Genetic counseling now recommended for children with sarcoma

If your son or daughter has been diagnosed with a type of sarcoma – a tumor in connective tissue like muscles or bones – there are many questions: Will my child make a full recovery? What are the immediate and long-term side effects of treatment? Most parents don’t consider whether their child will face a second cancer later in life. However, a link between sarcomas and Li-Fraumeni syndrome, a rare condition that raises a person’s risk of developing one or more cancers to as high as 85 percent, has led genetic specialists at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center …

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The most talked about cancer stories of 2011

The face of cancer care in 2011 changed in encouraging and – in some cases – challenging ways. Here are some of the cancer stories that captured the most press attention in 2011.  A federal task force recommended against routine testing of healthy men for the prostate-specific antigen (PSA), which can be a sign of prostate cancer. However, Dana-Farber’s Philip Kantoff, MD, called the message “misguided” and said that oncologists are using the test to find those who may benefit from screening and treatment.

Obesity and cancer: What’s the link?

There are a lot of good reasons not to gain too much weight, but you might not be aware of this one: Growing evidence links obesity to a higher risk of developing cancer, and being overweight may worsen a cancer patient’s outlook. Although more and more studies are finding this connection, scientists haven’t uncovered the biological mechanisms by which excess pounds make normal cells more likely to turn cancerous. But they are pursuing a large number of leads, some of which may uncover new ways of fighting cancer – including losing weight.

Do viruses cause cancer?

In 1958, when scientists linked an aggressive form of leukemia to infection with a particular virus, some researchers took the discovery as evidence that nearly all cancers are caused by viruses. A cover story in Life magazine in 1962 proclaimed, “Cancer may be infectious.” Today, it is estimated that viruses are responsible for almost 20 percent of cancer cases worldwide. Seven viruses have been connected to specific types of malignancies; it’s now known, for example, that the human papillomavirus (HPV) causes cervical cancer and some types of head and neck cancer. While viruses can cause cancer in a variety of …

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The benefits of vitamin D

Activated by sunlight and present in some foods and supplements, vitamin D has been associated with healthy bones and reducing the risk of diabetes and cancer. But a new study says that the recommended dose of vitamin D needed to reap these health benefits remains unclear. To help shed some light on the topic, we talked to Dana-Farber’s Kimmie Ng, MD, MPH, who has been studying the connection between cancer and vitamin D use, as well as other lifestyle factors. What is the connection between cancer and vitamin D? There is a large amount of scientific and observational data that …

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The War on Cancer, 40 years later

Friday, December 23, marks the 40th anniversary of President Richard Nixon’s declaration of a national “War on Cancer.” On that date in 1971, Nixon signed the National Cancer Act, which allocated $1.5 billion over three years for cancer research and control. He declared, “I hope that in the years ahead we may look back on this day and this action as being the most significant action taken during this Administration.” Forty years later, the War on Cancer can claim countless successes against one of the most resilient and recalcitrant enemies mankind has faced. Some cancers that were once almost invariably …

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Blood cancer research may lead to new treatments

At this year’s American Society of Hematology Annual Meeting, Dana-Farber scientists presented major findings that could one day improve diagnosis and treatment of blood cancers, extend life, or even cure some diseases. Among the highlights: Steven Treon, MD, PhD, and his colleagues identified a gene mutation that underlies the vast majority of cases of Waldenström’s macroglobulinemia, a rare form of non-Hodgkin lymphoma. The results suggest that new, effective treatments are now possible for people with Waldenström’s. Read more about Dr. Treon’s Waldenström’s macroglobulinemia research breakthrough. Catherine J. Wu, MD, co-led investigators who discovered nine new gene mutations that could help …

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Breast cancer specialist discusses treatment advances

Harold J. Burstein, MD, PhD, a Dana-Farber breast cancer specialist, discusses some of the important studies presented at the 2011 CTRC-AACR San Antonio Breast Cancer Symposium. The five-day meeting includes more than 1,000 scientific presentations, seminars, and posters, with a focus on emerging treatments in hard-to-treat populations, patients with metastatic breast cancer, and breast cancer prevention and risk. Around 8,000 breast cancer experts from 90 countries are attending the symposium to learn about the latest developments in breast cancer care and research.