In Survivorship, Patricia Smith Looks to Help Others 

Patricia Smith’s experience with cancer will stay with her for the rest of her life. “Walking through deep waters changes you,” she says. “You’re still the same person, but you’re different.”   In 2009, Smith was diagnosed with B-cell diffuse lymphoma after she experienced weeks of fatigue and found a lump under her right arm. She … Read more

Science Behind Targeted Drug for Pediatric Brain Cancer Has Dana-Farber Roots 

Dana-Farber researcher Charles Stiles, PhD, remembers the call. It was 2008 and a colleague phoned from a conference to deliver the news. Two separate research teams had discovered a genetic driver for the most common of childhood brain tumors called pediatric low-grade glioma. The problem of finding a genetic target to improve treatment for this … Read more

Improving Everything: Movement and Exercise Helped Breast Cancer Patient Restore Her Mobility and More

 When Sandra Noack returned home from a visit to Bogota, Colombia, to visit her family, there was a letter waiting for her. It was a leaflet sent via the Massachusetts Department of Public Health describing a clinical trial at Dana-Farber Cancer Institute for Latina and Hispanic breast cancer survivors.  The trial didn’t involve any medicine. … Read more

Simone Ledward-Boseman Shares Advice with Dana-Farber Caregivers and Patients 

Simone Ledward-Boseman has many roles: She’s a writer, artist, and singer. And for some time, she was a caregiver to her late husband, Chadwick Boseman, the actor known for playing Black Panther and groundbreaking figures like James Brown and Jackie Robinson. These days, Ledward-Boseman has added more titles to her list: activist and advocate.  “I’m … Read more

Cervical Cancer Disparities: What to Know and Tips for Prevention 

Cervical cancer is caused by a virus called HPV (human papilloma virus) that is spread through sexual contact. For many people, the virus is cleared by the immune system. But if it isn’t, it can develop into cancer.   The virus can be detected through HPV screening that inspects a sample of cervical tissue for the … Read more

Boston Marathon Run is Mother-Daughter Moment for Breast and Uterine Cancer Survivor 

Runners call it Heartbreak Hill, but for Michelle O’Brien the long, rising stretch of pavement that crosses the 20-mile point of the Boston Marathon® route represents the top of the mountain.   Just over three years after being diagnosed in back-to-back months with two unrelated cancers — invasive breast cancer in December 2020, and then stage … Read more

What’s the Latest Research in Lynch Syndrome?  

Lynch syndrome is an inherited condition that increases an individual’s risk for certain types of cancer. It’s caused by a mutation in any of five specific genes: MLH1, MSH2, MSH6, PMS2, and EPCAM.   People born with a mutation in one or more of these genes have a significantly increased risk of developing colorectal or uterine cancer and a somewhat … Read more

Patient with Breast Cancer Lives Her Best Life with the Help of a Team 

Thirteen years after Vici Robinson was treated for estrogen receptor-positive breast cancer, she began experiencing shortness of breath. Her local physicians in New Hampshire determined her symptoms came from liquid that was filling her lung.  Then came the shocking news that this was caused by a breast cancer recurrence which had metastasized.  At 81, Robinson … Read more

Metastatic Breast Cancer Survivor Proves Her Endurance at NYC Marathon 

When Meghan MacDonald visited her primary care provider in the fall of 2022 to get a lump in her breast examined, they confirmed her suspicion that it was just an inflamed cyst. Relieved, MacDonald began a course of antibiotics, but when the lump didn’t go away, her doctor ordered a mammogram, and when the results … Read more

Young Mother with Lynch Syndrome Doing Well on Immunotherapy 

For a while, Stephanie Dobson attributed her gastrointestinal issues to her pregnancy. It was her second, a girl born in May 2023, a baby sister to her son. But when the symptoms persisted for the 34-year-old mother, she raised the issue with her primary care provider.   She was encouraged to see a gastroenterologist. On an … Read more

Bispecific Antibody Therapy for Lymphoma: What You Need to Know   

Bispecific antibody therapies are a type of immunotherapy for patients with B-cell non-Hodgkin lymphoma. These therapies provide a valuable new option for patients.  There are many standard therapies that are monoclonal antibodies. These therapies treat cancer by binding to a marker on cancer cells and rallying the immune system to destroy them.  Bispecific antibodies are … Read more

BCL2 Inhibitors: What’s the Latest Research?

BCL2 inhibitors are drugs that prompt cancer cells to die by altering the interactions among key proteins within the cells. They were clinically developed, in large part, by researchers at Dana-Farber and have been approved by the U.S. Food and Drug Administration (FDA) for the treatment of acute myeloid leukemia (AML) and chronic lymphocytic leukemia … Read more

A Patient-Doctor Bond Forged in Fighting Follicular Lymphoma  

Throughout the 20 years Robert Jenkins has been living with follicular lymphoma, he has been through many different treatments — from traditional chemotherapy protocols to innovative approaches like CAR T-cell therapy and bispecific antibodies. His lengthy survivorship has allowed Jenkins to benefit from new advances as they’ve emerged, and along with his wife, Lorna, one … Read more