A group of specialists at the National Cancer Institute recently issued a report calling for a redefinition of the word “cancer,” suggesting that it no longer be applied to certain premalignant and non-lethal conditions. Such a change, the panel wrote, may ease the fears of patients, making them less inclined to seek unnecessary and potentially harmful treatments. The findings reinforce earlier studies by physicians at Dana-Farbers’ Susan F. Smith Centers for Women’s Cancers and others. An example of this kind of condition is ductal carcinoma in situ (DCIS), in which cancerous cells are confined to the milk ducts of the breast. …
by Richard Saltus Living with cancer is a physical and emotional challenge, but people may also find it hampers their thought processes and memory. Often the deficits are temporary, but sometimes they persist or appear months or years later as delayed effects. Cognitive difficulties, says Clare Humphreys, PhD, a neuropsychologist at Brigham and Women’s Hospital, “are caused not just by the direct effect of cancer, but also the effects of treatment, as well as factors like pain, disrupted sleep, anxiety, and depression.”
There are many decisions parents face after testing for genetic cancer risk, including whether to tell their children and how to approach the conversation. If you decide to talk to your children about the test results, allow yourself some time to process the information; you want to be calm and clear when you talk with them. Remember that you know your children best and there are no set rules for talking to kids about genetic tests.
Liz Moroney celebrated her 23rd birthday in an unusual place — at a fertility clinic. Liz, a recent college graduate, wanted to plan for having children before it was too late. Diagnosed with Hodgkin’s lymphoma in June 2010, she spent 4 months in chemotherapy treatment in New York. Afterward, she and her reproductive endocrinologist watched her fertility numbers dwindle over a year of visits. Her endocrinologist was skeptical of the effectiveness of fertility treatment; So, too, was Liz.
The drug Avastin, when added to initial therapy for glioblastoma, can give patients a few extra months’ reprieve before their brain tumors start growing again, but does it make their quality of life better – or worse? That’s a matter of heated debate for doctors – and confusion for patients – after two large clinical trials reported conflicting results at the annual American Society of Clinical Oncology (ASCO) conference in June. Some experts contend that Avastin lacked sufficient benefit for use as an “upfront” treatment for glioblastomas – the most common and aggressive brain tumors.
By Leonard Ansin In January 2012, my wife and I had left Boston to spend a few months in sunny Florida. We had just passed Orlando when my cell phone rang. It was my primary care physician calling to tell me she was concerned that my PSA was elevated to 6, which showed that I did have a problem with my prostate. This is where it all started.
When solid tumors are diagnosed, they are often assigned a grade and a stage. The grade of a tumor is an indication of how quickly it is likely to grow and spread. In general, low-grade tumors grow slowly and higher-grade tumors grow more rapidly. Tumors are assigned a grade based on the appearance of their cells under a microscope: Low-grade tumor cells resemble normal cells more closely than high-grade tumor cells do.
By Robert Haddad, MD Human papillomavirus, or HPV, vaccinations were originally advised only for girls. The Centers for Disease Control and Prevention (CDC) and the American College of Pediatrics now recommend that both girls and boys be vaccinated. The recommendations are well founded: HPV infection is the number one cause of oropharyngeal cancer, which occurs in the middle part of the throat and is diagnosed in about 14,000 Americans each year. Men are three times more likely than women to develop oropharyngeal cancers linked to HPV.
By Lyndsay McCaffery The first year of your baby’s life is special. They come home to you this eating, pooping, screaming machine and twelve months later they are their own walking and babbling little person. It is a year to truly cherish because you realize what parents mean when they say, “they grow up so fast.” Well, my baby’s year is going by incredibly fast. He is a crawling, smiling, happy boy. Meanwhile, I feel I have hardly moved at all. A shocking diagnosis interfered with what was supposed to be the happiest time in my life. What do you …
By Saul Wisnia Wendy Akeson is passionate about both running and donating platelets. Never has she felt such a strong connection between these two roles as she did this year. Four minutes after completing her 10th consecutive Boston Marathon, Akeson heard the explosions that will forever link this year’s marathon with tragedy – and then saw people running toward her from the finish line she had just crossed.