Clinical Trial of New Targeted Agent a Boon for Patient With AML 

When Youling Sun was diagnosed in Shanghai, China, with acute myeloid leukemia (AML) in 2018, he called his son, Conghao, in Boston, for advice. His son’s message was unequivocal: Come to Boston for your treatment.  Today, Sun, a retired office worker from Shanghai, has multiple reasons to be thankful he took that advice — both … Read more

Multiple Myeloma Patient Shines Bright as CAR T-Cell Therapy Outpatient 

As a systems operator who works to help maintain the electrical grid for New York state, Brian Houlihan, 46, is used to getting power to the people. But when the multiple myeloma he has lived with since 2011 stopped responding to chemotherapy, it was Houlihan who needed a recharge.  He got it, through an innovative … Read more

What is Protein Degradation? 

Protein degradation is a natural process by which cells break down proteins that are damaged or no longer needed so they can be recycled or disposed of.  Scientists at Dana-Farber and elsewhere are harnessing this process to destroy specific proteins involved in cancer, an approach known as targeted protein degradation. In contrast to traditional targeted … Read more

Clinical Trials for Patients with Cancer 

Clinical trials are scientific studies in which new treatments — drugs, diagnostic procedures, and other therapies — are tested in people to find out if they are safe and effective. Nearly all cancer drugs in use today were tested in clinical trials.  If you have been diagnosed with cancer, the benefits of participating in a clinical … Read more