Helping Cancer Survivors Get a Good Night’s Sleep

Sarah Boczanowski was tired. Her turbulent relationship with sleep, dating back to her childhood, had only worsened since her leukemia diagnosis at age 18. Through biopsies and chemotherapy, she found sleep elusive. “With nurses and doctors coming in and out, and beeping noises from my IVs, it was impossible to sleep,” she says. Boczanowski is … Read more

New Immunotherapy Vaccines Show Promise in Treating Brain Tumors

Researchers in Dana-Farber’s Center for Neuro-Oncology are now launching attacks on glioblastomas from a new angle – by turning the patient’s immune system against the cancer cells. Where targeted chemotherapy uses drugs to disable proteins that cancer cells need to grow, immunotherapy drugs stimulate the patient’s immune system to recognize and kill cancer cells. Traditional drugs … Read more

20 Years After BRCA: What We’ve Learned About Genetics and Breast Cancer

Twenty years ago, scientists announced the discovery of BRCA1, which arguably has become the best-known cancer susceptibility gene in the world. When inherited in a mutated form, the gene sharply increases a woman’s chances of developing breast or ovarian cancer, often at an early age. The discovery has changed the way women with a family … Read more

Lymphoma Survivor Tackles Breast Cancer While Helping Fellow Patients

When you’re 21, the last words you expect to hear are “you have cancer.” But, that was exactly the news I received in 1976 after a routine trip to my college infirmary landed me in Boston Children’s Hospital with Hodgkin lymphoma. Thanks to new treatments developed through clinical trials and a summer undergoing radiation therapy … Read more

Five Things You Need to Know About Cancer Genetics

Although most cancers are sporadic or occur by chance, a small percentage are due to inherited genetic (or germline) mutations, which can often be identified through genetic testing. These mutations are different from somatic mutations, which are not inherited, but occur during one’s lifetime. Profile, a research project launched by Dana-Farber and Brigham and Women’s Hospital, … Read more

CELLmates Take on Boston Marathon

By Tim O’Neill In 2006, my then 33-years-young wife, Kirsten, was diagnosed with Stage III rectal cancer. Her diagnosis was completely unexpected; she was young, a non-smoker and in overall good health. She had chemotherapy and multiple surgeries. Thankfully, we navigated the treatment with an excellent team of healthcare providers, loving family and caring friends. … Read more

Cancer Immunology at Dana-Farber

Immunotherapy – stimulating the body’s defenses to recognize and destroy disease-causing cells and proteins – was dubbed the “breakthrough of the year” in 2013 by Science magazine. Dana-Farber researchers have contributed many important discoveries over the years about how the immune system works. Now, they are building on these insights to develop immunotherapy against tumors … Read more

Hodgkin Lymphoma: Five Things You Need to Know

Approximately 173,000 people in the United States are living with Hodgkin lymphoma, or are in remission. Less common than non-Hodgkin lymphoma, Hodgkin lymphoma (sometimes referred to as Hodgkin’s lymphoma) is a malignancy of B lymphocytes, an important cell in the immune system. This malignant B cell is known as the Reed-Sternberg cell. Arnold Freedman, MD, … Read more

What’s the Difference Between Donating Bone Marrow and Donating Stem Cells?

Stem cell transplantation (sometimes called bone marrow transplants) is a treatment for certain forms of cancer, such as leukemia, lymphoma, and multiple myeloma, as well as other diseases. But before a patient can receive a transplant, stem cells must be collected from a donor (an allogeneic donation) or from the patient (an autologous transplant).

Clinical Trials and the Future of Lymphoma Treatment

Current lymphoma therapies are a far cry from the mustard gas used more than 50 years ago. More treatment options, including ones that may be more effective and less toxic, are being studied in ongoing clinical trials. “Clinical trials really are the future of lymphoma treatment,” says Ann LaCasce, MD, a medical oncologist in the … Read more