Dana-Farber Science Inspires Trial of Drug Combo for Ovarian Cancer 

As a post-doctoral fellow, Elizabeth Stover, MD, PhD, wanted to understand how ovarian cancer cells become resistant to chemotherapy. Chemotherapy becomes less effective over time for most patients with metastatic ovarian cancer.   She ran an unbiased screen – a way to look at every gene in the human genome and see which ones protect ovarian … Read more

FDA Approves Personalized Blood-Test Guided Immunotherapy for Bladder Cancer, Backed by Dana-Farber Science 

When patients with bladder cancer complete treatment that is intended to cure the cancer, they may be left wondering if there is anything else they should do to keep the cancer from coming back. For patients with muscle invasive bladder cancer – where the disease is at a higher risk of coming back than early-stage … Read more

Patient Finds Reassurance and Support After Rare Cancer Diagnosis

When Will Verbits noticed a cut on the side of his foot in the summer of 2024, he wasn’t worried. The longtime administrator of special education assumed he’d somehow gotten a blister. He was happily looking forward to retirement, eager to brush up on his cooking skills. But, over time, a lesion developed and grew. … Read more

Patient Finds Joy in Retirement After Enrolling in a Clinical Trial  

Pathogens are tiny invaders of the body that can make people sick—something that Howard Heller, MD, MPH, has spent his entire career studying. Then, in 2024, Heller discovered at age 64 there was another kind of invader, growing slowly and uncontrollably in his own body: cancer.   “I’ve helped patients as an infectious disease specialist for … Read more

Finding Empowerment Through a Lynch Syndrome Diagnosis 

In April, Riley McDevitt received test results from her genetic counselor at Dana-Farber. Tests showed a diagnosis of Lynch syndrome and McDevitt knew exactly what she wanted to do after hearing the news: celebrate with her family over tacos. The diagnosis wasn’t entirely unexpected. “I have a family history of Lynch syndrome, so I’ve known … Read more

Doctor by Day, Patient by Night: Young Sarcoma Survivor Overcomes Life Interrupted 

Bilasan Hammo, MD, had just turned 30, and everything seemed set up for a successful move into adulthood. As she wrapped up her residency at Cleveland Clinic Children’s, she landed a prestigious fellowship in Boston Children’s Hospital’s Gastrointestinal-Nutrition Department. Heavily influenced by her father – who is also a pediatric gastroenterologist – the fellowship felt … Read more

Rapid Epigenetic Test Could Speed Diagnostics for Acute Leukemias

Acute leukemias are life-threatening blood conditions that need urgent treatment. Approved targeted therapies such as BCL2, IDH, and menin inhibitors have expanded treatment options for certain patients, but determining if a given patient might benefit from one of these treatments can take time. Doctors need to order multiple complex diagnostic workups that can take days … Read more

Love, Advocacy, and Acceptance in the Face of Cancer

Before Mary and Abby Kissiday-Diamond were married, they met regularly at a Cambridge church for discussion groups hosted by the lesbian civil rights group, Daughters of Bilitis. Through 1969 to the early 2000s, these meetings were organized as a safe place for members of the lesbian community to express themselves. Mary was immediately intrigued by … Read more

New Options for Adolescent and Young Adult Patients with Sarcoma 

Sarcomas are cancers that occur in bone or soft tissue, such as muscles and fat. These cancers are rare and diverse, with more than 150 different variations.  Treatment is advancing for some sarcomas, but most forms of the disease are still treated using chemotherapy, radiation and/or surgery. In some cases, there are few options if the cancer comes back.  Dana-Farber physician-scientists are evaluating innovative new therapies in clinical trials … Read more