Glioblastoma Patient Enjoys Steady Health and New Adventures

If you happened to be looking for Alex Epshteyn this past winter, you might have found him on the ski slopes. The Charlestown, Massachusetts resident took up the sport just two years ago and has since been enthusiastically sharpening his skills. “I’m overcoming my fear and making progress, which is a great feeling,” Epshteyn says. … Read more

Drugs Targeting a Pathway in Glioblastoma Must Clear a High Bar, Study Suggests

Researchers had every reason to expect that a compound called BKM120 (also known as buparlisib) would stifle glioblastoma brain tumors lacking the protein PTEN. After all, it was known to block the tumor-promoting PI3K protein and could easily pass through the blood-brain barrier — the dense layer of cells that guards entry to the brain … Read more

Avastin Helps Patients with Glioblastomas, Doctors Say

The drug Avastin, when added to initial therapy for glioblastoma, can give patients a few extra months’ reprieve before their brain tumors start growing again, but does it make their quality of life better – or worse?

That’s a matter of heated debate for doctors – and confusion for patients – after two large clinical trials reported conflicting results at the annual American Society of Clinical Oncology (ASCO) conference in June. Some experts contend that Avastin lacked sufficient benefit for use as an “upfront” treatment for glioblastomas – the most common and aggressive brain tumors.

Read more