By Tom Ulrich One of the hot trends in drug discovery could be called drug re-discovery: finding new uses for drugs that have already received FDA approval for a different indication. It’s an approach that allows researchers and clinicians to rapidly test potential treatments for rare or difficult-to-treat conditions. Because the drug’s safety profile is already known, much of the preclinical and early clinical work that goes into developing a drug can be bypassed.
By Tom Ulrich Last month, the American Cancer Society (ACS) released “Cancer Statistics, 2014,” their annual estimate of new cancers diagnoses and deaths for the year ahead. The report was heavily focused on adult malignancies—not surprisingly, given that the number of adult cancer patients in the nation is orders of magnitudes greater than that of childhood patients—but did hold a few insights into childhood cancers.
Joanne Wolfe, MD, MPH, founded the Pediatric Advanced Care Team (PACT) in 1997 to help ensure children who are living with life-threatening diseases like cancer, and their families, enjoy the best quality of life. The program, a part of Dana-Farber/Boston Children’s Cancer and Blood Disorders Center and the Department of Psychosocial Oncology and Palliative Care, and Wolfe, were featured recently in The New Yorker. We spoke with her about the benefits of pain and symptom management, and palliative care for pediatric patients. Q. What is PACT? A. PACT is a group of physicians, social workers, and nurse practitioners. We provide …
As 2013 comes to a close, we’re looking back at some of our favorite Insight posts from the last year. From inspiring patient stories to important research, here is our top 10 list:
September is Childhood Cancer Awareness Month. We asked Lisa Diller, MD, chief medical officer at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, to answer these important questions. What signs might lead a child’s pediatrician to suspect cancer? Cancer is very diverse, and diagnosis is further complicated because many signs and symptoms—like fever, bruising and headaches—are normal in healthy children.
Jack Robinson is a special kid. Diagnosed with bone cancer at the age of 11, he tackled treatment if not with a smile on his face, then with a joke on his lips… or more accurately, on paper. The Massachusetts resident compiled and edited a joke book called, “Make ‘em Laugh” to help himself, and other kids who were sick. It was drafted from hundreds of jokes, riddles, and drawings submitted by Robinson and other kids cared for in the Jimmy Fund Clinic and the inpatient oncology floors at Boston Children’s Hospital.
By Saul Wisnia Rayquan “Ray” Fregeau’s smile lights up a room, even after five days of chemotherapy. His upbeat personality infuses his poetry, but until recently the 17-year-old patient at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center had trouble putting into words what he’s gone through since his February cancer diagnosis, especially when it came to telling friends about his experience.