this year, this issue of cancer risk and genetics made front-page headlines. Jolie, who announced the operation in a New York Times op-ed, tested positive for the BRCA1 gene mutation and learned she had an 87 percent risk of developing breast cancer. Jolie’s announcement left many women wanting to know more: What is a gene mutation? Should I undergo genetic testing? What should I do if my tests are positive?

Exercise Can Help Fight Cancer Fatigue

By Nancy Campbell, MS Cancer-related fatigue is one of the most common complaints among cancer patients and survivors. This type of weariness, which typically occurs during treatment or in the first year after, is particularly difficult because it can last for long periods of time and doesn’t go away after sleep or rest. A growing body of research shows that cancer patients who get regular exercise report feeling less tired. If you’re interested in starting an exercise routine to address fatigue, consider these tips:

Living with Stage IV Ovarian Cancer

By Maura Perkins I can’t pinpoint when I started to get ovarian cancer symptoms. It was all very subtle and gradual. I was a healthy person. I ran, biked swam, hiked, and went to the gym regularly. A slight pain in my left side, difficulty digesting food, feeling of fullness, and shortness of breath: those were the subtle constellation of symptoms that landed me in my primary care doctor’s office. At the age of 50, I felt like I was going downhill fast.

What Should I Expect for my PET/CT Scan?

By Melanie Graham Patients undergo different types of scanning procedures to produce detailed images of potential cancer growth. Depending on the cancer, physicians may use MRI, mammography, CT, PET/CT or other technologies. While some of these procedures use only x-rays or radio waves to create images, a PET/CT scan uses a combination of traditional x-rays and computer imaging. A radioactive substance similar to glucose is given to the patient, and because cancer cells tend to use more glucose than normal cells, PET/CT scans can help detect the biological activity of those cancer cells.

‘You Have Us’: DF/BWCC Ad Campaign Launches

What is different and special about Dana-Farber/Brigham and Women’s Cancer Center? Several doctors and nurses answer this question in a new advertising campaign. The campaign promotes the specialized care and team approach provided in Boston and at regional care centers in South Weymouth and Milford, Mass. Behind DF/BWCC patient care is a team that collaborates with one another and accompanies patients through their cancer journey, the ads show. The campaign consists of three television ads as well as radio and print advertising. The theme of “You have us” carries through all media, encouraging viewers to “Take the first step together” with …

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Swim Across America Events Help Fund Research for Young Cancer Survivors

By Melanie Graham During a child’s cancer therapy and recovery process, insomnia can often be viewed as only a side effect in the scope of treatment-related symptoms. However, there are many physical and psychological implications that develop when a child does not sleep well, says Eric Zhou, PhD, a clinical psychology fellow in Dana-Farber’s David B. Perini, Jr. Quality of Life Clinic. Zhou, who is also a research fellow at Harvard Medical School, has spent the last year studying treatments for insomnia in adolescent and young adult cancer survivors through Dana-Farber’s Swim Across America Fellowship.