Combination Therapy Working Well for Patient with Cervical Cancer in Clinical Trial

Just as the COVID-19 pandemic was sending entire states into lockdown, Jill Bailey learned that her metastatic cervical cancer was beginning to break free of the grip of chemotherapy. It was March 2020. Scans showed that Bailey’s metastatic tumors, which had shrunk in response to chemotherapy and another drug, were slowly starting to grow. A … Read more

For Families of Children with Cancer, A New Focus on Hereditary Risk

Widespread testing of pediatric tumors has confirmed a long-held suspicion: far more of them have hereditary roots than was once thought. Physicians and researchers now estimate that at least 10% of cancers in children and adolescents, and probably many more, are linked to hereditary genetic mutations that increase cancer risk. The findings have changed the … Read more

Study Reveals Factor That Determines ‘Fate’ of Cancer Cells When Tumor Suppressor Gene Function is Restored

Many cancers develop from cells that have a malfunctioning tumor suppressor gene, p53, which normally helps control unchecked cell growth and prevent cancer. Some scientists are pursuing a strategy of restoring p53 gene function in cancer cells to stop their unruly growth or kill them. The exact effects of reviving p53 activity in tumors are … Read more

After Wilms Tumor Treatment, First Grade is First Rate for Pediatric Cancer Survivor

The last two school years will be remembered for the tremendous challenges they presented students due to COVID-19, but rising second-grader Caroline McMahan and her family were ready for the pandemic’s limitations after what they had already endured. By the time the pandemic began, Caroline, 7, was already adept at washing up, masking up, and … Read more

Patient with Cancer Shares Tips for Being Your Biggest Advocate

Life is like a Mad-Lib, and Jennifer White is taking control of what she can fill in the blank spaces. The Atlanta-based cyber security consultant was diagnosed with chronic lymphocytic leukemia (CLL) in January 2019. In July of that same year, White, a Boston native, came to Dana-Farber. She currently comes to Boston four times … Read more

What is a Cytokine Storm?

A cytokine storm is a severe immune system reaction to infection, autoimmune condition, or other disease, including some cancers. It occurs when the body produces extremely high levels of certain cytokines, which are proteins that raise or lower immune activity. The deluge of cytokines into the bloodstream can result in severe inflammation across multiple bodily … Read more

What is an Atypical Mole?

Atypical moles are irregular moles that can appear anywhere on the body. They are more commonly found on people with fair skin, as well as those with many freckles and moles on the body (more than 50). What do atypical moles look like? In order to spot atypical moles or something more serious, dermatologists recommend … Read more

What is Nasopharyngeal Cancer?

Nasopharyngeal cancer (NPC) is a type of throat cancer that forms in the nasopharynx, which is the upper part of the throat behind the nose. It is part of the passageway for the air from the nose to travel to the lungs. Nasopharyngeal cancer is rare, though it can occur at any age. In the … Read more

The Importance of LGBTQ+ Allies in the Healthcare Space

By Tara Baysol As my wife and I get ready to celebrate our 10-year wedding anniversary, I have been reflecting on the amazing journey we have had since tying the knot in 2011. While the decade has been filled with incredible love and exciting adventures, a significant part of our journey has also included navigating … Read more

New ‘Druggable’ Genetic Targets Identified in Rare Type of Bile Duct Cancer

Scientists are beginning to make inroads into treating cholangiocarcinoma, a rare, lethal cancer of the bile ducts, with precision drugs. Last year, the first targeted drug for some patients with the disease was approved. Now, Dana-Farber scientists say they have identified another genetic alteration in a small percentage of cholangiocarcinoma patients that can be attacked … Read more

Newborn Genetic Screening for Pediatric Cancer Risk Could Save Lives

Numerous genetic mutations increase children’s risk for various cancers. When they are detected early, cancers can potentially be caught at an early, more treatable stage — or avoided entirely. Could adding such “cancer predisposition” genes to routine newborn “heel-stick” screening save lives? Lisa Diller, MD, chief medical officer at the Dana-Farber/Boston Children’s Cancer and Blood … Read more