Medically reviewed by Nancy U. Lin, MD When cells from a breast tumor metastasize — spread through the circulation to other tissues and organs — they can migrate to the brain and form secondary tumors, termed metastases (or “mets”) there. This is especially true of the more aggressive breast cancer types. “As many as half … Read more
In most cases, the diagnosis of a brain tumor can’t be traced to a particular cause or risk factor. As with many forms of cancer, brain tumor risk increases with age – although tumors can develop in younger people – and men have a somewhat greater risk than women. About five percent of brain tumors … Read more
It’s 19 months after being diagnosed with the aggressive brain tumor, glioblastoma, and Andrew Wall is itching to go back to work as a police officer. “Sitting around is not my thing,” says Wall, 53, who hasn’t yet been cleared to return to work as a police officer in Monroe, Connecticut – a job he has … Read more
In honor of Brain Tumor Awareness Month, David Reardon, MD, and Patrick Wen, MD, of Dana-Farber’s Center for Neuro-Oncology, went live on Facebook to answer questions about brain cancer. The doctors discussed advice for brain tumor patients, answered audience questions, and described the difference between the two major categories of brain cancers—primary cancer, developed in … Read more
The brain controls many vital bodily functions – and when a tumor grows into or presses on an area of the brain, it may stop that part of the brain from functioning normally. Nearly 80,000 new cases of primary brain tumors are expected to be diagnosed this year, according to the American Brain Tumor Association. … Read more
For many brain tumor patients, surgery is an important step in the treatment process. While recovering from brain surgery can be a difficult process, your care team will help support you through treatment and guide you through the recovery process. Once a patient is cleared by their care team for walking after brain surgery, light … Read more
By Tara Baysol My first truly extensive exposure to the health care system as a patient began in 2013 with my brain cancer diagnosis. It was, and continues to be, an eye-opening experience. One big challenge that presented itself early on in my cancer journey was learning how to navigate the system and advocate for … Read more
With football season in full swing, concussions and their long- and short-term consequences promise to be in the news. While the harmful effects of repeated concussions, especially among teens and young adults, have been well documented, any links between concussions and brain cancer are less clear. Multiple studies have endeavored to see if such links … Read more
Brain tumors can be among the most challenging cancers to treat. The blood-brain barrier, a natural defense mechanism that shields the brain from harm, can also prevent cancer treatments from reaching tumors. “It can be difficult to get treatments effectively into the brain,” says David Reardon, MD, clinical director of Dana-Farber’s Center for Neuro-Oncology. However, … Read more
The blood-brain barrier surrounds the brain and prevents harmful toxins and bacteria in the blood stream from entering the vital organ. What evolved as a life-saving defense, however, also blocks many drugs from reaching the brain, creating a major problem in treating brain tumors. The blood-brain barrier is formed by tightly-packed cells lining the walls … Read more
Historically, brain tumors have been some of the most challenging types of cancers. A protective barrier around the brain—called the “blood-brain barrier”—can prevent cancer treatments from reaching the tumor. Recently, increased interest in immunotherapy has given new hope to getting through this barrier. “We know the immune system can get into the brain to fight … Read more
Brain tumors are relatively rare for people of any age, but they can occur in both children and adults. In fact, tumors of the spinal cord and brain are the second most common types of cancer in children, after leukemia. But there are some key differences between brain tumors that occur in adults and those … Read more
Brain cancer takes a variety of forms – and research to better understand and treat it is progressing on a variety of fronts. One area of focus is the tumor microenvironment the skein of tissues and blood vessels that feed and support a tumor. Researchers are exploring how newly formed brain tumors interact with surrounding … Read more
This post originally appeared on HealthHub, a blog from Brigham and Women’s Hospital. Interested in seeing images of his brain, Steven Keating, currently a graduate student at the MIT Media Lab, volunteered for a research study while attending school in Canada in 2007. When researchers returned his brain scans, they delivered some startling news. “The … Read more
Until a few years ago, there were only a handful of known survivors of atypical teratoid rhabdoid tumor (AT/RT), a rare cancer that affects the brain and central nervous system. When researchers at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center studied how these few survivors were treated, they found three had been given an unusual … Read more
The information used in diagnosing a brain tumor takes many forms. At Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC), patients’ brain tumor tissue undergoes a broad range of diagnostic tests: not only standard pathology exams in which tumor cells are viewed under a microscope, but also next-generation scans for mutated genes and misassembled chromosomes, as well … Read more
Researchers in Dana-Farber’s Center for Neuro-Oncology are now launching attacks on glioblastomas from a new angle – by turning the patient’s immune system against the cancer cells. Where targeted chemotherapy uses drugs to disable proteins that cancer cells need to grow, immunotherapy drugs stimulate the patient’s immune system to recognize and kill cancer cells. Traditional drugs … Read more
On December 5, just after the students of Carolyn Bever’s Violin Studio finish playing “The First Noel” for the residents of the Pines Senior Living Community in South Burlington, Vermont, 9-year-old Sophie Fellows quietly leaves the stage because of a headache. The next day she is diagnosed with a brain tumor, and the following day … Read more
For many patients with brain tumors or other abnormal tissue located deep in the brain, treatment options have been limited. Last year, Jill Colter, now 50, discovered that a brain tumor resulting from Stage IV melanoma had returned. “Several years earlier, I had treatment with surgery and radiation, but the tumor came back,” Jill said. … Read more
Glioblastomas are the most common primary cancer of the brain, with 13,000 new cases being diagnosed each year in the United States. Although it is a fast-moving cancer, doctors know a lot about this type of tumor and are finding ways to fight it. Here are five things you need to know about glioblastomas. 1. … Read more