What Causes Bone Cancer?

Cancers originating in the bone, called primary bone cancers, are rare and account for less than 1% of all cancers. There are numerous types of primary bone cancers, and in most cases, the cause isn’t known. Primary bone tumors can have changes in the DNA of the cancer cells, but those DNA changes are acquired … Read more

Researchers Set Sights on New Ovarian Cancer Treatment Strategies

Despite breakthrough treatments for high-grade serous ovarian cancer, about 80 percent of patients relapse within two years, often resistant to treatment. The good news is that Dana-Farber scientists are pursuing multiple avenues of research that very well may improve outcomes. “A number of patients develop progressive disease at a later point, potentially indicating that a … Read more

Patient-Derived Ovarian Cancer ‘Organoids’ Aid Precision Oncology Research

The time may not be far off when the treatment for a person’s ovarian cancer can be tailored to their malignancy using drugs selected by testing on “organoids” — miniature 3-D clusters of cancer cells grown from a patient’s own tumor cells. Although ovarian organoid tests are not yet being used to guide treatment decisions, … Read more

How Chromatin Remodelers Find Their Way to DNA

Studies in the lab of Cigall Kadoch, PhD, are shedding new light on how molecular machines called BAF chromatin remodeling complexes “go where they need to go” within the DNA genome of cells, binding to specific locations to govern which genes turn on and off to orchestrate cell functions. The findings, described in the journal … Read more

COVID-19 Booster Shots for Most Cancer Patients: What to Know

The U.S. Centers for Disease Control and Prevention (CDC) now recommend a third shot of the COVID-19 vaccine if you are being treated for cancer and have already received two doses of the Pfizer-BioNTech or Moderna COVID-19 vaccines.   Under the new CDC recommendation, people who are moderately to severely immunocompromised should get another dose. This means that most Dana-Farber patients who are currently being treated for cancer should get a third shot, … Read more

Dana-Farber Patient Benefits From ‘Growing Toolbox of Treatments’

When Dana-Farber launched its new Center for BRCA and Related Genes in August 2020, it was with patients like Janice Dolnick in mind. Dolnick’s cancer journey had already been a long one before she came to Dana-Farber for a consult in 2018. Over the previous 21 years, she’d been through two rounds of breast cancer … Read more

Tips for How Cancer Patients Can Quit Smoking

Quitting smoking during cancer treatment may seem overwhelming, but this is an especially important time to try. Active cancer patients and survivors who cut down on their cigarettes, vaping, or other nicotine use can experience a reduction in heart, stomach, and infection problems related to chemotherapy toxicity, improve their healing and breathing post-surgery, and decrease … Read more