What are Cancer Vaccines?

Cancer vaccines are a form of immunotherapy aimed at enhancing the immune system’s ability to recognize and attack cancer cells, or to protect against certain forms of cancer caused by viruses. Vaccine can help prevent some cancers There are two approved preventive vaccines directed against cancer-causing viruses.  Vaccines against cancer-causing or other infectious microbes typically … Read more

Gynecological Cancer Patients Find Safety, Solidarity in Support Group

Deb Petrishen says well-meaning but frustrating interactions can occur everywhere, from the grocery store to family functions. Although friends and loved ones are often sensitive and supportive, some may not know what to say to someone with stage III ovarian cancer, especially after two recurrences. Petrishen has just as much difficulty explaining her feelings. Except … Read more

What You Should Know About Cervical Cancer [Webchat]

Unlike many gynecologic cancers, there is a vaccination and screening test for cervical cancer, an important distinction in preventing and identifying the disease, according to Ursula Matulonis, MD, medical director of Gynecologic Oncology in Dana-Farber’s Susan F. Smith Center for Women’s Cancers, and Colleen Feltmate, MD, director of minimally invasive surgery in Gynecologic Oncology at … Read more

If I’ve Had a Gynecologic Cancer, Can I Have Children?

Fertility is a common concern among newly diagnosed cancer patients. For women with gynecologic cancer, the ability to have children depends on the type of cancer a woman has and the stage at which it is diagnosed, says Colleen Feltmate, MD, director of Minimally Invasive Surgery in Gynecologic Oncology at Dana-Farber/Brigham and Women’s Cancer Center. … Read more

Cancer Conversations Podcast – Episode #6: Cervical Cancer Research, Treatment and Prevention

Although cervical cancer incidence and death rates have decreased thanks to regular screenings, thousands of women in the U.S. are still affected by the disease every year. In this Cancer Conversations podcast episode, Ursula Matulonis, MD, medical director of the Gynecologic Oncology Program in the Susan F. Smith Center for Women’s Cancers at Dana-Farber, joins … Read more

What Are the Symptoms of Cervical Cancer?

Cervical cancer screenings, which typically include a pelvic exam and Pap smear, have significantly reduced the number of cervical cancer incidence and death rates in the United States. These screenings are especially important because symptoms of cervical cancer often go undetected until the disease is more advanced. “The vast majority of cervical cancers are early … Read more

How Is Surgery Used to Treat Gynecologic Cancers?

Many associate cancer treatment with chemotherapy and radiation therapy, but for many women with gynecologic cancers, surgery is often the first line of defense. Colleen Feltmate, MD, director of minimally invasive surgery in gynecologic oncology at Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC), shares insight into surgical options to treat these cancers. Minimally Invasive vs. Open … Read more

The Latest in Cervical Cancer Treatment, Research and Prevention

Although cervical cancer is relatively rare in the United States, approximately 11,000-12,000 women in the U.S. are diagnosed with the disease each year. Globally, that number grows to more than 500,000 diagnoses each year, making it the fourth most common women’s cancer worldwide. As January marks Cervical Cancer Awareness Month, the Susan F. Smith Center … Read more

DNA Test May Offer Alternative to Pap Smear

A Food and Drug Administration (FDA) panel has recommended that a DNA test should be the primary screening tool for cervical cancer, rather than the traditional Pap smear. The DNA test detects the DNA of human papillomavirus (HPV), the sexually transmitted infection that causes almost all cases of cervical cancer.

“This is an important step forward for cervical cancer screening,” says Alexi Wright, MD, MPH, a medical oncologist in the Susan F. Smith Center for Women’s Cancers at Dana-Farber. Specifically, the DNA test screens for HPV-16 and HPV-18, the two highest-risk HPV strains, as well as 12 other high-risk HPV types, using a blood sample.

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When Should My Daughter Get Her First Pap Test?

By Sarah Feldman, MD, MPH

Pap testHealthy young women should get their first Pap test at age 21. If that test is normal, they should have additional Pap tests every three years. If they have symptoms such as abnormal bleeding or are found to have an abnormality on their cervix during an exam, they may need a diagnostic Pap for cervical cancer earlier. Immunosuppressed women should start Pap testing with the onset of sexual activity, then repeat annually.

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